Detailed information NTG0746443

Bioinformatically predicted

Overview

• Name: comGC
• Type: Machinery gene
• Locus tag: QAO25_RS02940
• Genome accession: NZ_CP123095
• Coordinates: 554335..554646 (+)
• Length: 103 a.a.
• NCBI ID: WP_000472256.1
• Uniprot ID: A0A0H2XGS7
• Organism: Staphylococcus aureus strain MRSA-COL
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 549335..559646

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QAO25_RS02910 (QAO25_02910)	-	550118..550321 (+)	204	WP_000087561.1	YqgQ family protein	-
QAO25_RS02915 (QAO25_02915)	-	550318..551304 (+)	987	WP_000161314.1	ROK family glucokinase	-
QAO25_RS02920 (QAO25_02920)	-	551304..551633 (+)	330	WP_001018871.1	MTH1187 family thiamine-binding protein	-
QAO25_RS02925 (QAO25_02925)	-	551630..552253 (+)	624	WP_001223008.1	MBL fold metallo-hydrolase	-
QAO25_RS02930 (QAO25_02930)	comGA	552305..553279 (+)	975	WP_000697228.1	competence type IV pilus ATPase ComGA	Machinery gene
QAO25_RS02935 (QAO25_02935)	comGB	553251..554321 (+)	1071	WP_000775708.1	competence type IV pilus assembly protein ComGB	Machinery gene
QAO25_RS02940 (QAO25_02940)	comGC	554335..554646 (+)	312	WP_000472256.1	competence type IV pilus major pilin ComGC	Machinery gene
QAO25_RS02945 (QAO25_02945)	comGD	554624..555070 (+)	447	WP_001790850.1	competence type IV pilus minor pilin ComGD	Machinery gene
QAO25_RS02950 (QAO25_02950)	comGE	555057..555356 (+)	300	WP_000844413.1	hypothetical protein	Machinery gene
QAO25_RS02955 (QAO25_02955)	comGF	555274..555771 (+)	498	WP_001789864.1	competence type IV pilus minor pilin ComGF	Machinery gene
QAO25_RS02960 (QAO25_02960)	-	555868..556014 (+)	147	WP_001789879.1	hypothetical protein	-
QAO25_RS02965 (QAO25_02965)	-	556004..556528 (+)	525	WP_001015117.1	shikimate kinase	-
QAO25_RS02970 (QAO25_02970)	gcvT	556687..557778 (+)	1092	WP_000093349.1	glycine cleavage system aminomethyltransferase GcvT	-
QAO25_RS02975 (QAO25_02975)	gcvPA	557798..559144 (+)	1347	WP_000019693.1	aminomethyl-transferring glycine dehydrogenase subunit GcvPA	-

Sequence

Protein

• Length: 103 a.a.
• Molecular weight: 11315.36 Da
• Isoelectric Point: 8.5268

>NTDB_id=746443 QAO25_RS02940 WP_000472256.1 554335..554646(+) (comGC) [Staphylococcus aureus strain MRSA-COL]
MFKFLKKTQAFTLIEMLLVLLIISLLLILIIPNIAKQTAHIQSTGCNAQVKMVNSQIEAYALKHNRNPSSIEDLIADGFI
KEAQKTCKSGETITISNGEAVAN

Nucleotide

• Length: 312 bp

>NTDB_id=746443 QAO25_RS02940 WP_000472256.1 554335..554646(+) (comGC) [Staphylococcus aureus strain MRSA-COL]
ATGTTTAAATTTCTTAAGAAAACTCAAGCGTTTACATTGATAGAGATGCTATTAGTGTTATTAATCATCAGTTTATTATT
AATTTTAATCATTCCAAATATTGCTAAACAAACTGCTCACATACAATCAACAGGTTGTAATGCACAGGTAAAAATGGTTA
ATAGTCAAATTGAAGCGTATGCATTGAAACATAATAGAAATCCATCGTCTATTGAAGACTTAATTGCAGATGGTTTTATA
AAAGAAGCACAAAAGACATGTAAATCAGGAGAGACAATCACAATTAGTAATGGAGAAGCAGTTGCAAATTAG

Domains

Predicted by InterProScan.

• Prokaryotic N-terminal methylation motif (N_methyl) (6-30)

3D structure

• AlphaFold DB: A0A0H2XGS7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGC	Staphylococcus aureus MW2	100	100	1
comGC	Staphylococcus aureus N315	100	100	1
comGC/cglC	Streptococcus pneumoniae TIGR4	46.078	99.029	0.456
comGC/cglC	Streptococcus pneumoniae Rx1	46.078	99.029	0.456
comGC/cglC	Streptococcus pneumoniae D39	46.078	99.029	0.456
comGC/cglC	Streptococcus pneumoniae R6	46.078	99.029	0.456
comGC/cglC	Streptococcus mitis SK321	51.163	83.495	0.427
comGC/cglC	Streptococcus mitis NCTC 12261	51.163	83.495	0.427
comGC	Streptococcus gordonii str. Challis substr. CH1	42.857	95.146	0.408
comGC	Streptococcus suis isolate S10	50	75.728	0.379
comGC	Bacillus subtilis subsp. subtilis str. 168	41.758	88.35	0.369
comGC	Lactococcus lactis subsp. cremoris KW2	46.341	79.612	0.369