Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   OS912_RS04790 Genome accession   NZ_CP113266
Coordinates   945693..946949 (-) Length   418 a.a.
NCBI ID   WP_050136975.1    Uniprot ID   A0A0T9AM81
Organism   Streptococcus pneumoniae strain BC1     
Function   facilitate localization of RecA (predicted from homology)   
Homologous recombination

Genomic Context

Location: 940693..951949
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OS912_RS04770 (OS912_04775) - 940925..941098 (-) 174 WP_001056002.1 helix-turn-helix domain-containing protein -
  OS912_RS04775 (OS912_04780) lytA 941463..942419 (-) 957 WP_000405234.1 N-acetylmuramoyl-L-alanine amidase LytA -
  OS912_RS04780 (OS912_04785) - 942795..944165 (-) 1371 WP_268233029.1 MATE family efflux transporter -
  OS912_RS04785 (OS912_04790) recA 944472..945638 (-) 1167 WP_001085463.1 recombinase RecA Machinery gene
  OS912_RS04790 (OS912_04795) cinA 945693..946949 (-) 1257 WP_050136975.1 competence/damage-inducible protein A Machinery gene
  OS912_RS04795 (OS912_04800) brpA 947034..948050 (-) 1017 WP_000239283.1 biofilm formation/cell division transcriptional regulator BrpA -
  OS912_RS04800 (OS912_04805) - 948058..948576 (-) 519 WP_138024452.1 GNAT family N-acetyltransferase -
  OS912_RS04805 (OS912_04810) tsaE 948566..949009 (-) 444 WP_000288232.1 tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE -
  OS912_RS04810 (OS912_04815) comM 949095..949715 (-) 621 WP_000839908.1 hypothetical protein Regulator
  OS912_RS04815 (OS912_04820) - 950098..950961 (-) 864 WP_050214053.1 helix-turn-helix domain-containing protein -
  OS912_RS04820 (OS912_04825) - 951149..951318 (+) 170 Protein_945 PhrA family quorum-sensing system peptide -
  OS912_RS04825 (OS912_04830) - 951633..951929 (+) 297 WP_000911560.1 lactococcin 972 family bacteriocin -

Sequence

Protein


Download         Length: 418 a.a.        Molecular weight: 45032.42 Da        Isoelectric Point: 4.6461

>NTDB_id=761404 OS912_RS04790 WP_050136975.1 945693..946949(-) (cinA) [Streptococcus pneumoniae strain BC1]
MKAEIIAVGTEILTGQIVNTNAQFLSEKLAEIGVDVYFQTAVGDNEVRLLSLLEIASQRSSLVILTGGLGPTEDDLTKQT
LAKFLGKALVFNPQAQEKLDIFFALRPDYARTPNNERQAQIVEGAIPLPNETGLAVGGKLEVDGVTYVVLPGPPSELKPM
VLNQLLPKLMTGSKLYSRVLRFFGIGESQLVTILADLIDNQIDPTLAPYAKTGEVTLRLSTKASSQEEANQALDILENQI
LDCQTFEGISLRDFCYGYGEETSLASIVVEELKRQGKTIAAAESLTAGLFQATVANFSGASSIFKGGFVTYSLEEKSRML
DIPAKNLEEHGVVSEFTAQKMAEQARSKTQSDFGISLTGVAGPDSLEGHPVGTVFIGLAQDQGTEVIKVNIGGRSRADVR
HIAVMHAFNLVRKALLSD

Nucleotide


Download         Length: 1257 bp        

>NTDB_id=761404 OS912_RS04790 WP_050136975.1 945693..946949(-) (cinA) [Streptococcus pneumoniae strain BC1]
ATGAAAGCAGAAATCATTGCTGTTGGAACAGAGATTTTGACAGGGCAGATTGTCAACACCAATGCCCAGTTTTTGTCGGA
AAAACTAGCTGAGATTGGGGTAGATGTATATTTTCAGACGGCTGTAGGAGACAATGAAGTTCGTCTCTTGTCTTTGCTTG
AGATTGCCAGTCAACGTAGTAGTCTGGTGATTTTGACAGGCGGTTTGGGGCCAACTGAGGACGACCTAACCAAACAAACC
CTAGCTAAATTTTTAGGGAAAGCATTAGTCTTTAATCCTCAGGCTCAGGAGAAGTTGGATATCTTTTTTGCCCTGCGACC
AGACTATGCCCGAACACCGAATAACGAAAGACAAGCTCAAATTGTAGAAGGAGCGATTCCACTGCCAAACGAAACAGGAC
TGGCTGTTGGAGGAAAATTAGAAGTAGACGGAGTGACCTATGTCGTCCTTCCAGGTCCGCCAAGTGAATTGAAACCCATG
GTCTTAAACCAACTTCTACCCAAGTTGATGACAGGGAGCAAGCTGTATTCCCGAGTTCTTCGTTTCTTTGGGATTGGCGA
GAGCCAGCTGGTTACGATTTTGGCTGATTTAATTGATAATCAGATCGATCCTACCTTGGCCCCTTATGCTAAGACAGGAG
AAGTCACTCTACGTCTGTCAACAAAGGCTAGCAGTCAAGAAGAGGCGAATCAAGCGCTGGATATCTTGGAAAATCAAATC
TTGGACTGCCAGACTTTCGAAGGAATTTCTTTACGAGACTTTTGCTATGGTTATGGGGAAGAAACTAGTTTAGCCAGCAT
TGTGGTAGAAGAACTGAAAAGGCAAGGGAAAACCATCGCGGCTGCAGAGAGTTTAACGGCAGGTCTTTTCCAAGCTACCG
TGGCGAATTTTTCTGGAGCTTCAAGTATATTTAAGGGTGGTTTTGTGACCTATAGCTTGGAGGAAAAATCAAGGATGTTG
GATATTCCTGCCAAGAATTTGGAAGAACATGGTGTGGTGTCTGAATTTACAGCTCAGAAGATGGCTGAGCAGGCACGAAG
CAAGACCCAGTCTGATTTTGGAATTAGTTTGACTGGAGTGGCAGGACCAGATAGCCTAGAAGGACACCCAGTTGGGACAG
TCTTCATAGGCTTGGCGCAAGATCAAGGAACTGAGGTTATCAAGGTTAATATTGGAGGCAGAAGCCGAGCAGATGTACGT
CACATTGCGGTTATGCATGCCTTTAACCTAGTTCGCAAGGCTTTATTAAGTGACTAA

Domains

Predicted by InterproScan.

Damage-inducible protein CinA KH domain (CinA_KH)

(177-240)

Competence-damaged protein (CinA)

(262-414)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0T9AM81

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus pneumoniae TIGR4

99.282

100

0.993
  cinA Streptococcus pneumoniae Rx1

99.043

100

0.99
  cinA Streptococcus pneumoniae R6

99.043

100

0.99
  cinA Streptococcus pneumoniae D39

98.804

100

0.988
  cinA Streptococcus mitis SK321

93.78

100

0.938
  cinA Streptococcus mitis NCTC 12261

93.541

100

0.935
  cinA Streptococcus mutans UA159

71.053

100

0.711
  cinA Streptococcus suis isolate S10

54.808

99.522

0.545
  cinA Bacillus subtilis subsp. subtilis str. 168

45.933

100

0.459