Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEC/celB   Type   Machinery gene
Locus tag   PW252_RS08190 Genome accession   NZ_CP118735
Coordinates   1684666..1686903 (-) Length   745 a.a.
NCBI ID   WP_248050981.1    Uniprot ID   A0AA96VM47
Organism   Streptococcus iners strain 29887     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1679666..1691903
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PW252_RS08190 (PW252_08195) comEC/celB 1684666..1686903 (-) 2238 WP_248050981.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  PW252_RS08195 (PW252_08200) comEA/celA/cilE 1686887..1687546 (-) 660 WP_248050982.1 helix-hairpin-helix domain-containing protein Machinery gene
  PW252_RS08200 (PW252_08205) - 1687690..1688523 (-) 834 WP_248050983.1 ABC transporter permease -
  PW252_RS08205 (PW252_08210) - 1688532..1689467 (-) 936 WP_105118382.1 ABC transporter permease -
  PW252_RS08210 (PW252_08215) - 1689863..1690798 (-) 936 WP_248043681.1 DUF2817 domain-containing protein -
  PW252_RS08215 (PW252_08220) - 1690801..1691544 (-) 744 WP_248050984.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 745 a.a.        Molecular weight: 84032.99 Da        Isoelectric Point: 7.5957

>NTDB_id=794745 PW252_RS08190 WP_248050981.1 1684666..1686903(-) (comEC/celB) [Streptococcus iners strain 29887]
MSRSIKLPCQSIHLAVLAVAVYFVVHSFSLLTMGLLSLLLVVFWFRQGKTVFLRTLPLLALCGLFFCYQKVQWERADRSA
PSHVEQVQLIPDTININGDSLSFRGRADGQTYQVFYKLASQEEQTYFQKLTDLVWLEVEAEVSLPAGQRNFKGFDYQAYL
KTQGIYRTVTITAIKKISPVQSWNVFDWLSSGRRQALVYIKTNFPAPMSHYMTGLLFGELDSDFDQMSDLYSSLGIIHLF
ALSGMQVGFFIDKFRWILLRLGLTKETVDKLQIPFSLVYAGLTGFSVSVVRSLVQKILGNMGLRKLDNFAVTVFVCLLIL
PRFLLTAGGVLTFTYAFLLTVFDFEDLGQVKKAAVESLSISLGILPVLMTYFYAFQPLSILLTFAFSFVFDVLLLPGLSV
IFLLSPLVKITWVNGFFVLMEKIIVWVADLGLRPWILGQPSGVILVLLLVCLFLLYDFHRKKKWLLGLSLVLALLFFITK
HPLENEVTVVDIGQGDSIFLRDMRGRTALIDVGGRVDFAAKEEWQERSSQANAERTLIPYLHSRGVDRIDSLVLTHTDTD
HVGDVLEVAKQVQIGRIVVSPGSLTVPDFVATLKKINVPVHVVKVGDRLPMFDAYLEVLYPDGTGDGGNNDSIVLYGRLL
ETNFLFTGDLEQGELDLIKAYPRLPVDVLKAGHHGSKGSSYPEFLDHIGAKIALVSAGENNRYKHPHQETLDRFDSRNIQ
VYRTDQQGAIRFRGWKEWTIETVRE

