Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   PCP57_RS09330 Genome accession   NZ_CP115287
Coordinates   2011287..2012504 (-) Length   405 a.a.
NCBI ID   WP_003161763.1    Uniprot ID   A0A3P3S6C0
Organism   Pseudomonas aeruginosa strain F006     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2006287..2017504
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PCP57_RS09285 (PCP57_09290) - 2006471..2006920 (-) 450 WP_033970456.1 MOSC domain-containing protein -
  PCP57_RS09290 (PCP57_09295) - 2006917..2007546 (-) 630 WP_003094668.1 DUF1780 domain-containing protein -
  PCP57_RS09295 (PCP57_09300) - 2007679..2008104 (+) 426 WP_033976385.1 GNAT family N-acetyltransferase -
  PCP57_RS09300 (PCP57_09305) - 2008101..2008571 (+) 471 WP_328994901.1 FAD/FMN-containing dehydrogenase -
  PCP57_RS09305 (PCP57_09310) - 2008568..2009257 (+) 690 WP_031805639.1 energy-coupling factor ABC transporter permease -
  PCP57_RS09310 (PCP57_09315) - 2009363..2009572 (+) 210 WP_003094660.1 hypothetical protein -
  PCP57_RS09315 (PCP57_09320) yacG 2009609..2009809 (-) 201 WP_003094656.1 DNA gyrase inhibitor YacG -
  PCP57_RS09320 (PCP57_09325) coaE 2009806..2010417 (-) 612 WP_033970460.1 dephospho-CoA kinase -
  PCP57_RS09325 (PCP57_09330) pilD 2010414..2011286 (-) 873 WP_114232522.1 type IV prepilin peptidase/methyltransferase PilD Machinery gene
  PCP57_RS09330 (PCP57_09335) pilC 2011287..2012504 (-) 1218 WP_003161763.1 type II secretion system F family protein Machinery gene
  PCP57_RS09335 (PCP57_09340) pilB 2012508..2014208 (-) 1701 WP_328994906.1 type IV-A pilus assembly ATPase PilB Machinery gene
  PCP57_RS09340 (PCP57_09345) - 2014439..2014903 (+) 465 WP_328994908.1 pilin -
  PCP57_RS09345 (PCP57_09350) - 2014977..2016371 (+) 1395 WP_328994910.1 O-antigen ligase family protein -
  PCP57_RS09355 (PCP57_09360) nadC 2016552..2017400 (-) 849 WP_034071563.1 carboxylating nicotinate-nucleotide diphosphorylase -

Sequence

Protein


Download         Length: 405 a.a.        Molecular weight: 43998.80 Da        Isoelectric Point: 9.8103

>NTDB_id=771344 PCP57_RS09330 WP_003161763.1 2011287..2012504(-) (pilC) [Pseudomonas aeruginosa strain F006]
MADKALKTSVFVWEGTDKKGTKVKGELSSQNPTLVKAQLRKQGITPVKVRKKGISLLGAGKKIKPMDIALFTRQMSTMMA
AGVPLLQSFDIISEGFDNPNMRKLVEEIKQEVAGGNSLANSLRKKPQYFDSLYCNLVDAGEQSGALETLLDRVATYKEKT
EALKAKIKKAMTYPIAVIVVAIIVSAILLIKVVPQFQSVFEGFGAELPAFTQMVINISNVLQEWWLLVLLMMGGAGFLLN
HAYKRSEKFRDATDRTVLKLPIVGAILYKSAVARYARTLSTTFAAGVPLVEALDSVSGATGNVVFRDAVGKIKQDVSTGM
QLNFSMRTTNIFPSMAIQMTAIGEESGALDDMLAKVAGFYEQEVDNAVDNLTALMEPMIMAVLGVLVGGLIIAMYLPIFQ
LGNVV

Nucleotide


Download         Length: 1218 bp        

>NTDB_id=771344 PCP57_RS09330 WP_003161763.1 2011287..2012504(-) (pilC) [Pseudomonas aeruginosa strain F006]
ATGGCGGACAAAGCGTTAAAGACCAGTGTCTTCGTATGGGAAGGCACTGACAAGAAAGGCACCAAGGTCAAGGGCGAGCT
GTCCAGCCAGAACCCGACCCTGGTCAAGGCGCAACTGCGCAAGCAGGGCATCACGCCGGTCAAGGTCCGCAAGAAAGGCA
TTTCCCTGCTGGGAGCGGGGAAGAAGATCAAGCCCATGGACATCGCCCTGTTCACCCGCCAGATGTCCACCATGATGGCC
GCGGGTGTGCCATTGCTGCAGTCGTTCGACATCATCAGCGAAGGCTTCGACAACCCGAACATGCGCAAGCTGGTGGAAGA
GATCAAGCAGGAGGTAGCCGGCGGCAACAGCCTGGCCAACTCGCTGCGCAAGAAGCCGCAATACTTCGACTCCCTCTACT
GCAATCTGGTGGACGCCGGCGAACAGTCCGGCGCCCTGGAAACCCTGCTCGACCGGGTCGCCACCTACAAGGAAAAGACC
GAGGCGCTGAAGGCCAAGATCAAGAAGGCCATGACCTACCCGATCGCGGTGATCGTCGTCGCCATCATCGTTTCGGCGAT
CCTACTGATCAAAGTGGTGCCGCAGTTCCAGTCGGTGTTCGAGGGCTTCGGCGCCGAACTGCCGGCCTTCACCCAAATGG
TCATCAATATCTCCAACGTGCTCCAGGAATGGTGGCTCCTGGTACTGCTGATGATGGGCGGCGCCGGCTTCCTGCTGAAC
CACGCCTACAAGCGTTCGGAGAAGTTCCGCGACGCCACCGACCGCACGGTACTGAAGCTGCCGATCGTCGGCGCCATCCT
CTACAAATCCGCCGTGGCACGCTACGCGCGGACGCTGTCGACCACCTTCGCCGCCGGCGTGCCATTGGTGGAAGCCCTTG
ACTCGGTTTCCGGCGCCACCGGCAACGTGGTGTTCAGGGACGCGGTGGGCAAGATCAAGCAGGACGTGTCCACCGGCATG
CAGCTGAACTTCTCCATGCGCACCACCAACATCTTCCCCAGCATGGCCATCCAGATGACCGCTATCGGCGAGGAATCGGG
CGCGCTGGACGACATGCTGGCCAAGGTCGCTGGCTTCTACGAGCAGGAAGTGGATAATGCCGTGGACAACCTGACCGCCC
TGATGGAACCGATGATCATGGCGGTCCTCGGGGTCCTGGTCGGTGGCCTGATCATCGCCATGTACCTGCCGATCTTCCAG
CTGGGCAACGTCGTCTAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(276-397)

Type II secretion system (T2SS), protein F (T2SSF)

(71-194)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A3P3S6C0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Pseudomonas stutzeri DSM 10701

78.765

100

0.788
  pilC Acinetobacter baylyi ADP1

61.275

100

0.617
  pilC Acinetobacter baumannii D1279779

60.644

99.753

0.605
  pilC Legionella pneumophila strain ERS1305867

54.293

97.778

0.531
  pilG Neisseria gonorrhoeae MS11

46.287

99.753

0.462
  pilG Neisseria meningitidis 44/76-A

45.771

99.259

0.454
  pilC Vibrio cholerae strain A1552

41.728

100

0.417
  pilC Vibrio campbellii strain DS40M4

40.898

99.012

0.405
  pilC Thermus thermophilus HB27

38.155

99.012

0.378