Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   QL281_RS11845 Genome accession   NZ_CP125292
Coordinates   2205223..2206425 (-) Length   400 a.a.
NCBI ID   WP_017695783.1    Uniprot ID   -
Organism   Bacillus subtilis strain SRCM117797     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2200223..2211425
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QL281_RS11820 (QL281_11820) rocE 2200457..2201860 (-) 1404 WP_017695780.1 amino acid permease -
  QL281_RS11825 (QL281_11825) rocD 2202083..2203288 (-) 1206 WP_017695781.1 ornithine aminotransferase -
  QL281_RS11830 (QL281_11830) rocR 2203526..2204911 (+) 1386 WP_283009848.1 arginine utilization regulatory protein RocR -
  QL281_RS11835 (QL281_11835) - 2204893..2205045 (-) 153 Protein_2335 ATP-binding protein -
  QL281_RS11840 (QL281_11840) - 2205073..2205203 (-) 131 Protein_2336 hypothetical protein -
  QL281_RS11845 (QL281_11845) htrA 2205223..2206425 (-) 1203 WP_017695783.1 serine protease HtrC Regulator
  QL281_RS11850 (QL281_11850) vicX 2206507..2207301 (-) 795 WP_003226939.1 MBL fold metallo-hydrolase Regulator
  QL281_RS11855 (QL281_11855) walI 2207323..2208165 (-) 843 WP_017695784.1 WalRK two-component regulatory system regulator WalI -
  QL281_RS11860 (QL281_11860) walH 2208152..2209519 (-) 1368 WP_041054960.1 WalRK two-component regulatory system regulator WalH -
  QL281_RS11865 (QL281_11865) walK 2209509..2211344 (-) 1836 WP_009968432.1 cell wall metabolism sensor histidine kinase WalK -

Sequence

Protein


Download         Length: 400 a.a.        Molecular weight: 42885.74 Da        Isoelectric Point: 5.5235

>NTDB_id=762264 QL281_RS11845 WP_017695783.1 2205223..2206425(-) (htrA) [Bacillus subtilis strain SRCM117797]
MVNYEREEEHTTPEQPKRSKKGYFLSSLIGVIVGAVLMAFIMPYLSNEGLDTGVLDQQQNNNGRESIRTVNVSVNNAATK
IVSNVSPAVVGVVNIQKSDIWGESGEAGSGSGVIYKKNDHSAYVVTNHHVIEGASQIEISLKDGSRVPADLVGSDQLMDL
AVLRVKSDKIKAVADFGNSDKVKSGEPVIAIGNPLGLEFAGSVTQGVISGTERAIPVDSNGDGQPDWNAEVLQTDAAINP
GNSGGALLNMDGKVIGINSMKIAESAVEGIGLSIPSKLVIPVIEDLERYGKVKRPFLGIEMKSLSDIASYHWYETLKLPK
NVTNGVVVMGVDAFSPAAKAGLKELDVITEFDGYKVNDIVDLRKRLYQKKVGDWVKVKFYRGGKEKSVDIKLSSADQLGS

Nucleotide


Download         Length: 1203 bp        

>NTDB_id=762264 QL281_RS11845 WP_017695783.1 2205223..2206425(-) (htrA) [Bacillus subtilis strain SRCM117797]
ATGGTGAATTATGAACGTGAGGAAGAACATACTACTCCTGAACAGCCAAAGAGAAGCAAAAAAGGATATTTTCTTTCGAG
TCTGATTGGCGTGATTGTCGGTGCCGTATTAATGGCGTTTATCATGCCGTACCTTTCAAATGAAGGGCTGGATACAGGCG
TCTTAGATCAGCAGCAAAACAACAACGGCCGGGAATCAATCAGGACGGTGAATGTCAGTGTCAACAATGCCGCCACCAAG
ATTGTCAGCAATGTGTCGCCCGCCGTTGTCGGTGTTGTGAACATCCAAAAATCAGATATTTGGGGAGAGAGCGGCGAGGC
TGGGAGCGGCTCAGGCGTCATCTATAAGAAAAATGACCATTCCGCTTATGTCGTGACCAACCATCATGTCATCGAAGGCG
CTTCCCAAATTGAAATCAGCTTGAAAGACGGATCGCGTGTACCAGCTGATCTTGTCGGCAGCGACCAGCTGATGGACCTT
GCCGTTTTACGGGTGAAAAGCGATAAAATTAAAGCAGTCGCCGATTTCGGAAATTCAGATAAAGTGAAGTCTGGGGAGCC
GGTTATTGCGATCGGGAACCCGTTAGGCCTTGAGTTTGCTGGCTCTGTCACACAAGGCGTCATCTCGGGTACGGAGAGGG
CGATCCCAGTAGATTCAAACGGTGATGGACAGCCTGACTGGAACGCAGAAGTCCTGCAAACAGATGCGGCCATTAACCCT
GGGAACAGCGGCGGCGCTTTGTTAAATATGGATGGGAAGGTCATTGGCATCAATTCAATGAAAATTGCCGAGTCAGCGGT
TGAAGGGATTGGCCTGTCCATTCCGTCTAAGCTCGTGATCCCTGTGATAGAGGATTTAGAGAGATACGGAAAGGTCAAAC
GCCCGTTCCTTGGCATTGAGATGAAATCCCTAAGCGACATCGCAAGCTATCATTGGTATGAAACATTAAAGCTTCCTAAG
AACGTCACCAATGGAGTGGTTGTGATGGGTGTAGACGCCTTTTCACCTGCCGCAAAAGCGGGGCTGAAGGAACTGGATGT
CATCACGGAATTTGACGGATACAAAGTAAATGATATTGTTGACCTGCGAAAACGGCTTTATCAGAAAAAAGTCGGTGACT
GGGTGAAGGTGAAGTTTTATCGCGGCGGAAAAGAAAAATCTGTTGATATCAAGCTGTCCTCCGCAGACCAATTAGGCAGT
TAA

Domains

Predicted by InterProScan.

PDZ domain (PDZ_2)

(295-392)

Trypsin-like peptidase domain (Trypsin_2)

(110-257)

Peptidase family M50 (Peptidase_M50)

(218-395)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mutans UA159

43.434

99

0.43
  htrA Streptococcus mitis NCTC 12261

43.523

96.5

0.42
  htrA Streptococcus gordonii str. Challis substr. CH1

41.397

100

0.415
  htrA Streptococcus pneumoniae TIGR4

45.758

82.5

0.378
  htrA Streptococcus pneumoniae D39

45.758

82.5

0.378
  htrA Streptococcus pneumoniae Rx1

45.758

82.5

0.378
  htrA Streptococcus pneumoniae R6

45.758

82.5

0.378