Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA   Type   Machinery gene
Locus tag   QJ120_RS10680 Genome accession   NZ_AP019759
Coordinates   1903934..1904860 (+) Length   308 a.a.
NCBI ID   WP_010958587.1    Uniprot ID   Q83AA7
Organism   Coxiella burnetii strain VS42     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 1898934..1909860
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QJ120_RS10635 (CBUVS42_C19120) - 1899527..1899799 (-) 273 WP_010957319.1 hypothetical protein -
  QJ120_RS10640 - 1899800..1899928 (+) 129 WP_230578144.1 hypothetical protein -
  QJ120_RS10645 (CBUVS42_C19130) - 1899989..1900243 (+) 255 WP_005769716.1 type II toxin-antitoxin system prevent-host-death family antitoxin -
  QJ120_RS10650 (CBUVS42_C19140) - 1900243..1900518 (+) 276 WP_005769718.1 Txe/YoeB family addiction module toxin -
  QJ120_RS10655 (CBUVS42_C19150) - 1900491..1900976 (-) 486 WP_005769725.1 dihydrofolate reductase -
  QJ120_RS10660 (CBUVS42_C19160) - 1900973..1901776 (-) 804 WP_010958584.1 epoxyqueuosine reductase QueH -
  QJ120_RS10665 (CBUVS42_C19170) - 1901972..1902259 (+) 288 WP_010958585.1 acylphosphatase -
  QJ120_RS10670 (CBUVS42_C19180) gmhB 1902235..1902789 (-) 555 WP_005769732.1 D-glycero-beta-D-manno-heptose 1,7-bisphosphate 7-phosphatase -
  QJ120_RS10675 (CBUVS42_C19190) fmt 1902802..1903746 (-) 945 WP_010958586.1 methionyl-tRNA formyltransferase -
  QJ120_RS10680 (CBUVS42_C19200) dprA 1903934..1904860 (+) 927 WP_010958587.1 DNA-processing protein DprA Machinery gene
  QJ120_RS10685 (CBUVS42_C19210) - 1904857..1905336 (+) 480 WP_010958588.1 DUF494 domain-containing protein -
  QJ120_RS10690 (CBUVS42_C19220) topA 1905339..1907636 (+) 2298 WP_010958589.1 type I DNA topoisomerase -
  QJ120_RS10695 (CBUVS42_C19230) - 1907643..1907813 (-) 171 WP_010958590.1 hypothetical protein -
  QJ120_RS10700 (CBUVS42_C19240) purE 1907844..1908344 (+) 501 WP_005769750.1 5-(carboxyamino)imidazole ribonucleotide mutase -
  QJ120_RS10705 (CBUVS42_C19250) - 1908347..1908907 (+) 561 WP_005769752.1 L-threonylcarbamoyladenylate synthase -
  QJ120_RS10710 - 1908957..1909076 (+) 120 Protein_2091 hypothetical protein -
  QJ120_RS10715 (CBUVS42_C19260) - 1909350..1909490 (+) 141 WP_010958591.1 hypothetical protein -

Sequence

Protein


Download         Length: 308 a.a.        Molecular weight: 33018.28 Da        Isoelectric Point: 7.5121

>NTDB_id=73884 QJ120_RS10680 WP_010958587.1 1903934..1904860(+) (dprA) [Coxiella burnetii strain VS42]
MQPPFNALLFFAMPNSQLDPEWTTAPNHHILTLDHPSYPTLLKEIPDPPKKLYIMGDPLILNQPQFAIVGSRNPTVTGCE
IAQEMAEKLVQAGFHITSGLALGIDAASHRGALKAGGQTIAVLGSGLTNIYPPRHHRLAEQISQKGALVSEFPLTMPPLP
TNFPRRNRIIIGLSLGTLVVEATLGSGSLITAKLAAEQNREVFAIPGSIRNPLSQGCHALIKEGAKLVDSIGDIIAELSY
EATGASAPIQALDKNEHKLLECIGFEVTSIDQLIARSGFSASIVASLLLRIELQGYIKSRPGGVIRVK

Nucleotide


Download         Length: 927 bp        

>NTDB_id=73884 QJ120_RS10680 WP_010958587.1 1903934..1904860(+) (dprA) [Coxiella burnetii strain VS42]
TTGCAACCTCCCTTCAATGCACTATTATTTTTCGCCATGCCAAATTCTCAATTAGACCCAGAATGGACGACAGCGCCGAA
CCACCATATTTTGACGCTCGATCATCCCTCCTACCCTACTTTATTGAAGGAAATCCCCGATCCGCCCAAAAAGCTCTACA
TCATGGGTGACCCTTTGATATTAAATCAGCCGCAATTTGCCATCGTCGGCAGCCGTAATCCAACCGTCACCGGCTGCGAA
ATCGCACAAGAAATGGCAGAGAAACTCGTTCAAGCTGGTTTTCACATCACCAGCGGCCTTGCACTTGGCATCGATGCCGC
AAGTCACCGCGGGGCTTTAAAAGCAGGAGGCCAAACCATAGCCGTACTCGGCAGCGGCTTAACTAACATATATCCTCCAC
GCCACCACCGTCTGGCGGAACAAATTTCCCAAAAAGGCGCCCTCGTCTCAGAATTCCCGCTAACCATGCCGCCACTCCCC
ACCAACTTCCCTCGCCGCAACCGCATCATCATCGGATTAAGCCTCGGTACGCTCGTGGTGGAAGCTACCCTTGGCTCAGG
CTCTCTGATCACCGCGAAATTAGCCGCCGAACAAAACCGGGAAGTTTTCGCCATCCCGGGTTCAATCCGAAACCCTCTTT
CTCAGGGATGCCATGCTCTCATCAAAGAGGGCGCTAAACTGGTTGATTCTATAGGGGATATTATTGCAGAATTGAGTTAT
GAGGCTACGGGCGCTAGCGCCCCGATTCAAGCACTTGATAAGAATGAACACAAACTGTTAGAGTGCATCGGATTTGAGGT
CACTTCCATTGATCAACTGATCGCTCGAAGTGGCTTTTCGGCTTCCATCGTAGCTTCGTTATTGTTAAGGATAGAATTGC
AAGGCTACATTAAATCAAGACCTGGCGGTGTTATACGAGTGAAGTGA

Domains

Predicted by InterproScan.

DNA recombination-mediator protein A (DNA_processg_A)

(25-229)

DprA winged helix domain (DprA_WH)

(245-303)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q83AA7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA Legionella pneumophila strain ERS1305867

53.925

95.13

0.513
  dprA Vibrio cholerae strain A1552

48.829

97.078

0.474
  dprA Vibrio campbellii strain DS40M4

47.386

99.351

0.471
  dprA Glaesserella parasuis strain SC1401

44.951

99.675

0.448
  dprA Acinetobacter baumannii D1279779

44.369

95.13

0.422
  dprA Acinetobacter baumannii strain A118

43.878

95.455

0.419
  dprA Acinetobacter baylyi ADP1

42.712

95.779

0.409
  dprA Haemophilus influenzae Rd KW20

55.046

70.779

0.39
  dprA Neisseria meningitidis strain C311

48.684

74.026

0.36
  dprA Neisseria meningitidis MC58

48.684

74.026

0.36

Multiple sequence alignment