Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   PVE41_RS06065 Genome accession   NZ_CP118438
Coordinates   1261265..1262491 (+) Length   408 a.a.
NCBI ID   WP_011079549.1    Uniprot ID   A0A3Q0L406
Organism   Vibrio vulnificus strain 1908-10     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1256265..1267491
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PVE41_RS06045 (PVE41_06045) ampD 1257324..1257896 (-) 573 WP_072608922.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -
  PVE41_RS06050 (PVE41_06050) nadC 1257989..1258876 (+) 888 WP_072608923.1 carboxylating nicotinate-nucleotide diphosphorylase -
  PVE41_RS06055 (PVE41_06055) pilA 1259099..1259524 (+) 426 WP_072608924.1 pilin Machinery gene
  PVE41_RS06060 (PVE41_06060) pilB 1259529..1261217 (+) 1689 WP_080538712.1 type IV-A pilus assembly ATPase PilB Machinery gene
  PVE41_RS06065 (PVE41_06065) pilC 1261265..1262491 (+) 1227 WP_011079549.1 type II secretion system F family protein Machinery gene
  PVE41_RS06070 (PVE41_06070) pilD 1262585..1263454 (+) 870 WP_131069647.1 A24 family peptidase Machinery gene
  PVE41_RS06075 (PVE41_06075) coaE 1263456..1264064 (+) 609 WP_039554617.1 dephospho-CoA kinase -
  PVE41_RS06080 (PVE41_06080) zapD 1264097..1264837 (+) 741 WP_011079546.1 cell division protein ZapD -
  PVE41_RS06085 (PVE41_06085) yacG 1264900..1265094 (+) 195 WP_026060801.1 DNA gyrase inhibitor YacG -
  PVE41_RS06090 (PVE41_06090) rplS 1265319..1265672 (-) 354 WP_011079544.1 50S ribosomal protein L19 -
  PVE41_RS06095 (PVE41_06095) trmD 1265714..1266463 (-) 750 WP_011079543.1 tRNA (guanosine(37)-N1)-methyltransferase TrmD -
  PVE41_RS06100 (PVE41_06100) rimM 1266491..1267039 (-) 549 WP_011079542.1 ribosome maturation factor RimM -
  PVE41_RS06105 (PVE41_06105) rpsP 1267055..1267303 (-) 249 WP_011079541.1 30S ribosomal protein S16 -

Sequence

Protein


Download         Length: 408 a.a.        Molecular weight: 45253.58 Da        Isoelectric Point: 10.3569

>NTDB_id=792527 PVE41_RS06065 WP_011079549.1 1261265..1262491(+) (pilC) [Vibrio vulnificus strain 1908-10]
MKLKTHSQIKNYQWKGINGAGKKVSGNTLALTELEVRDKLKMQHIQIKKIKKSSVSVFTRLSHKVKGKDITLLTRQLATM
LTTGVPILQSLKLVADNHRKAEMKSILANVSKAVEAGTPLSKALRSASPQFDGIYVDLVATGEQSGNLDQVFERLAFYRE
KNEQLRAKVIKALIYPCMVVLVALGVSYLMLTKVIPEFRKMFTGFGAELPWFTQKVLDLSDFVQAYSSWFFITLFSAIYL
LRGLSKKSPAFRLKMSRLSLKIPVIGGVLSKAAIAKFSRTLATSFSAGIPILTSLKTTSKTAGNLHYQYAIEDVYRDTAA
GMPMYIAMRNSLAFPELVLQMVMIGEESGQMDDMLNKIATIYEFEVDNTVDNLGKILEPLIIVFLGVVVGGLVTAMYLPI
FNLMSVLG

Nucleotide


Download         Length: 1227 bp        

>NTDB_id=792527 PVE41_RS06065 WP_011079549.1 1261265..1262491(+) (pilC) [Vibrio vulnificus strain 1908-10]
ATGAAGCTTAAAACCCATTCACAAATCAAAAACTATCAATGGAAAGGGATTAACGGAGCTGGAAAAAAAGTTTCCGGCAA
CACGCTGGCGCTCACCGAGCTTGAAGTGCGTGATAAGCTGAAAATGCAGCATATCCAGATCAAAAAGATCAAAAAATCCA
GTGTGTCAGTTTTCACGAGGTTAAGCCATAAAGTCAAAGGCAAAGACATCACACTGCTTACCCGCCAACTCGCCACCATG
CTGACCACTGGTGTCCCTATTCTCCAATCACTTAAATTGGTTGCTGACAACCATCGCAAAGCCGAGATGAAGTCGATTTT
AGCCAATGTGAGCAAAGCCGTTGAAGCGGGCACGCCGTTATCCAAAGCGCTTCGCAGTGCCAGCCCACAATTCGATGGCA
TTTATGTTGACTTAGTCGCCACTGGTGAACAATCGGGTAATCTTGATCAAGTTTTTGAACGTCTCGCTTTTTATCGGGAA
AAAAATGAGCAGTTGCGAGCAAAAGTGATCAAGGCGCTAATTTATCCCTGCATGGTCGTGCTGGTCGCGTTGGGCGTCTC
TTATTTAATGCTGACCAAGGTTATTCCCGAGTTTCGCAAAATGTTCACCGGATTCGGCGCAGAACTGCCTTGGTTTACGC
AAAAAGTCTTAGACCTGTCTGATTTTGTGCAAGCCTACAGCAGTTGGTTTTTCATTACGTTGTTCAGCGCTATCTATTTA
CTTCGCGGTCTAAGCAAAAAATCACCCGCATTTCGCTTAAAAATGTCACGCTTGAGTTTAAAGATCCCTGTGATTGGTGG
GGTCTTATCCAAAGCGGCGATTGCCAAATTTAGCCGCACATTGGCCACCAGTTTCAGTGCAGGTATCCCGATCCTCACCA
GTTTAAAAACCACCAGTAAAACCGCTGGCAATCTGCATTACCAATATGCGATTGAAGATGTTTATCGTGACACCGCAGCC
GGGATGCCAATGTACATCGCCATGCGCAACAGCCTTGCCTTCCCAGAATTGGTGCTGCAAATGGTGATGATCGGTGAAGA
ATCTGGCCAAATGGACGATATGCTCAACAAAATTGCCACCATCTATGAGTTTGAAGTGGATAACACCGTCGACAACCTCG
GTAAAATTCTCGAGCCGTTGATCATCGTCTTTCTGGGCGTTGTCGTCGGCGGATTGGTCACCGCAATGTACTTGCCGATC
TTTAATTTAATGAGTGTTCTGGGATAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(74-196)

Type II secretion system (T2SS), protein F (T2SSF)

(277-399)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A3Q0L406

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Vibrio cholerae strain A1552

78.5

98.039

0.77
  pilC Vibrio campbellii strain DS40M4

74.813

98.284

0.735
  pilC Pseudomonas stutzeri DSM 10701

41.584

99.02

0.412
  pilG Neisseria gonorrhoeae MS11

41.045

98.529

0.404
  pilC Acinetobacter baumannii D1279779

40

100

0.402
  pilG Neisseria meningitidis 44/76-A

40.796

98.529

0.402
  pilC Acinetobacter baylyi ADP1

40.852

97.794

0.4
  pilC Legionella pneumophila strain ERS1305867

40.099

99.02

0.397