Detailed information NTG0780037

Bioinformatically predicted

Overview

• Name: comYB
• Type: Machinery gene
• Locus tag: PND17_RS04590
• Genome accession: NZ_CP116772
• Coordinates: 861404..862504 (+)
• Length: 366 a.a.
• NCBI ID: WP_157659050.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus strain strain TSGB 4141
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 856404..867504

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
PND17_RS04580 (PND17_04580)	-	860138..860500 (+)	363	WP_087010198.1	DUF1033 family protein	-
PND17_RS04585 (PND17_04585)	comGA/cglA/cilD	860581..861522 (+)	942	WP_022096896.1	competence type IV pilus ATPase ComGA	Machinery gene
PND17_RS04590 (PND17_04590)	comYB	861404..862504 (+)	1101	WP_157659050.1	competence type IV pilus assembly protein ComGB	Machinery gene
PND17_RS04595 (PND17_04595)	comYC	862501..862827 (+)	327	WP_002946126.1	competence type IV pilus major pilin ComGC	Machinery gene
PND17_RS04600 (PND17_04600)	comYD	862787..863215 (+)	429	WP_011226626.1	competence type IV pilus minor pilin ComGD	Machinery gene
PND17_RS04605 (PND17_04605)	comGE	863187..863480 (+)	294	WP_011226625.1	competence type IV pilus minor pilin ComGE	-
PND17_RS04610 (PND17_04610)	comYF	863464..863901 (+)	438	WP_022096897.1	competence type IV pilus minor pilin ComGF	Machinery gene
PND17_RS04615 (PND17_04615)	comGG	863879..864196 (+)	318	WP_002952035.1	competence type IV pilus minor pilin ComGG	-
PND17_RS04620 (PND17_04620)	comYH	864241..865197 (+)	957	WP_011226622.1	class I SAM-dependent methyltransferase	Machinery gene
PND17_RS04625 (PND17_04625)	-	865253..866446 (+)	1194	WP_271298286.1	acetate kinase	-
PND17_RS04630 (PND17_04630)	-	866695..866892 (+)	198	WP_002885716.1	helix-turn-helix transcriptional regulator	-

Sequence

Protein

• Length: 366 a.a.
• Molecular weight: 41827.94 Da
• Isoelectric Point: 10.1084

>NTDB_id=780037 PND17_RS04590 WP_157659050.1 861404..862504(+) (comYB) [Streptococcus thermophilus strain strain TSGB 4141]
MPEKISKTIRRPTGISSWKVWLNKDVSLRGISKGKKLKISQQVKVIQLFKQLLKAGFTLTEIVAFLERSHLLKEASLSLM
KESLIRGDRLDQMLALVGFSDNIVTQISLADKHGNLLGSLTKIETYMLRMTKVRKKLMEVTTYPILLLGFLILIMLGLKN
YLLPQLLEGDGKNNWAVQLVQIFPQLFFVSLCGLLVLGLILYLWVKRQSALVFYRRMAKIPFIGQTVRLYTTAYYAREWG
NLLGQGVDLLDLVALMQEQKSKLFRELGADLEEALMLGQSFPERIASHPFFTKELSLIIAYGEANARLGYELEVYAEEVW
QNFFNRLNKATTFVQPLIFVIVAVVIVMIYVAMLLPMYQNMEGMMS

Nucleotide

• Length: 1101 bp

>NTDB_id=780037 PND17_RS04590 WP_157659050.1 861404..862504(+) (comYB) [Streptococcus thermophilus strain strain TSGB 4141]
TTGCCAGAGAAAATTTCCAAAACCATTCGTCGACCAACTGGAATCAGCAGTTGGAAGGTTTGGTTAAACAAGGATGTCTC
ACTGAGAGGGATATCCAAGGGGAAAAAATTAAAGATTAGTCAGCAAGTTAAGGTTATCCAGCTCTTCAAACAACTTTTAA
AGGCCGGTTTTACCTTAACTGAAATCGTAGCCTTTTTGGAGCGAAGTCACTTGCTGAAAGAAGCATCCTTGTCTCTTATG
AAAGAGAGTTTAATACGCGGTGATAGGTTGGATCAGATGTTAGCGTTAGTAGGGTTTTCGGACAATATTGTTACTCAGAT
TTCTCTTGCTGACAAGCACGGTAATCTTCTAGGGAGTCTAACAAAGATTGAAACCTATATGCTTCGTATGACAAAGGTTC
GCAAGAAACTCATGGAGGTGACGACTTATCCCATACTACTTCTGGGTTTTCTGATTCTGATTATGCTAGGACTTAAAAAT
TATCTTCTACCCCAACTCTTAGAGGGTGATGGTAAGAATAATTGGGCTGTACAGTTGGTTCAAATTTTTCCCCAGCTTTT
TTTTGTGAGTTTGTGTGGACTCCTTGTGTTGGGTTTAATTCTCTATCTATGGGTGAAACGACAGTCAGCCCTTGTTTTTT
ATAGGCGAATGGCCAAAATCCCTTTTATTGGTCAGACAGTAAGGCTTTACACGACCGCCTATTATGCTAGGGAATGGGGA
AATTTATTAGGTCAAGGCGTTGATTTGCTAGATTTGGTGGCTCTTATGCAAGAGCAAAAGTCTAAACTCTTCCGTGAGCT
GGGAGCCGATTTGGAAGAAGCCCTGATGCTGGGACAGAGTTTTCCTGAACGTATTGCCAGTCATCCGTTTTTTACTAAGG
AGCTCTCACTAATTATTGCTTATGGGGAGGCCAATGCGAGGTTGGGCTATGAGTTGGAAGTTTATGCCGAGGAGGTTTGG
CAAAACTTCTTTAACCGTCTTAATAAGGCAACAACCTTTGTGCAACCCCTCATTTTTGTTATTGTTGCAGTTGTGATTGT
AATGATCTATGTAGCCATGCTATTACCAATGTATCAAAATATGGAAGGAATGATGTCATGA

Domains

Predicted by InterproScan.

• Type II secretion system (T2SS), protein F (T2SSF) (236-356)

• Type II secretion system (T2SS), protein F (T2SSF) (51-164)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYB	Streptococcus mutans UA140	54.678	93.443	0.511
comYB	Streptococcus mutans UA159	54.678	93.443	0.511
comYB	Streptococcus gordonii str. Challis substr. CH1	50.877	93.443	0.475
comGB/cglB	Streptococcus mitis NCTC 12261	50.151	90.437	0.454
comGB/cglB	Streptococcus mitis SK321	49.394	90.164	0.445
comGB/cglB	Streptococcus pneumoniae Rx1	49.39	89.617	0.443
comGB/cglB	Streptococcus pneumoniae D39	49.39	89.617	0.443
comGB/cglB	Streptococcus pneumoniae R6	49.39	89.617	0.443
comGB/cglB	Streptococcus pneumoniae TIGR4	49.39	89.617	0.443
comGB	Lactococcus lactis subsp. cremoris KW2	45.455	90.164	0.41