Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA/celA/cilE   Type   Machinery gene
Locus tag   PW252_RS08195 Genome accession   NZ_CP118735
Coordinates   1686887..1687546 (-) Length   219 a.a.
NCBI ID   WP_248050982.1    Uniprot ID   A0AA96VLK6
Organism   Streptococcus iners strain 29887     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1681887..1692546
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PW252_RS08190 (PW252_08195) comEC/celB 1684666..1686903 (-) 2238 WP_248050981.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  PW252_RS08195 (PW252_08200) comEA/celA/cilE 1686887..1687546 (-) 660 WP_248050982.1 helix-hairpin-helix domain-containing protein Machinery gene
  PW252_RS08200 (PW252_08205) - 1687690..1688523 (-) 834 WP_248050983.1 ABC transporter permease -
  PW252_RS08205 (PW252_08210) - 1688532..1689467 (-) 936 WP_105118382.1 ABC transporter permease -
  PW252_RS08210 (PW252_08215) - 1689863..1690798 (-) 936 WP_248043681.1 DUF2817 domain-containing protein -
  PW252_RS08215 (PW252_08220) - 1690801..1691544 (-) 744 WP_248050984.1 ABC transporter ATP-binding protein -
  PW252_RS08220 (PW252_08225) - 1691560..1692327 (-) 768 WP_248050985.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 23225.77 Da        Isoelectric Point: 4.0766

>NTDB_id=794746 PW252_RS08195 WP_248050982.1 1686887..1687546(-) (comEA/celA/cilE) [Streptococcus iners strain 29887]
MDTIKTYIEMLKEYKWQIALPAAAGLLLTTFLMFSQPAKSDQTGLTDFPQTEQTSSSSELVEENSTEESEESSQLVVDVK
GAVEKPGLYTLEAGARVNDAVDAAGGLTSQADPKSINLAQKLSDEAVVYVASKDEKISVVASTTASSAMSPEGNESKVNL
NTATEADLQTISGIGAKRAADIIAYREANGGFKSVDDLNNVSGIGDKTMESIRPYVTVD

Nucleotide


Download         Length: 660 bp        

>NTDB_id=794746 PW252_RS08195 WP_248050982.1 1686887..1687546(-) (comEA/celA/cilE) [Streptococcus iners strain 29887]
ATGGATACAATCAAAACTTATATAGAAATGCTTAAAGAATACAAGTGGCAGATTGCTCTGCCAGCAGCTGCAGGTTTGCT
TCTGACGACATTCTTAATGTTCAGTCAACCTGCCAAGTCTGATCAGACAGGACTGACAGACTTTCCACAGACCGAGCAAA
CTTCTAGCAGCTCTGAGTTGGTCGAGGAAAACAGTACAGAAGAAAGTGAGGAGTCCAGCCAGCTGGTCGTTGATGTCAAG
GGAGCGGTGGAAAAGCCGGGGCTCTACACTTTAGAAGCTGGTGCGCGTGTTAATGATGCGGTTGATGCGGCTGGCGGTTT
GACCAGTCAGGCAGACCCCAAGTCTATCAATCTGGCTCAGAAGCTCAGCGACGAGGCGGTGGTCTATGTGGCCAGCAAGG
ACGAAAAGATCTCGGTGGTAGCCAGCACGACTGCCAGCTCTGCTATGTCCCCAGAAGGAAATGAAAGTAAGGTCAATCTC
AACACGGCGACCGAGGCGGATCTGCAGACCATTTCCGGTATCGGTGCCAAGCGGGCGGCGGACATTATCGCCTATCGTGA
GGCCAATGGTGGCTTCAAGTCGGTGGACGACCTCAACAATGTGTCGGGTATCGGCGACAAGACCATGGAAAGCATCAGGC
CTTATGTCACGGTCGATTAA

Domains

Predicted by InterproScan.

SLBB domain (SLBB)

(76-130)

Helix-hairpin-helix motif (HHH_3)

(154-217)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

49.77

99.087

0.493
  comEA/celA/cilE Streptococcus pneumoniae Rx1

49.309

99.087

0.489
  comEA/celA/cilE Streptococcus pneumoniae D39

49.309

99.087

0.489
  comEA/celA/cilE Streptococcus pneumoniae R6

49.309

99.087

0.489
  comEA/celA/cilE Streptococcus mitis SK321

47.964

100

0.484
  comEA/celA/cilE Streptococcus mitis NCTC 12261

47.926

99.087

0.475
  comEA Streptococcus thermophilus LMD-9

59.748

72.603

0.434
  comEA Lactococcus lactis subsp. cremoris KW2

38.71

99.087

0.384
  comEA Bacillus subtilis subsp. subtilis str. 168

39.713

95.434

0.379