Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   PML75_RS12305 Genome accession   NZ_CP116555
Coordinates   2595949..2597193 (-) Length   414 a.a.
NCBI ID   WP_002375502.1    Uniprot ID   -
Organism   Enterococcus faecalis strain K70-12a     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 2590949..2602193
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PML75_RS12285 (PML75_12285) - 2591419..2591805 (-) 387 WP_002359008.1 RicAFT regulatory complex protein RicA family protein -
  PML75_RS12290 (PML75_12290) - 2591879..2592676 (-) 798 WP_002354864.1 TIGR00282 family metallophosphoesterase -
  PML75_RS12295 (PML75_12295) rny 2592836..2594392 (-) 1557 WP_002354863.1 ribonuclease Y -
  PML75_RS12300 (PML75_12300) recA 2594789..2595835 (-) 1047 WP_002354860.1 recombinase RecA Machinery gene
  PML75_RS12305 (PML75_12305) cinA 2595949..2597193 (-) 1245 WP_002375502.1 competence/damage-inducible protein A Machinery gene
  PML75_RS12310 (PML75_12310) - 2597385..2598584 (+) 1200 WP_248857373.1 hypothetical protein -
  PML75_RS12315 (PML75_12315) - 2598664..2599293 (-) 630 WP_002354854.1 NAD(P)-dependent oxidoreductase -
  PML75_RS12320 (PML75_12320) - 2599352..2599777 (-) 426 WP_002383201.1 Rrf2 family transcriptional regulator -
  PML75_RS12325 (PML75_12325) - 2599866..2600249 (-) 384 WP_010712905.1 YccF domain-containing protein -
  PML75_RS12330 (PML75_12330) - 2600413..2601204 (+) 792 WP_002415619.1 hypothetical protein -

Sequence

Protein


Download         Length: 414 a.a.        Molecular weight: 45163.26 Da        Isoelectric Point: 4.6698

>NTDB_id=778231 PML75_RS12305 WP_002375502.1 2595949..2597193(-) (cinA) [Enterococcus faecalis strain K70-12a]
MKAEIIAVGTELLLGQVVNTNATFLSEELAALGIDVYYQTVVGDNGGRLETLLTEAEQRSDLIVLCGGLGPTEDDLTKQV
VAQHLHKSLVEDQEGLNRLHQFFQQSKRPMTENNLRQVLAIEGGQVLQNPTGLAVGSFVTEGATSYLLLPGPPNELIPMF
QQAARPLLIDAFPQEEQLISRVLRFYGIGESQLVTEIQSLIAHQTNPTIAPYAKPNEVTLRLTVKTKDLVAGEELLTATE
EKVLAKVGDYFYGYGDDNSLAKVTVDLLLQNGQTVTAAESLTAGLFQSTLGEIAGASKIFKGGFVTYSQETKENFLGISH
ELLEEHGTVSEACAKEMAEKARQLAKSNYGLSFTGVAGDPIEGQPTGTVWIGLAEEGQPTVAECFHFNRDRNYIRQSAVM
RGLDLLRRRIINKK

Nucleotide


Download         Length: 1245 bp        

>NTDB_id=778231 PML75_RS12305 WP_002375502.1 2595949..2597193(-) (cinA) [Enterococcus faecalis strain K70-12a]
ATGAAAGCAGAAATCATTGCAGTCGGAACAGAGTTATTACTGGGACAAGTAGTGAATACCAACGCCACCTTTTTATCAGA
AGAGTTAGCTGCGCTAGGCATCGATGTTTACTATCAGACCGTTGTTGGCGATAACGGCGGCCGCTTAGAAACGCTACTAA
CAGAAGCAGAACAAAGAAGTGATTTAATTGTCCTTTGTGGAGGGCTAGGACCTACAGAAGACGATTTAACCAAGCAAGTT
GTCGCACAACATCTCCATAAATCATTAGTAGAAGATCAAGAAGGATTGAACCGCTTGCACCAGTTTTTCCAACAGTCTAA
GCGGCCAATGACGGAAAATAATCTACGACAAGTGTTAGCCATTGAAGGTGGACAAGTTCTTCAAAACCCGACAGGATTAG
CGGTTGGTTCTTTCGTAACAGAAGGCGCAACAAGCTATTTGCTCTTACCAGGGCCGCCCAATGAATTAATTCCGATGTTC
CAACAAGCGGCACGACCTTTATTGATTGATGCGTTTCCACAAGAAGAACAATTGATTTCAAGAGTCTTGCGTTTTTATGG
GATTGGTGAATCACAGCTGGTGACCGAGATTCAATCGTTGATTGCTCACCAAACGAATCCAACCATTGCGCCTTATGCTA
AGCCTAATGAAGTGACACTTCGTTTAACAGTTAAAACAAAAGACTTAGTAGCTGGCGAAGAATTATTAACAGCGACGGAA
GAAAAGGTTTTAGCTAAAGTGGGAGACTATTTTTATGGGTATGGGGATGACAATAGTTTAGCCAAGGTAACAGTGGATTT
GTTATTACAAAACGGACAAACCGTCACGGCTGCTGAGAGCCTCACCGCTGGCCTATTCCAAAGTACACTGGGGGAAATTG
CGGGCGCTTCGAAGATTTTTAAGGGAGGCTTCGTGACGTATTCGCAAGAAACAAAAGAGAACTTTTTAGGGATTTCTCAT
GAACTTTTAGAAGAACATGGCACGGTAAGTGAAGCGTGTGCCAAAGAAATGGCAGAGAAAGCGCGTCAGTTAGCTAAATC
TAACTATGGTTTATCATTTACTGGGGTCGCTGGTGACCCAATCGAAGGTCAACCGACAGGCACTGTTTGGATTGGGCTGG
CGGAAGAAGGCCAACCAACTGTTGCAGAATGTTTCCATTTTAACCGTGACCGAAATTATATTAGACAGAGTGCGGTTATG
CGAGGGTTAGATCTTTTGCGACGCCGAATCATTAATAAAAAATAA

Domains

Predicted by InterproScan.

Probable molybdopterin binding domain (MoCF_biosynth)

(5-168)

Competence-damaged protein (CinA)

(258-409)

Damage-inducible protein CinA KH domain (CinA_KH)

(180-253)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mutans UA159

52.392

100

0.529
  cinA Streptococcus mitis SK321

51.537

100

0.527
  cinA Streptococcus mitis NCTC 12261

51.3

100

0.524
  cinA Streptococcus pneumoniae TIGR4

50.591

100

0.517
  cinA Streptococcus pneumoniae D39

50.355

100

0.514
  cinA Streptococcus pneumoniae R6

50.118

100

0.512
  cinA Streptococcus pneumoniae Rx1

50.118

100

0.512
  cinA Bacillus subtilis subsp. subtilis str. 168

48.522

98.068

0.476
  cinA Streptococcus suis isolate S10

44.039

99.275

0.437