Nucleotide


Download         Length: 2238 bp        

>NTDB_id=794745 PW252_RS08190 WP_248050981.1 1684666..1686903(-) (comEC/celB) [Streptococcus iners strain 29887]
ATGTCACGGTCGATTAAGCTCCCCTGCCAGTCCATCCACTTGGCAGTATTGGCGGTGGCGGTCTATTTTGTAGTCCACTC
GTTTTCCCTCTTGACAATGGGCCTGCTGAGTCTGTTACTAGTTGTCTTTTGGTTTCGGCAAGGTAAGACGGTTTTCCTCA
GAACGCTGCCGCTTCTAGCCTTGTGTGGTCTGTTTTTCTGCTACCAAAAGGTCCAATGGGAGCGAGCAGATCGGTCAGCC
CCCAGCCATGTCGAACAGGTCCAGCTGATTCCCGACACCATCAATATAAACGGGGACAGCCTGTCCTTCCGCGGTCGGGC
TGACGGACAAACCTATCAGGTGTTCTACAAATTAGCCAGTCAGGAGGAGCAGACTTATTTTCAAAAGTTGACAGATTTGG
TCTGGCTTGAAGTGGAAGCAGAGGTCAGCCTGCCAGCAGGTCAGCGGAATTTCAAGGGCTTTGATTATCAGGCCTATCTG
AAAACACAGGGGATTTATCGGACAGTCACGATTACGGCGATAAAAAAGATTTCCCCAGTCCAGTCTTGGAATGTCTTTGA
CTGGCTGTCAAGCGGGAGGAGGCAGGCCTTGGTCTATATCAAAACCAACTTTCCAGCTCCTATGAGCCACTACATGACAG
GGCTTTTGTTTGGGGAGCTGGATAGTGATTTCGACCAGATGAGTGACCTCTATTCTAGTCTAGGAATCATTCATCTCTTT
GCCCTGTCAGGTATGCAGGTTGGATTTTTCATCGATAAGTTTCGCTGGATTTTACTGCGTTTGGGCTTGACCAAGGAAAC
GGTTGATAAATTACAAATTCCCTTTTCCCTTGTCTATGCGGGCTTAACTGGCTTTTCTGTGTCGGTTGTGCGGTCCTTGG
TCCAGAAAATTCTGGGTAATATGGGCTTGCGGAAGCTGGATAACTTTGCGGTGACGGTCTTTGTCTGTCTGCTGATTCTG
CCCCGATTTCTGCTGACAGCTGGCGGTGTCCTGACATTTACCTATGCTTTTTTGCTGACGGTTTTTGATTTTGAGGACTT
GGGGCAGGTCAAAAAGGCTGCGGTGGAGAGCCTCAGTATTTCACTGGGAATTTTGCCGGTACTTATGACCTATTTCTATG
CCTTTCAGCCGTTGTCTATCCTCCTGACCTTTGCCTTTTCCTTTGTCTTTGATGTCCTGCTCTTGCCAGGCTTGTCGGTC
ATTTTTCTTCTATCGCCCTTGGTTAAGATTACTTGGGTCAACGGATTTTTCGTCTTGATGGAAAAAATCATTGTCTGGGT
GGCGGATTTGGGCTTGCGACCTTGGATACTGGGCCAGCCGTCTGGGGTAATTCTTGTTCTCTTGCTGGTCTGTCTCTTCT
TACTTTACGATTTCCACAGGAAAAAGAAATGGCTCTTAGGACTGAGCTTGGTCCTCGCTCTGCTATTTTTCATAACCAAA
CACCCGCTGGAAAACGAGGTGACGGTGGTGGACATCGGGCAGGGGGACAGCATCTTTTTGCGGGATATGCGGGGACGGAC
GGCTCTGATTGATGTAGGCGGTCGGGTCGATTTTGCGGCTAAGGAGGAGTGGCAGGAGCGGTCTTCGCAGGCAAATGCAG
AGCGGACCTTGATTCCCTATCTGCATAGTCGAGGTGTGGATAGGATTGATAGTCTAGTGCTGACTCACACCGATACGGAC
CATGTGGGCGATGTGCTGGAAGTAGCTAAGCAGGTTCAGATTGGTCGGATTGTCGTGTCGCCGGGAAGTCTGACGGTACC
TGACTTTGTAGCAACTCTGAAAAAAATCAATGTGCCTGTCCATGTGGTAAAAGTGGGCGACCGCCTGCCGATGTTTGACG
CCTATCTGGAGGTCCTCTATCCAGACGGGACAGGCGACGGTGGCAATAATGATTCCATTGTCCTTTACGGTCGCTTGTTG
GAAACCAATTTTCTCTTTACAGGGGACTTGGAGCAAGGGGAGCTGGACTTGATAAAAGCTTATCCGCGACTACCTGTCGA
TGTCCTCAAAGCTGGTCACCATGGCTCCAAAGGTTCTTCCTATCCTGAATTTTTAGACCATATCGGTGCCAAGATTGCCC
TGGTATCAGCTGGAGAAAATAACCGCTACAAGCATCCCCACCAAGAAACCTTGGACCGCTTTGACAGTCGGAATATCCAA
GTCTATCGTACCGACCAGCAAGGAGCCATTCGTTTCCGAGGTTGGAAGGAGTGGACGATTGAGACGGTGAGGGAGTGA

Domains

Predicted by InterproScan.

Metallo-beta-lactamase superfamily (Lactamase_B)

(493-698)

Domain of unknown function (DUF4131) (DUF4131)

(30-175)

Competence protein (Competence)

(215-460)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEC/celB Streptococcus mitis SK321

54.485

100

0.546
  comEC/celB Streptococcus mitis NCTC 12261

53.774

99.597

0.536
  comEC/celB Streptococcus pneumoniae TIGR4

52.624

99.732

0.525
  comEC/celB Streptococcus pneumoniae Rx1

52.355

99.732

0.522
  comEC/celB Streptococcus pneumoniae D39

52.355

99.732

0.522
  comEC/celB Streptococcus pneumoniae R6

52.355

99.732

0.522
  comEC Lactococcus lactis subsp. cremoris KW2

49.064

100

0.493