Detailed information NTG0758592

Bioinformatically predicted

Overview

• Name: comEC
• Type: Machinery gene
• Locus tag: ORF34_RS13870
• Genome accession: NZ_CP112873
• Coordinates: 2639347..2641677 (-)
• Length: 776 a.a.
• NCBI ID: WP_009967776.1
• Uniprot ID: A0AAE2SL11
• Organism: Bacillus subtilis strain O4
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2634347..2646677

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ORF34_RS13835 (ORF34_13835)	yqxA	2634686..2635024 (-)	339	WP_004399162.1	YqxA family protein	-
ORF34_RS13840 (ORF34_13840)	spoIIP	2635041..2636246 (-)	1206	WP_003229993.1	spore autolysin SpoIIP	-
ORF34_RS13845 (ORF34_13845)	gpr	2636309..2637415 (-)	1107	WP_003229991.1	GPR endopeptidase	-
ORF34_RS13850 (ORF34_13850)	rpsT	2637619..2637885 (+)	267	WP_003229989.1	30S ribosomal protein S20	-
ORF34_RS13855 (ORF34_13855)	holA	2637900..2638943 (-)	1044	WP_003229987.1	DNA polymerase III subunit delta	-
ORF34_RS13860 (ORF34_13860)	-	2638983..2639132 (-)	150	WP_003229985.1	hypothetical protein	-
ORF34_RS13865 (ORF34_13865)	yqzM	2639173..2639307 (+)	135	WP_003229983.1	YqzM family protein	-
ORF34_RS13870 (ORF34_13870)	comEC	2639347..2641677 (-)	2331	WP_009967776.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
ORF34_RS13875 (ORF34_13875)	comEB	2641681..2642250 (-)	570	WP_003229978.1	ComE operon protein 2	-
ORF34_RS13880 (ORF34_13880)	comEA	2642317..2642934 (-)	618	WP_004398514.1	competence protein ComEA	Machinery gene
ORF34_RS13885 (ORF34_13885)	comER	2643018..2643839 (+)	822	WP_004398597.1	late competence protein ComER	-
ORF34_RS13890 (ORF34_13890)	yqeM	2643905..2644648 (-)	744	WP_003229973.1	class I SAM-dependent DNA methyltransferase	-
ORF34_RS13895 (ORF34_13895)	rsfS	2644645..2645001 (-)	357	WP_003229971.1	ribosome silencing factor	-
ORF34_RS13900 (ORF34_13900)	yqeK	2645019..2645579 (-)	561	WP_004399059.1	bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK	-
ORF34_RS13905 (ORF34_13905)	nadD	2645569..2646138 (-)	570	WP_004398676.1	nicotinate-nucleotide adenylyltransferase	-
ORF34_RS13910 (ORF34_13910)	yhbY	2646150..2646440 (-)	291	WP_003226133.1	ribosome assembly RNA-binding protein YhbY	-

Sequence

Protein

• Length: 776 a.a.
• Molecular weight: 86701.36 Da
• Isoelectric Point: 7.3497

>NTDB_id=758592 ORF34_RS13870 WP_009967776.1 2639347..2641677(-) (comEC) [Bacillus subtilis strain O4]
MRNSRLLLPMAAASATAGITAAAYFPAIFLFILFLLIILIKTRHAFLIIVCFFSFILFFVLYAVTDSQNVSSYRQGTYQF
KAVIDTIPKIDGDRMSMMVETPDKEKWAAAYRIQSAGEKEQLLYIEPGMSCELTGTLEEPNHATVPGAFDYNEYLYRQHI
HWNYSVTSIQNCSEPENFKYKVLSLRKHIISFTNSLLPPDSTGIVQALTVGDRFYVEDEVLTAYQKLGVVHLLAISGLHV
GILTAGLFYIMIRLGITREKASILLLLFLPLYVMLTGAAPSVLRAALMSGVYLAGSLVKWRVRSATAICLSYIVLLLFNP
YHLFEAGFQLSFAVSFSLILSSSIFQQVKTSLGQLTIVSLIAQLGSLPILLYHFHQFSIISVPMNMLMVPFYTFCILPGA
VAGVLLLSLSASFGRLFFSWFDLLISWINRLITNIADVDVFTIMIAHPAPVLLFLFTVTIILLLMAIEKRSLSQLMVTGG
ICCTVMFLLFIYPCLSSEGEVDMIDIGQGDSMFVGAPHQRGRVLIDTGGTLSYSSEPWREKQHPFSLGEKVLIPFLTAKG
IKQLDALILTHADQDHIGEAEILLKHHKVKRLVIPKGFVSEPKDEKVLQAAREEGVAIEEVKRGDVLQIKDLQFHVLSPE
APDPASKNNSSLVLWMETGGMSWILTGDLEKEGEQEVMNVFPNIKADVLKVGHHGSKGSTGEEFIQQLQPKTAIISAGKN
NRYHHPHQKVLQLLQRHSIRVLRTDQNGTIQYRYKNRVGTFSVYPPYDTSDITETN

