Detailed information    

insolico Bioinformatically predicted

Overview

Name   comM   Type   Regulator
Locus tag   OS912_RS04810 Genome accession   NZ_CP113266
Coordinates   949095..949715 (-) Length   206 a.a.
NCBI ID   WP_000839908.1    Uniprot ID   A0A0B7M636
Organism   Streptococcus pneumoniae strain BC1     
Function   fratricide immunity (predicted from homology)   
Competence regulation

Genomic Context

Location: 944095..954715
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OS912_RS04785 (OS912_04790) recA 944472..945638 (-) 1167 WP_001085463.1 recombinase RecA Machinery gene
  OS912_RS04790 (OS912_04795) cinA 945693..946949 (-) 1257 WP_050136975.1 competence/damage-inducible protein A Machinery gene
  OS912_RS04795 (OS912_04800) brpA 947034..948050 (-) 1017 WP_000239283.1 biofilm formation/cell division transcriptional regulator BrpA -
  OS912_RS04800 (OS912_04805) - 948058..948576 (-) 519 WP_138024452.1 GNAT family N-acetyltransferase -
  OS912_RS04805 (OS912_04810) tsaE 948566..949009 (-) 444 WP_000288232.1 tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE -
  OS912_RS04810 (OS912_04815) comM 949095..949715 (-) 621 WP_000839908.1 hypothetical protein Regulator
  OS912_RS04815 (OS912_04820) - 950098..950961 (-) 864 WP_050214053.1 helix-turn-helix domain-containing protein -
  OS912_RS04820 (OS912_04825) - 951149..951318 (+) 170 Protein_945 PhrA family quorum-sensing system peptide -
  OS912_RS04825 (OS912_04830) - 951633..951929 (+) 297 WP_000911560.1 lactococcin 972 family bacteriocin -
  OS912_RS04830 (OS912_04835) - 952032..954047 (+) 2016 WP_000732371.1 DUF1430 domain-containing protein -
  OS912_RS04835 (OS912_04840) - 954049..954681 (+) 633 WP_000571425.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 206 a.a.        Molecular weight: 23552.72 Da        Isoelectric Point: 10.1254

>NTDB_id=761405 OS912_RS04810 WP_000839908.1 949095..949715(-) (comM) [Streptococcus pneumoniae strain BC1]
MKSMRILFLLALIQISLSSCFLWKECILSFKQSTAFFIGSMVFVSGICAGVNYLYTRKQEVHSVLASKKSVKLFYSMLLL
INLLGAVLVLSDNLFIKNTLQQELVDFLLPSFFFLFGLDLLIFLPLKKYVRDFLAMLDRKKTVLVTILATLLFLRNPMTI
VSLLIYIGLGLFFAAYLVPNSVKKEVSFYGHIFRDLVLVIVTLIFF

Nucleotide


Download         Length: 621 bp        

>NTDB_id=761405 OS912_RS04810 WP_000839908.1 949095..949715(-) (comM) [Streptococcus pneumoniae strain BC1]
ATGAAATCAATGAGAATCTTATTTTTGTTAGCTTTAATTCAAATCAGTTTGAGTAGCTGTTTCCTATGGAAGGAATGCAT
CTTGTCCTTTAAACAAAGTACAGCTTTTTTCATCGGAAGCATGGTTTTCGTTTCAGGAATCTGTGCTGGAGTAAATTATC
TTTATACCCGTAAGCAAGAAGTCCATAGTGTCCTAGCCAGTAAGAAGTCGGTGAAGCTTTTTTACAGTATGTTACTCTTA
ATTAATTTGTTAGGAGCTGTTCTTGTTTTGTCAGATAACTTGTTCATCAAAAATACGCTGCAGCAAGAATTAGTTGACTT
TTTATTGCCATCCTTCTTTTTCCTATTTGGGCTAGATTTGCTGATTTTTTTACCCTTGAAAAAATACGTGCGCGATTTTC
TTGCTATGCTAGACAGAAAAAAGACAGTGTTGGTGACTATTTTAGCAACACTTCTTTTCTTAAGAAATCCAATGACCATT
GTCTCACTTCTGATTTATATTGGACTGGGCTTGTTTTTTGCAGCCTATCTTGTCCCAAATTCGGTTAAGAAGGAAGTTTC
CTTTTATGGTCATATTTTCCGAGATCTTGTATTGGTCATTGTTACGCTCATTTTCTTTTAG

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0B7M636

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comM Streptococcus pneumoniae D39

100

100

1
  comM Streptococcus pneumoniae R6

100

100

1
  comM Streptococcus pneumoniae TIGR4

100

100

1
  comM Streptococcus mitis NCTC 12261

38.974

94.66

0.369
  comM Streptococcus mitis SK321

38.974

94.66

0.369