Detailed information NTG0727927

Bioinformatically predicted

Overview

• Name: comYB
• Type: Machinery gene
• Locus tag: N2A95_RS01980
• Genome accession: NZ_CP104190
• Coordinates: 407483..408538 (+)
• Length: 351 a.a.
• NCBI ID: WP_152414240.1
• Uniprot ID: -
• Organism: Streptococcus parauberis strain HFTC0064
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 402483..413538

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
N2A95_RS01970 (N2A95_01970)	-	406202..406576 (+)	375	WP_003108753.1	DUF1033 family protein	-
N2A95_RS01975 (N2A95_01975)	comYA	406630..407571 (+)	942	WP_003108751.1	competence type IV pilus ATPase ComGA	Machinery gene
N2A95_RS01980 (N2A95_01980)	comYB	407483..408538 (+)	1056	WP_152414240.1	competence type IV pilus assembly protein ComGB	Machinery gene
N2A95_RS01985 (N2A95_01985)	comYC	408535..408861 (+)	327	WP_004347181.1	competence type IV pilus major pilin ComGC	Machinery gene
N2A95_RS01990 (N2A95_01990)	comGD	408851..409258 (+)	408	WP_243619590.1	competence type IV pilus minor pilin ComGD	-
N2A95_RS01995 (N2A95_01995)	comGE	409230..409529 (+)	300	WP_003108643.1	competence type IV pilus minor pilin ComGE	-
N2A95_RS02000 (N2A95_02000)	comGF	409507..409944 (+)	438	WP_003102915.1	competence type IV pilus minor pilin ComGF	-
N2A95_RS02005 (N2A95_02005)	comGG	409973..410419 (+)	447	WP_238570152.1	competence type IV pilus minor pilin ComGG	-
N2A95_RS02010 (N2A95_02010)	comYH	410526..411482 (+)	957	WP_003103712.1	class I SAM-dependent methyltransferase	Machinery gene
N2A95_RS02015 (N2A95_02015)	-	411538..412731 (+)	1194	WP_003108638.1	acetate kinase	-
N2A95_RS02020 (N2A95_02020)	-	412842..413054 (+)	213	WP_003108636.1	helix-turn-helix transcriptional regulator	-
N2A95_RS02025 (N2A95_02025)	-	413047..413499 (+)	453	WP_003108634.1	hypothetical protein	-

Sequence

Protein

• Length: 351 a.a.
• Molecular weight: 40401.42 Da
• Isoelectric Point: 9.8078

>NTDB_id=727927 N2A95_RS01980 WP_152414240.1 407483..408538(+) (comYB) [Streptococcus parauberis strain HFTC0064]
MKNGIKLLISWLQKDISLKKKGKKKRLSSKKQYQLIQLLHNLQASGFNLVEMVSFLKKSKLISEEQVKIMEFHMLNGSSL
SKIMLDLGYPDSIITQLSLAELHGNILGSLENIETYLLQVNHIKKKTFEVVMYPLVLLFFLTTILLGLRQYLLPSLNEEG
PLMFLLTYFPHLLIILIVIILFVSIVVIYKWRHSSPLKLISQISRLPLIGYVIQLYMTAFYAREWGNLLDQGLELSTILS
VMSKEKSLLVREIGIEMNSAFVEGIPFEQKVLDYPFFKNELSLIISYGQVKSKLGKELEIYSQNTWESYFRFLIQLTQLI
QPIVFLAVALIIVMIYAAMLLPIYQNMGGNL

Nucleotide

• Length: 1056 bp

>NTDB_id=727927 N2A95_RS01980 WP_152414240.1 407483..408538(+) (comYB) [Streptococcus parauberis strain HFTC0064]
ATGAAAAATGGAATCAAGCTATTGATCAGTTGGTTGCAAAAGGACATTTCCCTGAAGAAAAAGGGGAAAAAGAAAAGATT
ATCGAGTAAAAAACAATATCAACTTATCCAATTGTTACATAATCTCCAAGCAAGCGGATTTAATTTAGTTGAAATGGTAT
CTTTTCTGAAGAAAAGTAAATTAATATCTGAAGAGCAGGTTAAAATTATGGAATTTCACATGCTCAATGGCAGTAGTTTA
TCAAAAATCATGCTTGATTTAGGTTACCCAGATAGTATTATAACTCAATTGAGTTTAGCAGAATTACATGGGAATATTTT
GGGGAGTCTTGAAAATATAGAAACATACCTTTTGCAAGTGAATCATATTAAAAAGAAAACTTTCGAAGTGGTAATGTATC
CACTTGTATTACTATTTTTTCTAACAACTATACTACTTGGTTTGAGACAATATTTATTGCCTTCGCTTAATGAGGAAGGT
CCACTTATGTTCCTACTAACCTATTTTCCTCACCTTTTAATAATCCTAATTGTGATAATCCTCTTTGTCTCTATAGTAGT
TATTTATAAATGGCGACACAGTTCACCACTCAAGCTAATTAGCCAAATTAGTCGATTGCCTTTAATAGGATACGTCATCC
AGTTATATATGACAGCCTTCTATGCTCGAGAATGGGGAAATTTATTAGATCAGGGGCTTGAATTAAGTACGATTTTGTCT
GTTATGAGTAAGGAAAAATCACTTTTGGTACGGGAAATAGGTATAGAAATGAATAGTGCTTTTGTAGAGGGGATTCCGTT
TGAGCAAAAGGTACTAGATTATCCATTTTTTAAAAATGAATTGAGTTTAATTATTTCATATGGACAAGTTAAATCAAAAT
TAGGGAAGGAGTTAGAAATATATTCTCAAAATACATGGGAGTCTTACTTCAGGTTCCTCATACAACTTACTCAGCTGATT
CAACCAATTGTATTTTTAGCAGTTGCTCTAATTATTGTCATGATTTATGCAGCAATGCTATTGCCAATTTATCAAAATAT
GGGAGGAAATTTATGA

Domains

Predicted by InterproScan.

• Type II secretion system (T2SS), protein F (T2SSF) (36-154)

• Type II secretion system (T2SS), protein F (T2SSF) (222-342)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYB	Streptococcus mutans UA140	51.304	98.291	0.504
comYB	Streptococcus mutans UA159	51.304	98.291	0.504
comYB	Streptococcus gordonii str. Challis substr. CH1	46.765	96.866	0.453
comGB/cglB	Streptococcus mitis NCTC 12261	46.471	96.866	0.45
comGB/cglB	Streptococcus mitis SK321	45.104	96.011	0.433
comGB/cglB	Streptococcus pneumoniae Rx1	44.807	96.011	0.43
comGB/cglB	Streptococcus pneumoniae D39	44.807	96.011	0.43
comGB/cglB	Streptococcus pneumoniae R6	44.807	96.011	0.43
comGB/cglB	Streptococcus pneumoniae TIGR4	44.807	96.011	0.43
comGB	Lactococcus lactis subsp. cremoris KW2	42.229	97.151	0.41