Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   O6R09_RS08845 Genome accession   NZ_CP114883
Coordinates   1746389..1747648 (-) Length   419 a.a.
NCBI ID   WP_269725633.1    Uniprot ID   -
Organism   Streptococcus alactolyticus strain LGM     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 1741389..1752648
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  O6R09_RS08815 (O6R09_08815) - 1742038..1742337 (-) 300 WP_154454978.1 DUF1292 domain-containing protein -
  O6R09_RS08820 (O6R09_08820) ruvX 1742350..1742769 (-) 420 WP_154454977.1 Holliday junction resolvase RuvX -
  O6R09_RS08825 (O6R09_08825) - 1742766..1743035 (-) 270 WP_154454976.1 IreB family regulatory phosphoprotein -
  O6R09_RS08830 (O6R09_08830) - 1743265..1744521 (+) 1257 WP_269725566.1 ISL3 family transposase -
  O6R09_RS08835 (O6R09_08835) spx 1744686..1745084 (-) 399 WP_154454975.1 transcriptional regulator Spx -
  O6R09_RS08840 (O6R09_08840) recA 1745183..1746340 (-) 1158 WP_269725632.1 recombinase RecA Machinery gene
  O6R09_RS08845 (O6R09_08845) cinA 1746389..1747648 (-) 1260 WP_269725633.1 competence/damage-inducible protein A Machinery gene
  O6R09_RS08850 (O6R09_08850) ruvA 1747700..1748293 (-) 594 WP_154454972.1 Holliday junction branch migration protein RuvA -
  O6R09_RS08855 (O6R09_08855) mutL 1748295..1750235 (-) 1941 WP_269725634.1 DNA mismatch repair endonuclease MutL -

Sequence

Protein


Download         Length: 419 a.a.        Molecular weight: 45383.54 Da        Isoelectric Point: 4.7517

>NTDB_id=767353 O6R09_RS08845 WP_269725633.1 1746389..1747648(-) (cinA) [Streptococcus alactolyticus strain LGM]
MKAELITVGTEILTGQITNTNAQFLSEEFAKLGIDVFFQTTVGDNEERLLSVIDLASQRSDLIVLCGGLGPTEDDLTKQT
LAKYLKRDLVINEEANQRLNDYFATHPQFVRTANNDRQAQLIEGATPLQNITGLAVGGLVTVDGVTYVVLPGPPSELKPM
VLNELVPLLSGHNERLYSRVLRFFGIGESQLVTVLSDLIDNQTDPTIAPYAKTGEVTLRLSTKAADEAAAKVKLDQLEQA
ILAKSTLDNVPLSELLYGYGDDNSLARVVFQLLKEHHKTITAAESLTAGLFQSTIADFSGASSVFNGGFVTYSMEEKSKL
LHIPLEDLQEHGVVSHFTAEKMAEQSRLLTGADIGIGLTGVAGPDSLEGHPAGTIFIGISTKDDCRSIHLHIGGKSRSDV
RHIATLYAFNLVRQALLDI

Nucleotide


Download         Length: 1260 bp        

>NTDB_id=767353 O6R09_RS08845 WP_269725633.1 1746389..1747648(-) (cinA) [Streptococcus alactolyticus strain LGM]
ATGAAAGCTGAACTGATTACTGTTGGAACAGAAATTTTAACAGGTCAAATTACCAACACCAATGCTCAATTTCTCTCAGA
AGAATTTGCTAAATTGGGAATTGATGTTTTTTTTCAAACTACCGTAGGTGATAACGAAGAGCGTCTGTTGTCGGTTATTG
ATTTAGCCAGTCAAAGAAGCGACCTCATCGTTTTGTGTGGTGGCTTGGGACCAACGGAAGATGATTTAACTAAACAAACT
TTGGCAAAATACCTCAAACGCGATTTGGTGATCAACGAAGAAGCCAATCAACGTTTGAATGACTATTTTGCAACGCATCC
CCAATTTGTTCGTACGGCCAACAATGACCGTCAAGCTCAGTTAATTGAGGGGGCAACGCCCTTGCAAAATATCACAGGTT
TAGCTGTGGGTGGCTTGGTAACTGTTGATGGCGTTACTTACGTCGTGCTACCAGGTCCGCCAAGTGAATTAAAACCGATG
GTCTTAAATGAATTGGTTCCTCTTTTGTCAGGACATAATGAACGCCTATATTCACGGGTTTTGCGTTTCTTTGGCATCGG
GGAAAGCCAATTGGTAACCGTTCTGTCTGACTTGATTGACAATCAAACAGACCCAACCATTGCTCCTTATGCTAAAACAG
GTGAGGTAACACTTCGTTTGTCAACAAAAGCAGCAGATGAGGCTGCCGCTAAGGTAAAATTAGACCAATTGGAACAAGCT
ATTTTGGCTAAATCAACCTTGGATAATGTCCCATTGAGTGAATTGCTTTACGGTTATGGTGATGATAATAGTTTGGCGCG
TGTGGTCTTTCAATTGCTCAAAGAACACCATAAAACCATTACAGCAGCAGAAAGTTTGACCGCAGGGCTATTTCAATCCA
CTATCGCAGACTTTTCAGGTGCCTCTTCCGTCTTTAACGGCGGTTTTGTGACATACAGCATGGAAGAAAAATCAAAATTG
TTGCACATTCCATTAGAAGATTTGCAAGAACATGGTGTGGTTAGTCACTTTACCGCTGAAAAAATGGCGGAACAATCACG
TTTGTTGACAGGTGCAGATATCGGCATTGGTTTGACTGGCGTTGCTGGTCCAGATAGTTTGGAAGGACATCCAGCAGGAA
CCATTTTTATTGGCATTTCGACAAAAGACGATTGCCGTTCGATTCATCTTCATATCGGTGGTAAAAGTCGTTCAGATGTC
CGTCATATCGCGACTTTGTACGCTTTTAACTTAGTACGTCAAGCTTTATTAGACATTTGA

Domains

Predicted by InterproScan.

Competence-damaged protein (CinA)

(263-415)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)

Damage-inducible protein CinA KH domain (CinA_KH)

(178-241)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mutans UA159

70.264

99.523

0.699
  cinA Streptococcus mitis SK321

68.9

99.761

0.687
  cinA Streptococcus mitis NCTC 12261

67.943

99.761

0.678
  cinA Streptococcus pneumoniae Rx1

66.507

99.761

0.663
  cinA Streptococcus pneumoniae TIGR4

66.507

99.761

0.663
  cinA Streptococcus pneumoniae R6

66.507

99.761

0.663
  cinA Streptococcus pneumoniae D39

66.268

99.761

0.661
  cinA Streptococcus suis isolate S10

50.721

99.284

0.504
  cinA Bacillus subtilis subsp. subtilis str. 168

48.565

99.761

0.484