Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR   Type   Regulator
Locus tag   OQG81_RS00845 Genome accession   NZ_CP113440
Coordinates   122514..123413 (+) Length   299 a.a.
NCBI ID   WP_039670354.1    Uniprot ID   A0A081JJT6
Organism   Streptococcus macedonicus strain E37     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 117514..128413
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OQG81_RS00805 (OQG81_00805) comYF 117608..118075 (+) 468 WP_014293768.1 competence type IV pilus minor pilin ComGF Machinery gene
  OQG81_RS00810 (OQG81_00810) comYG 118047..118352 (+) 306 WP_014293769.1 competence type IV pilus minor pilin ComGG Machinery gene
  OQG81_RS00815 (OQG81_00815) comYH 118434..119390 (+) 957 WP_014293770.1 class I SAM-dependent methyltransferase Machinery gene
  OQG81_RS00820 (OQG81_00820) - 119443..120642 (+) 1200 WP_265643910.1 acetate kinase -
  OQG81_RS00825 (OQG81_00825) - 120804..121004 (+) 201 WP_012961332.1 helix-turn-helix transcriptional regulator -
  OQG81_RS00830 (OQG81_00830) - 121014..121223 (+) 210 WP_014293772.1 hypothetical protein -
  OQG81_RS00835 (OQG81_00835) - 121236..121688 (+) 453 WP_014293773.1 hypothetical protein -
  OQG81_RS00840 (OQG81_00840) - 121700..122335 (+) 636 WP_014293774.1 CPBP family intramembrane glutamic endopeptidase -
  OQG81_RS00845 (OQG81_00845) comR 122514..123413 (+) 900 WP_039670354.1 helix-turn-helix domain-containing protein Regulator
  OQG81_RS00850 (OQG81_00850) purD 123887..125149 (+) 1263 WP_014293776.1 phosphoribosylamine--glycine ligase -
  OQG81_RS00855 (OQG81_00855) - 125139..125588 (+) 450 Protein_121 DUF523 domain-containing protein -
  OQG81_RS00860 (OQG81_00860) purE 125588..126076 (+) 489 WP_061458775.1 5-(carboxyamino)imidazole ribonucleotide mutase -
  OQG81_RS00865 (OQG81_00865) purK 126063..127154 (+) 1092 WP_265643909.1 5-(carboxyamino)imidazole ribonucleotide synthase -
  OQG81_RS00870 (OQG81_00870) - 127174..127397 (+) 224 Protein_124 phosphoribosylaminoimidazole carboxylase -

Sequence

Protein


Download         Length: 299 a.a.        Molecular weight: 34990.12 Da        Isoelectric Point: 4.9629

>NTDB_id=762271 OQG81_RS00845 WP_039670354.1 122514..123413(+) (comR) [Streptococcus macedonicus strain E37]
MEKFGIKVRALREEKGISREEFCGDETELSVRQLARIEKGQSVPTLNKVGYIAKVLDVTIGELVDGKNLELPTRYKELKY
LLLRTPTYGDEKRLQRQTSYFDEIAERYYEVIPEEERLVIDCLQSKIDVHFSDDVNFGEGILNDYFDQVRRKKKFQINDL
ILIDLYFACLASAKSFEGIYSLDLYDELMECLLNQENLSPETSLILNNVLLNNVDLVLRFHRESFIKRIIIKSDTIMASI
HDFQRRPVLSLVEWKYYLQFKKDFLAAQKSYSNAILFANLIGDTYLKSKLVEEWNNDTT

Nucleotide


Download         Length: 900 bp        

>NTDB_id=762271 OQG81_RS00845 WP_039670354.1 122514..123413(+) (comR) [Streptococcus macedonicus strain E37]
TTGGAAAAGTTTGGGATTAAAGTACGTGCATTAAGAGAGGAAAAAGGAATTTCACGTGAGGAATTTTGTGGCGATGAAAC
AGAATTGTCTGTACGGCAATTAGCTAGAATTGAAAAGGGACAATCCGTTCCAACTCTTAATAAAGTGGGATATATTGCAA
AGGTTTTGGACGTAACGATTGGTGAATTAGTTGATGGTAAAAATCTAGAGCTTCCTACTAGATACAAGGAGTTAAAGTAT
TTATTATTGCGAACACCGACTTATGGAGATGAGAAACGTCTTCAGAGACAAACTTCCTATTTTGACGAGATTGCAGAAAG
ATATTACGAAGTTATACCTGAAGAGGAACGTTTGGTTATTGATTGTTTACAATCAAAGATTGATGTTCATTTCAGTGATG
ATGTTAATTTTGGTGAGGGAATTTTAAATGACTATTTTGACCAGGTTAGACGAAAGAAAAAATTTCAAATCAATGATTTG
ATTTTAATAGATTTATATTTTGCTTGCCTTGCTTCTGCTAAATCGTTTGAGGGAATCTATAGCTTAGATTTATATGATGA
ATTAATGGAGTGTTTGCTGAATCAAGAAAATCTTTCGCCAGAAACTTCTTTGATTTTAAATAATGTTTTATTAAATAATG
TAGATTTGGTTTTACGATTCCATAGAGAATCATTTATAAAACGAATAATTATAAAAAGCGACACTATCATGGCAAGTATT
CATGATTTTCAAAGACGTCCAGTTTTAAGTTTAGTTGAGTGGAAATATTATTTACAATTTAAAAAAGATTTTTTAGCGGC
ACAAAAATCTTACTCCAATGCAATTTTATTTGCTAATTTAATTGGAGATACTTATTTGAAAAGTAAATTAGTAGAAGAAT
GGAATAATGATACAACATGA

Domains

Predicted by InterproScan.

Helix-turn-helix (HTH_3)

(8-63)

ComR tetratricopeptide (ComR_TPR)

(72-294)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A081JJT6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR Streptococcus infantarius subsp. infantarius ATCC BAA-102

72.125

95.987

0.692
  comR Streptococcus mutans UA159

53.512

100

0.535
  comR Streptococcus pyogenes MGAS8232

49

100

0.492
  comR Streptococcus pyogenes MGAS315

47.987

99.666

0.478
  comR Streptococcus suis P1/7

39.933

99.666

0.398
  comR Streptococcus suis 05ZYH33

40.067

99.331

0.398
  comR Streptococcus suis D9

38.591

99.666

0.385