Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   OQG81_RS01220 Genome accession   NZ_CP113440
Coordinates   194718..195977 (+) Length   419 a.a.
NCBI ID   WP_014295450.1    Uniprot ID   A0AA47FCN8
Organism   Streptococcus macedonicus strain E37     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 189718..200977
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OQG81_RS01185 (OQG81_01185) ruvA 191161..191754 (+) 594 WP_014295457.1 Holliday junction branch migration protein RuvA -
  OQG81_RS01190 (OQG81_01190) - 191859..192515 (-) 657 WP_014295456.1 transcriptional regulator -
  OQG81_RS01195 (OQG81_01195) - 192776..192919 (+) 144 WP_014295455.1 hypothetical protein -
  OQG81_RS01200 (OQG81_01200) - 192938..193240 (+) 303 WP_014295454.1 hypothetical protein -
  OQG81_RS01205 (OQG81_01205) - 193622..193885 (+) 264 WP_223246337.1 hypothetical protein -
  OQG81_RS01210 (OQG81_01210) - 193954..194184 (+) 231 WP_014295452.1 hypothetical protein -
  OQG81_RS01215 (OQG81_01215) - 194123..194560 (+) 438 WP_014295451.1 hypothetical protein -
  OQG81_RS01220 (OQG81_01220) cinA 194718..195977 (+) 1260 WP_014295450.1 competence/damage-inducible protein A Machinery gene
  OQG81_RS01225 (OQG81_01225) recA 196027..197181 (+) 1155 WP_265644044.1 recombinase RecA Machinery gene
  OQG81_RS01230 (OQG81_01230) spx 197450..197848 (+) 399 WP_009855164.1 transcriptional regulator Spx -
  OQG81_RS01235 (OQG81_01235) - 198170..198439 (+) 270 WP_003066890.1 IreB family regulatory phosphoprotein -
  OQG81_RS01240 (OQG81_01240) ruvX 198436..198855 (+) 420 WP_006531414.1 Holliday junction resolvase RuvX -
  OQG81_RS01245 (OQG81_01245) - 198888..199205 (+) 318 WP_006531413.1 DUF1292 domain-containing protein -

Sequence

Protein


Download         Length: 419 a.a.        Molecular weight: 45466.90 Da        Isoelectric Point: 5.3127

>NTDB_id=762273 OQG81_RS01220 WP_014295450.1 194718..195977(+) (cinA) [Streptococcus macedonicus strain E37]
MKAEIIAVGTEILTGQITNTNAQFLSEEFAKLGIDVFFQTAVGDNEERLLSVINLASKRSELVVLCGGLGPTEDDLTKQT
LAKYLGRDLVFDEQANKRLDEFFATRPQFARTANNERQAQLIEGSIPLQNSTGLAVGGVLEVNGVTYVVLPGPPSELKPM
VLDSLVPLLSEGHRQLYSRVLRFFGIGESQLVTVLTDLIDNQTDPTIAPYAKTGEVTLRLSTKANDVTSAKAKLDALEHK
ILAKKTLNGILLEQLLYGYGDDNSMARVVFELLKEKHKTITAAESLTAGLFQSSIADFSGSSAVFNGGFVTYSIEEKSKM
LHIPLEDLQEHGVVSHFTAEKMAEQSRLLTDADFGIGLTGVAGPNSLEGHPAGTVFIGIATREKVHSIRVVLGGRSRSDV
RYIATLYAFNLVRQALLQG

Nucleotide


Download         Length: 1260 bp        

>NTDB_id=762273 OQG81_RS01220 WP_014295450.1 194718..195977(+) (cinA) [Streptococcus macedonicus strain E37]
ATGAAAGCTGAAATCATTGCTGTGGGAACAGAAATTCTAACAGGACAAATCACAAATACAAATGCTCAATTTTTATCGGA
AGAATTTGCCAAGTTAGGAATTGATGTGTTCTTTCAAACAGCTGTTGGTGATAATGAAGAACGTCTTTTATCAGTTATTA
ATTTAGCAAGCAAGCGAAGTGAATTAGTTGTCTTATGTGGAGGGCTTGGTCCGACAGAAGACGATTTAACAAAACAAACG
TTAGCAAAATATTTGGGACGCGATTTAGTCTTTGATGAACAAGCTAACAAGCGTTTGGACGAATTTTTTGCGACACGTCC
GCAGTTTGCTAGAACGGCTAATAACGAACGTCAAGCACAGCTGATTGAAGGGTCAATACCGTTGCAAAATAGCACTGGTT
TGGCTGTTGGTGGCGTGCTAGAAGTAAATGGCGTGACCTATGTTGTTCTCCCTGGACCGCCGAGTGAATTAAAACCAATG
GTATTGGATTCTCTAGTACCTTTATTGTCTGAAGGCCATAGGCAGCTTTATTCACGTGTGTTGCGTTTCTTTGGTATTGG
TGAAAGCCAGTTAGTGACCGTTTTGACAGATTTGATTGATAATCAAACAGACCCAACGATTGCTCCGTATGCGAAAACAG
GTGAGGTGACCCTTCGTTTATCAACCAAGGCAAATGATGTGACGTCAGCAAAAGCGAAATTGGATGCTCTAGAGCATAAA
ATTCTAGCTAAAAAAACATTAAATGGTATTCTTCTTGAACAGTTACTTTATGGCTATGGTGATGATAACAGTATGGCGCG
TGTTGTTTTTGAGTTGTTGAAAGAAAAGCACAAAACCATTACAGCGGCAGAAAGTTTGACTGCAGGGCTATTCCAATCTA
GTATCGCTGATTTTTCAGGGTCATCTGCAGTATTTAATGGCGGATTTGTGACGTATAGTATAGAAGAAAAATCAAAAATG
CTTCACATTCCTCTTGAAGATTTGCAAGAACATGGTGTAGTAAGTCACTTTACAGCTGAAAAAATGGCAGAGCAATCACG
TTTATTGACAGATGCTGATTTTGGTATCGGTTTGACAGGTGTTGCAGGACCAAATAGCTTAGAAGGACATCCAGCAGGAA
CAGTTTTTATTGGTATTGCTACTAGAGAAAAAGTTCATTCTATTCGTGTTGTTCTAGGTGGACGAAGCCGTTCAGACGTC
CGTTATATTGCTACTTTATATGCTTTCAACTTAGTACGTCAAGCTTTATTACAAGGCTAA

Domains

Predicted by InterproScan.

Damage-inducible protein CinA KH domain (CinA_KH)

(178-241)

Competence-damaged protein (CinA)

(263-415)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mutans UA159

71.942

99.523

0.716
  cinA Streptococcus mitis SK321

71.463

99.523

0.711
  cinA Streptococcus mitis NCTC 12261

71.223

99.523

0.709
  cinA Streptococcus pneumoniae Rx1

70.264

99.523

0.699
  cinA Streptococcus pneumoniae TIGR4

70.264

99.523

0.699
  cinA Streptococcus pneumoniae R6

70.264

99.523

0.699
  cinA Streptococcus pneumoniae D39

70.024

99.523

0.697
  cinA Streptococcus suis isolate S10

54.087

99.284

0.537
  cinA Bacillus subtilis subsp. subtilis str. 168

45.498

100

0.458