Nucleotide

• Length: 2331 bp

>NTDB_id=758592 ORF34_RS13870 WP_009967776.1 2639347..2641677(-) (comEC) [Bacillus subtilis strain O4]
ATGCGTAATTCGCGCTTATTATTGCCTATGGCGGCAGCTTCGGCAACGGCTGGAATTACTGCCGCCGCTTATTTCCCCGC
TATTTTTCTTTTCATCCTCTTTCTCCTCATCATTTTAATCAAAACGAGGCACGCTTTTCTTATTATTGTTTGTTTCTTCT
CTTTTATATTGTTTTTTGTACTGTATGCAGTCACAGATTCTCAGAATGTCTCTTCCTATCGGCAGGGAACCTATCAATTC
AAGGCAGTGATTGACACTATTCCCAAAATTGACGGCGACCGTATGTCTATGATGGTTGAGACACCTGATAAGGAAAAATG
GGCTGCTGCGTATCGCATTCAGTCTGCTGGTGAAAAAGAACAGCTGTTATACATAGAACCAGGAATGTCATGTGAGTTGA
CTGGTACATTGGAAGAACCGAATCACGCAACTGTGCCGGGTGCATTTGATTATAACGAGTATCTTTATCGGCAGCATATT
CATTGGAACTACTCTGTCACGTCTATCCAAAACTGCAGCGAACCTGAAAATTTCAAGTACAAGGTGCTCAGCTTGAGAAA
ACATATCATATCATTCACAAACAGCCTTCTGCCTCCTGATTCGACAGGGATTGTACAGGCACTTACAGTTGGTGACAGAT
TTTACGTGGAGGATGAAGTGCTTACCGCGTATCAAAAGCTTGGTGTTGTCCATCTCTTGGCAATATCAGGACTCCACGTG
GGGATTTTGACAGCAGGTTTGTTTTATATCATGATCCGCCTTGGTATAACTAGAGAAAAGGCGTCAATTCTGTTGCTGTT
ATTTCTGCCGCTCTATGTGATGTTGACCGGCGCTGCTCCTTCAGTGCTACGCGCCGCTCTCATGTCGGGTGTTTACTTAG
CTGGAAGTCTTGTCAAATGGCGTGTCCGCTCTGCAACTGCAATTTGCCTTTCGTACATCGTCCTTCTGCTCTTCAATCCT
TATCATCTCTTTGAAGCCGGTTTTCAGCTATCGTTCGCCGTCAGTTTTTCTTTAATTCTATCCTCTTCTATTTTTCAGCA
GGTTAAAACCTCCTTGGGGCAGCTGACAATTGTATCACTCATCGCTCAGCTGGGCTCGCTTCCGATTCTCCTATATCATT
TTCATCAGTTTTCTATCATCAGCGTACCGATGAATATGTTGATGGTACCATTTTATACCTTCTGTATTTTGCCGGGAGCT
GTAGCAGGTGTTCTTCTATTAAGTCTTTCCGCTTCGTTTGGGAGATTGTTTTTCAGCTGGTTTGATTTATTGATAAGCTG
GATCAATAGGTTAATCACAAACATTGCAGATGTTGATGTGTTCACGATTATGATCGCACATCCTGCACCTGTTTTGCTTT
TTTTATTCACAGTCACGATCATCCTATTGCTTATGGCGATTGAAAAACGCTCCTTGTCGCAGTTGATGGTAACCGGAGGC
ATTTGCTGCACGGTGATGTTTCTGCTCTTTATATATCCGTGTCTTAGTTCCGAAGGAGAAGTGGATATGATAGATATTGG
ACAGGGTGACAGCATGTTTGTAGGTGCTCCGCATCAGCGGGGTCGTGTCTTAATTGATACCGGCGGCACTTTGTCTTACT
CGTCAGAGCCTTGGCGCGAAAAACAGCATCCGTTTTCACTGGGGGAAAAGGTGCTGATTCCGTTTTTAACTGCTAAGGGA
ATCAAGCAGCTTGACGCTTTAATTCTGACGCACGCTGACCAAGATCATATCGGAGAGGCGGAGATTCTGCTGAAGCATCA
TAAAGTAAAGCGCCTCGTGATTCCGAAAGGGTTCGTTTCTGAACCTAAAGATGAGAAAGTGCTGCAGGCAGCCAGGGAAG
AGGGAGTGGCAATTGAAGAGGTGAAGCGAGGCGATGTGTTGCAAATAAAGGATTTGCAGTTCCATGTACTGTCACCGGAA
GCACCTGATCCGGCAAGCAAAAATAATTCATCTCTCGTTCTGTGGATGGAGACGGGCGGTATGAGCTGGATCTTGACGGG
TGATCTGGAGAAAGAAGGGGAACAAGAGGTGATGAACGTGTTTCCGAATATAAAAGCAGATGTGTTAAAGGTGGGGCACC
ATGGGAGCAAAGGCTCTACCGGTGAAGAATTCATCCAACAGCTTCAGCCGAAAACGGCCATTATCTCAGCCGGGAAAAAC
AATCGGTACCATCATCCTCATCAAAAAGTTCTGCAACTATTACAGAGACATTCTATCCGCGTGCTGCGAACAGATCAAAA
CGGAACGATCCAATATAGATACAAAAACAGAGTTGGAACCTTTTCTGTCTATCCTCCATATGATACATCAGATATAACAG
AGACGAACTAA

Domains

Predicted by InterproScan.

• Competence protein (Competence) (208-469)

• Domain of unknown function (DUF4131) (DUF4131) (20-170)

• Metallo-beta-lactamase superfamily (Lactamase_B) (507-718)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC	Bacillus subtilis subsp. subtilis str. 168	100	100	1