Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   PYW32_RS00270 Genome accession   NZ_CP118957
Coordinates   54364..55608 (+) Length   414 a.a.
NCBI ID   WP_016176087.1    Uniprot ID   -
Organism   Enterococcus saccharolyticus subsp. saccharolyticus strain DSM 20726     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 49364..60608
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PYW32_RS00245 mscL 49455..49919 (-) 465 WP_245558560.1 large conductance mechanosensitive channel protein MscL -
  PYW32_RS00250 yfmF 50076..51335 (+) 1260 WP_016176083.1 EF-P 5-aminopentanol modification-associated protein YfmF -
  PYW32_RS00255 yfmH 51337..52632 (+) 1296 WP_016176084.1 EF-P 5-aminopentanol modification-associated protein YfmH -
  PYW32_RS00260 - 52705..53616 (+) 912 WP_016176085.1 helix-turn-helix domain-containing protein -
  PYW32_RS00265 pgsA 53657..54238 (+) 582 WP_016176086.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  PYW32_RS00270 cinA 54364..55608 (+) 1245 WP_016176087.1 competence/damage-inducible protein A Machinery gene
  PYW32_RS00275 recA 55719..56759 (+) 1041 WP_016176088.1 recombinase RecA Machinery gene
  PYW32_RS00280 rny 57025..58581 (+) 1557 WP_016176089.1 ribonuclease Y -
  PYW32_RS00285 - 58648..58863 (+) 216 WP_016176090.1 hypothetical protein -
  PYW32_RS00290 - 58933..59127 (+) 195 WP_016176091.1 hypothetical protein -
  PYW32_RS00295 - 59124..59369 (+) 246 WP_016176092.1 hypothetical protein -

Sequence

Protein


Download         Length: 414 a.a.        Molecular weight: 45447.51 Da        Isoelectric Point: 4.5299

>NTDB_id=796776 PYW32_RS00270 WP_016176087.1 54364..55608(+) (cinA) [Enterococcus saccharolyticus subsp. saccharolyticus strain DSM 20726]
MKAEIIAVGTELLLGQVVNTNATFLSEELAGLGIDVYYHSVVGDNAERLESLLELADQRSELIVLCGGLGPTEDDLTKQV
TAAHVGQELVRDEVGYQNLLSFFEKRQRPMTENNLLQTLVFKEGISLQNSAGLAVGIFYTSIKGNHYLLLPGPPSELKPM
FYHEVVPLLQKQFQKEEQLISRVLRFYGIGESQLVTDLADLIQGQTNPTIAPYAKPNEVTLRLTVKTTDETEAITQLDVL
EAVIQERVGEFFYGYGEENSLANVVVDLLKEKQQTLTAAESLTAGAFQSALGDISGVSEVFLGGFVTYSAQTKANFLGID
RDFLEQVGTVSQACVEQMALHARKLAQTDYSVAFSGVAGPNELEGQPAGTVWIALASEQGVHSQKYHFSRDRSYIRHSAV
MAGLDLLRRELLNK

Nucleotide


Download         Length: 1245 bp        

>NTDB_id=796776 PYW32_RS00270 WP_016176087.1 54364..55608(+) (cinA) [Enterococcus saccharolyticus subsp. saccharolyticus strain DSM 20726]
ATGAAGGCAGAAATTATTGCAGTAGGAACCGAGTTGTTATTGGGGCAAGTAGTCAATACAAATGCGACTTTTTTATCAGA
AGAATTAGCAGGATTAGGCATTGATGTTTATTATCATAGCGTGGTAGGTGATAATGCAGAACGTTTGGAATCATTGCTAG
AGTTAGCAGATCAACGTAGTGAATTGATTGTTTTGTGTGGGGGCTTAGGACCCACCGAAGACGATTTAACCAAACAAGTC
ACAGCAGCGCATGTAGGGCAAGAATTAGTGCGCGATGAAGTAGGGTATCAAAATTTACTATCATTTTTTGAAAAACGCCA
ACGCCCTATGACGGAAAATAATCTTTTGCAAACGTTAGTTTTTAAAGAAGGTATTTCATTGCAAAATAGCGCTGGTTTAG
CGGTAGGTATCTTTTATACTTCTATTAAGGGAAATCATTACTTACTACTTCCAGGCCCCCCTAGCGAGCTAAAACCGATG
TTCTATCACGAAGTCGTACCTTTGCTTCAAAAACAATTCCAAAAAGAAGAACAATTAATTTCTCGTGTGTTACGTTTTTA
TGGGATTGGTGAATCACAATTAGTTACGGACTTAGCAGATTTGATTCAAGGCCAAACGAATCCTACGATTGCGCCTTATG
CAAAACCAAATGAAGTAACGTTGCGTTTAACGGTCAAAACAACCGATGAAACCGAAGCAATCACTCAACTGGATGTATTA
GAAGCAGTCATTCAAGAACGAGTCGGCGAATTTTTCTATGGTTATGGCGAGGAAAATTCATTGGCCAATGTCGTGGTTGA
TTTATTAAAAGAAAAACAGCAAACTTTAACAGCCGCAGAAAGTCTCACAGCAGGCGCTTTTCAGTCAGCATTAGGAGATA
TTTCTGGTGTTTCTGAAGTGTTTTTGGGTGGATTTGTCACATATTCTGCACAAACAAAAGCGAATTTTCTAGGAATTGAT
CGCGACTTTTTAGAACAAGTTGGCACAGTGAGTCAAGCATGTGTTGAACAAATGGCTCTGCATGCACGCAAATTGGCACA
GACAGATTATTCAGTAGCTTTTAGTGGGGTAGCTGGACCAAATGAATTAGAAGGGCAACCAGCGGGAACTGTGTGGATTG
CTTTAGCAAGTGAGCAAGGTGTCCATAGTCAAAAATACCATTTTAGTAGAGATCGCAGTTACATTCGTCATAGTGCAGTA
ATGGCAGGACTTGATTTGCTTCGTCGAGAACTTTTAAATAAATAG

Domains

Predicted by InterproScan.

Damage-inducible protein CinA KH domain (CinA_KH)

(181-254)

Competence-damaged protein (CinA)

(259-411)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-170)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mutans UA159

53.717

100

0.541
  cinA Streptococcus mitis NCTC 12261

52.123

100

0.534
  cinA Streptococcus mitis SK321

51.887

100

0.531
  cinA Streptococcus pneumoniae TIGR4

51.185

100

0.522
  cinA Streptococcus pneumoniae D39

50.948

100

0.519
  cinA Streptococcus pneumoniae Rx1

50.948

100

0.519
  cinA Streptococcus pneumoniae R6

50.948

100

0.519
  cinA Bacillus subtilis subsp. subtilis str. 168

46.731

99.758

0.466
  cinA Streptococcus suis isolate S10

45.06

100

0.452