Detailed information NTG0779749

Bioinformatically predicted

Overview

• Name: comGA
• Type: Machinery gene
• Locus tag: QYM42_RS11900
• Genome accession: NZ_CP129526
• Coordinates: 2360373..2361311 (-)
• Length: 312 a.a.
• NCBI ID: WP_058206479.1
• Uniprot ID: -
• Organism: Lactococcus lactis strain ZZ-2
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2355373..2366311

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QYM42_RS11870 (QYM42_11870)	-	2355910..2356464 (+)	555	WP_251899969.1	helix-turn-helix domain-containing protein	-
QYM42_RS11875 (QYM42_11875)	-	2356475..2357062 (+)	588	WP_251899970.1	hypothetical protein	-
QYM42_RS11880 (QYM42_11880)	-	2357124..2357675 (+)	552	WP_301675294.1	hypothetical protein	-
QYM42_RS11885 (QYM42_11885)	-	2357798..2359255 (+)	1458	WP_301675295.1	recombinase family protein	-
QYM42_RS11890 (QYM42_11890)	-	2359252..2359392 (-)	141	WP_228248618.1	hypothetical protein	-
QYM42_RS11895 (QYM42_11895)	comGB	2359406..2360425 (-)	1020	WP_047206974.1	competence type IV pilus assembly protein ComGB	Machinery gene
QYM42_RS11900 (QYM42_11900)	comGA	2360373..2361311 (-)	939	WP_058206479.1	competence type IV pilus ATPase ComGA	Machinery gene

Sequence

Protein

• Length: 312 a.a.
• Molecular weight: 35649.84 Da
• Isoelectric Point: 6.1811

>NTDB_id=779749 QYM42_RS11900 WP_058206479.1 2360373..2361311(-) (comGA) [Lactococcus lactis strain ZZ-2]
MIPKMAKELIQRAIDRGASDIYLIASKEKYKLYFRQMTARDLVEEIGLEVGLALLTHFKFLAGMNTGERRRVQLGACWYE
LEESNAKRLRLSTVGDFEGNESLVIRLLHDQNKELDFWFDEELENYDCKRGLHLFAGPVGSGKTSLMFDLARRHFTDLQV
ITIEEPVELIDSDFIQLQVNEVIGNSYDELIKLSLRHRPDLLIVGEIRDKLTAQAVLRASLTGYTVFSTVHASSVRGVIQ
RLSELGLSHWEIKNALSSVVYQRLIAGKGVLDIAKNEFESWSSENWNKKIDQLLTNGYLTPTEAKREKIKTD

Nucleotide

• Length: 939 bp

>NTDB_id=779749 QYM42_RS11900 WP_058206479.1 2360373..2361311(-) (comGA) [Lactococcus lactis strain ZZ-2]
ATGATACCAAAAATGGCAAAAGAATTAATTCAAAGAGCAATTGATAGAGGTGCATCAGATATTTATCTGATTGCTTCAAA
AGAAAAGTATAAACTTTATTTTCGACAAATGACAGCACGTGATCTGGTAGAAGAAATTGGGTTAGAAGTTGGCTTAGCAC
TACTTACTCACTTTAAGTTTCTAGCTGGGATGAATACAGGAGAACGCAGACGAGTTCAATTGGGAGCTTGTTGGTATGAA
TTAGAGGAAAGTAATGCAAAACGTTTGCGTCTTTCAACAGTGGGGGATTTCGAGGGTAATGAATCTTTAGTAATACGTCT
CTTGCATGATCAAAACAAAGAACTTGATTTTTGGTTTGATGAAGAGCTAGAGAATTATGATTGTAAAAGAGGATTGCATC
TCTTTGCCGGTCCAGTAGGCTCGGGAAAAACATCTTTAATGTTTGATTTAGCTCGTCGTCATTTTACAGATTTACAAGTT
ATCACTATTGAAGAACCCGTTGAGTTGATTGATTCCGATTTTATTCAGTTACAAGTCAACGAAGTCATTGGTAATAGTTA
TGATGAATTAATTAAATTATCACTGAGGCATCGCCCAGATTTGTTAATCGTTGGTGAAATTCGTGATAAATTGACCGCTC
AAGCAGTTTTACGGGCTAGTTTGACAGGTTATACAGTGTTTTCAACCGTTCATGCCTCTTCTGTTAGAGGTGTCATTCAG
AGACTATCAGAGCTGGGTTTAAGTCATTGGGAAATAAAAAATGCTTTATCAAGTGTTGTTTATCAGCGTTTAATAGCTGG
GAAAGGAGTATTAGACATTGCCAAAAACGAATTTGAGTCTTGGTCATCAGAAAATTGGAATAAAAAAATTGATCAGCTAC
TTACAAATGGATATCTCACACCTACTGAAGCCAAAAGGGAAAAAATTAAGACTGATTAA

Domains

Predicted by InterProScan.

• Type II/IV secretion system protein (T2SSE) (9-265)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGA	Lactococcus lactis subsp. cremoris KW2	77.244	100	0.772
comGA/cglA	Streptococcus sobrinus strain NIDR 6715-7	54.984	99.679	0.548
comGA/cglA/cilD	Streptococcus mitis NCTC 12261	53.698	99.679	0.535
comGA/cglA/cilD	Streptococcus pneumoniae Rx1	52.733	99.679	0.526
comGA/cglA/cilD	Streptococcus pneumoniae D39	52.733	99.679	0.526
comGA/cglA/cilD	Streptococcus pneumoniae R6	52.733	99.679	0.526
comGA/cglA/cilD	Streptococcus pneumoniae TIGR4	52.733	99.679	0.526
comGA	Streptococcus mutans UA140	52.244	100	0.522
comGA	Streptococcus mutans UA159	52.244	100	0.522
comGA	Streptococcus gordonii str. Challis substr. CH1	51.923	100	0.519