Detailed information    

insolico Bioinformatically predicted

Overview


Name   comYF   Type   Machinery gene
Locus tag   PND17_RS04610 Genome accession   NZ_CP116772
Coordinates   863464..863901 (+) Length   145 a.a.
NCBI ID   WP_022096897.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain strain TSGB 4141     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context


Location: 858464..868901
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PND17_RS04580 (PND17_04580) - 860138..860500 (+) 363 WP_087010198.1 DUF1033 family protein -
  PND17_RS04585 (PND17_04585) comGA/cglA/cilD 860581..861522 (+) 942 WP_022096896.1 competence type IV pilus ATPase ComGA Machinery gene
  PND17_RS04590 (PND17_04590) comYB 861404..862504 (+) 1101 WP_157659050.1 competence type IV pilus assembly protein ComGB Machinery gene
  PND17_RS04595 (PND17_04595) comYC 862501..862827 (+) 327 WP_002946126.1 competence type IV pilus major pilin ComGC Machinery gene
  PND17_RS04600 (PND17_04600) comYD 862787..863215 (+) 429 WP_011226626.1 competence type IV pilus minor pilin ComGD Machinery gene
  PND17_RS04605 (PND17_04605) comGE 863187..863480 (+) 294 WP_011226625.1 competence type IV pilus minor pilin ComGE -
  PND17_RS04610 (PND17_04610) comYF 863464..863901 (+) 438 WP_022096897.1 competence type IV pilus minor pilin ComGF Machinery gene
  PND17_RS04615 (PND17_04615) comGG 863879..864196 (+) 318 WP_002952035.1 competence type IV pilus minor pilin ComGG -
  PND17_RS04620 (PND17_04620) comYH 864241..865197 (+) 957 WP_011226622.1 class I SAM-dependent methyltransferase Machinery gene
  PND17_RS04625 (PND17_04625) - 865253..866446 (+) 1194 WP_271298286.1 acetate kinase -
  PND17_RS04630 (PND17_04630) - 866695..866892 (+) 198 WP_002885716.1 helix-turn-helix transcriptional regulator -
  PND17_RS04635 (PND17_04635) - 867135..867560 (+) 426 WP_271298285.1 CPBP family intramembrane glutamic endopeptidase -
  PND17_RS04640 (PND17_04640) - 867634..868077 (+) 444 WP_002946118.1 hypothetical protein -
  PND17_RS04645 (PND17_04645) - 868180..868842 (+) 663 WP_011227583.1 CPBP family intramembrane glutamic endopeptidase -

Sequence


Protein


Download         Length: 145 a.a.        Molecular weight: 16375.89 Da        Isoelectric Point: 8.9784

>NTDB_id=780040 PND17_RS04610 WP_022096897.1 863464..863901(+) (comYF) [Streptococcus thermophilus strain strain TSGB 4141]
MYLSSKLRAFTLLECLVALLVIAGSVQVYQGLTTVLVSNVKQVRQQENQDWLLFVQQMEAELEGCQLVKVEGNKLYVKKD
NQDLAFGLSSASDFRKTNADGRGYQPMLFDVKSSKVSQKNQIVTIQVTLKNELQRSFVYAFEKTG

Nucleotide


Download         Length: 438 bp        

>NTDB_id=780040 PND17_RS04610 WP_022096897.1 863464..863901(+) (comYF) [Streptococcus thermophilus strain strain TSGB 4141]
ATGTATCTAAGCAGTAAGCTGCGTGCCTTTACCCTCTTGGAATGTCTAGTGGCCTTGTTGGTCATTGCTGGCTCAGTTCA
AGTTTATCAAGGGTTAACCACTGTACTTGTGAGTAATGTTAAGCAGGTAAGACAACAAGAAAACCAAGATTGGCTTCTAT
TTGTTCAACAAATGGAGGCAGAATTAGAAGGATGTCAGTTGGTCAAGGTAGAGGGGAACAAACTCTATGTCAAGAAGGAT
AATCAAGACTTGGCTTTTGGTCTTTCAAGTGCCTCTGATTTTCGAAAAACAAATGCTGATGGTCGAGGTTATCAACCAAT
GCTTTTCGATGTCAAATCTAGTAAGGTAAGTCAAAAGAACCAGATAGTTACCATCCAAGTGACTCTTAAAAATGAACTAC
AAAGGAGTTTTGTTTATGCTTTTGAAAAAACAGGTTAG


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYF Streptococcus mutans UA140

58.865

97.241

0.572

  comYF Streptococcus mutans UA159

58.156

97.241

0.566

  comGF/cglF Streptococcus pneumoniae D39

48.571

96.552

0.469

  comGF/cglF Streptococcus pneumoniae Rx1

48.571

96.552

0.469

  comGF/cglF Streptococcus pneumoniae R6

48.571

96.552

0.469

  comGF/cglF Streptococcus pneumoniae TIGR4

48.571

96.552

0.469

  comGF/cglF Streptococcus mitis NCTC 12261

46.809

97.241

0.455

  comGF/cglF Streptococcus mitis SK321

46.099

97.241

0.448

  comGF Lactococcus lactis subsp. cremoris KW2

46.043

95.862

0.441