Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   N2A95_RS01975 Genome accession   NZ_CP104190
Coordinates   406630..407571 (+) Length   313 a.a.
NCBI ID   WP_003108751.1    Uniprot ID   -
Organism   Streptococcus parauberis strain HFTC0064     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 401630..412571
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  N2A95_RS01965 (N2A95_01965) rpoC 402466..406098 (+) 3633 WP_279386803.1 DNA-directed RNA polymerase subunit beta' -
  N2A95_RS01970 (N2A95_01970) - 406202..406576 (+) 375 WP_003108753.1 DUF1033 family protein -
  N2A95_RS01975 (N2A95_01975) comYA 406630..407571 (+) 942 WP_003108751.1 competence type IV pilus ATPase ComGA Machinery gene
  N2A95_RS01980 (N2A95_01980) comYB 407483..408538 (+) 1056 WP_152414240.1 competence type IV pilus assembly protein ComGB Machinery gene
  N2A95_RS01985 (N2A95_01985) comYC 408535..408861 (+) 327 WP_004347181.1 competence type IV pilus major pilin ComGC Machinery gene
  N2A95_RS01990 (N2A95_01990) comGD 408851..409258 (+) 408 WP_243619590.1 competence type IV pilus minor pilin ComGD -
  N2A95_RS01995 (N2A95_01995) comGE 409230..409529 (+) 300 WP_003108643.1 competence type IV pilus minor pilin ComGE -
  N2A95_RS02000 (N2A95_02000) comGF 409507..409944 (+) 438 WP_003102915.1 competence type IV pilus minor pilin ComGF -
  N2A95_RS02005 (N2A95_02005) comGG 409973..410419 (+) 447 WP_238570152.1 competence type IV pilus minor pilin ComGG -
  N2A95_RS02010 (N2A95_02010) comYH 410526..411482 (+) 957 WP_003103712.1 class I SAM-dependent methyltransferase Machinery gene

Sequence

Protein


Download         Length: 313 a.a.        Molecular weight: 36265.62 Da        Isoelectric Point: 6.5048

>NTDB_id=727926 N2A95_RS01975 WP_003108751.1 406630..407571(+) (comYA) [Streptococcus parauberis strain HFTC0064]
MIQGLGKQIISEAMELQVQDIYILPEENGYQLFFRIHDERQKLENFQTSQLQQLMSHFKFLAGMNVGEKRRCQLGSCNYD
IDDSISISLRLSTVGDYRGRESMVIRILYPYQENQTYWEDMDEKINQFIIGRGLYLFAGPVGSGKTSLMYRLIEKNFHDR
QVITIEDPVEIKNPKFLQLQVNDSIGMTYDNLIKLSLRHRPDILVIGEIRDRETAQAVIRASLTGIMVFSTVHAKSIPGV
YYRLLELGINQNELENALRLIVYQRLMGGKGLIDFTNKNYISHSHEKWNQAIDQLVAKGHFPEEKGEKEKIIE

Nucleotide


Download         Length: 942 bp        

>NTDB_id=727926 N2A95_RS01975 WP_003108751.1 406630..407571(+) (comYA) [Streptococcus parauberis strain HFTC0064]
ATGATCCAAGGTTTGGGTAAGCAAATAATAAGTGAAGCGATGGAGTTGCAAGTTCAAGATATCTATATTTTACCTGAAGA
GAATGGGTATCAATTGTTTTTCCGAATTCATGATGAAAGGCAAAAATTAGAAAATTTTCAAACAAGTCAATTACAACAAT
TAATGAGTCATTTTAAGTTTTTGGCTGGTATGAATGTTGGCGAAAAAAGAAGGTGTCAGTTAGGTTCTTGTAATTATGAT
ATAGATGATTCTATATCAATCTCATTAAGACTTTCTACAGTTGGTGATTATCGTGGGCGTGAAAGTATGGTTATTCGTAT
TCTTTATCCTTATCAAGAGAATCAAACCTATTGGGAGGATATGGATGAAAAAATTAATCAATTTATAATCGGACGTGGAC
TCTATCTTTTTGCTGGACCAGTTGGATCAGGTAAAACAAGTCTAATGTATAGACTTATTGAGAAAAATTTCCATGACAGG
CAAGTGATTACGATTGAGGATCCAGTTGAAATAAAGAATCCCAAATTCTTACAATTACAAGTTAATGATAGTATTGGAAT
GACTTATGATAATCTCATAAAGTTATCTCTGCGTCATCGACCGGATATTTTAGTAATTGGTGAAATTCGAGATAGGGAGA
CTGCACAGGCTGTGATTAGAGCAAGTTTAACAGGAATTATGGTCTTTTCAACAGTACATGCAAAAAGTATTCCAGGGGTA
TATTATCGCCTTTTAGAATTAGGAATTAATCAAAATGAATTAGAAAACGCCTTAAGATTAATAGTTTATCAAAGATTAAT
GGGAGGGAAAGGTTTAATTGATTTTACTAACAAAAACTATATTAGTCATTCGCATGAAAAATGGAATCAAGCTATTGATC
AGTTGGTTGCAAAAGGACATTTCCCTGAAGAAAAAGGGGAAAAAGAAAAGATTATCGAGTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(8-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus mutans UA159

61.218

99.681

0.61
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

61.29

99.042

0.607
  comYA Streptococcus mutans UA140

60.897

99.681

0.607
  comYA Streptococcus gordonii str. Challis substr. CH1

57.235

99.361

0.569
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

56.09

99.681

0.559
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

56.09

99.681

0.559
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

56.09

99.681

0.559
  comGA/cglA/cilD Streptococcus pneumoniae D39

56.09

99.681

0.559
  comGA/cglA/cilD Streptococcus pneumoniae R6

56.09

99.681

0.559
  comGA Lactococcus lactis subsp. cremoris KW2

51.447

99.361

0.511
  comGA Latilactobacillus sakei subsp. sakei 23K

42.545

87.859

0.374