Detailed information NTG0762267

Bioinformatically predicted

Overview

• Name: comYF
• Type: Machinery gene
• Locus tag: OQG81_RS00805
• Genome accession: NZ_CP113440
• Coordinates: 117608..118075 (+)
• Length: 155 a.a.
• NCBI ID: WP_014293768.1
• Uniprot ID: A0A380K3J6
• Organism: Streptococcus macedonicus strain E37
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 112608..123075

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
OQG81_RS00775 (OQG81_00775)	-	114352..114681 (+)	330	WP_014293762.1	DUF1033 family protein	-
OQG81_RS00780 (OQG81_00780)	comYA	114791..115732 (+)	942	WP_014293763.1	competence type IV pilus ATPase ComGA	Machinery gene
OQG81_RS00785 (OQG81_00785)	comYB	115614..116699 (+)	1086	WP_014293764.1	competence type IV pilus assembly protein ComGB	Machinery gene
OQG81_RS00790 (OQG81_00790)	comYC	116699..116992 (+)	294	WP_039670352.1	competence type IV pilus major pilin ComGC	Machinery gene
OQG81_RS00795 (OQG81_00795)	comYD	116976..117407 (+)	432	WP_014293766.1	competence type IV pilus minor pilin ComGD	Machinery gene
OQG81_RS00800 (OQG81_00800)	comGE	117361..117654 (+)	294	WP_044562943.1	competence type IV pilus minor pilin ComGE	-
OQG81_RS00805 (OQG81_00805)	comYF	117608..118075 (+)	468	WP_014293768.1	competence type IV pilus minor pilin ComGF	Machinery gene
OQG81_RS00810 (OQG81_00810)	comYG	118047..118352 (+)	306	WP_014293769.1	competence type IV pilus minor pilin ComGG	Machinery gene
OQG81_RS00815 (OQG81_00815)	comYH	118434..119390 (+)	957	WP_014293770.1	class I SAM-dependent methyltransferase	Machinery gene
OQG81_RS00820 (OQG81_00820)	-	119443..120642 (+)	1200	WP_265643910.1	acetate kinase	-
OQG81_RS00825 (OQG81_00825)	-	120804..121004 (+)	201	WP_012961332.1	helix-turn-helix transcriptional regulator	-
OQG81_RS00830 (OQG81_00830)	-	121014..121223 (+)	210	WP_014293772.1	hypothetical protein	-
OQG81_RS00835 (OQG81_00835)	-	121236..121688 (+)	453	WP_014293773.1	hypothetical protein	-
OQG81_RS00840 (OQG81_00840)	-	121700..122335 (+)	636	WP_014293774.1	CPBP family intramembrane glutamic endopeptidase	-

Sequence

Protein

• Length: 155 a.a.
• Molecular weight: 17564.08 Da
• Isoelectric Point: 9.2496

>NTDB_id=762267 OQG81_RS00805 WP_014293768.1 117608..118075(+) (comYF) [Streptococcus macedonicus strain E37]
MFMRGKRKYYTLKKTSLEAFSLIECLVSLLVISGAILVYNGLTQYISANVHYLSENQEENWLLFSQQLRAELANCQLDKV
ENNKLYVTKSSQKLAFGQSKADDFRKTNASGQGYQPMIFGVKSSAISRDGQKVTMTLNLENGLERTFVYTFETAS

Nucleotide

• Length: 468 bp

>NTDB_id=762267 OQG81_RS00805 WP_014293768.1 117608..118075(+) (comYF) [Streptococcus macedonicus strain E37]
ATGTTTATGAGGGGAAAACGGAAATATTACACGTTAAAAAAGACTAGTTTAGAGGCATTCAGCCTCATAGAATGTTTGGT
TTCTTTATTAGTAATTTCGGGTGCTATTCTTGTTTACAATGGCTTAACGCAATATATTTCTGCAAATGTGCATTATTTGT
CGGAAAATCAAGAGGAAAACTGGCTTTTGTTTTCACAACAGCTGCGTGCGGAGCTTGCCAATTGTCAATTAGATAAGGTT
GAAAATAACAAACTATATGTGACGAAGTCCAGTCAAAAGTTGGCATTTGGACAGTCAAAGGCTGATGATTTTCGTAAAAC
AAACGCATCTGGTCAAGGCTATCAGCCAATGATATTTGGAGTAAAATCTTCTGCTATTTCTAGAGATGGTCAGAAGGTGA
CAATGACATTGAATTTAGAGAATGGTTTGGAGAGGACATTTGTTTACACTTTTGAAACGGCAAGTTAA

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (49-144)

3D structure

• AlphaFold DB: A0A380K3J6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYF	Streptococcus mutans UA140	56.835	89.677	0.51
comYF	Streptococcus mutans UA159	56.115	89.677	0.503
comGF/cglF	Streptococcus pneumoniae Rx1	44.286	90.323	0.4
comGF/cglF	Streptococcus pneumoniae D39	44.286	90.323	0.4
comGF/cglF	Streptococcus pneumoniae R6	44.286	90.323	0.4
comGF/cglF	Streptococcus pneumoniae TIGR4	44.286	90.323	0.4
comGF/cglF	Streptococcus mitis NCTC 12261	42.958	91.613	0.394
comGF/cglF	Streptococcus mitis SK321	42.254	91.613	0.387
comGF	Lactococcus lactis subsp. cremoris KW2	43.478	89.032	0.387