Detailed information NTG0726679

Bioinformatically predicted

Overview

• Name: endA
• Type: Machinery gene
• Locus tag: P1I87_RS07725
• Genome accession: NZ_CP119576
• Coordinates: 1508328..1509113 (-)
• Length: 261 a.a.
• NCBI ID: WP_000825431.1
• Uniprot ID: Q8E0P2
• Organism: Streptococcus agalactiae strain Guangzhou-SAG092
• Function: cleavage of dsDNA into ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1503328..1514113

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
P1I87_RS07700 (P1I87_07700)	-	1504066..1504950 (+)	885	WP_000354840.1	LysR family transcriptional regulator	-
P1I87_RS07705 (P1I87_07705)	-	1504987..1505805 (-)	819	WP_000601007.1	hypothetical protein	-
P1I87_RS07710 (P1I87_07710)	fetB	1505969..1506742 (-)	774	WP_000011926.1	iron export ABC transporter permease subunit FetB	-
P1I87_RS07715 (P1I87_07715)	-	1506739..1507395 (-)	657	WP_000121094.1	ATP-binding cassette domain-containing protein	-
P1I87_RS07720 (P1I87_07720)	-	1507612..1508250 (+)	639	WP_000478529.1	VTT domain-containing protein	-
P1I87_RS07725 (P1I87_07725)	endA	1508328..1509113 (-)	786	WP_000825431.1	DNA/RNA non-specific endonuclease	Machinery gene
P1I87_RS07730 (P1I87_07730)	-	1509374..1510819 (+)	1446	WP_000750930.1	FAD/NAD(P)-binding protein	-
P1I87_RS07735 (P1I87_07735)	-	1510876..1511547 (-)	672	WP_000891267.1	ABC transporter ATP-binding protein	-
P1I87_RS07740 (P1I87_07740)	-	1511644..1511964 (-)	321	WP_001865677.1	hypothetical protein	-
P1I87_RS07745 (P1I87_07745)	-	1511973..1512101 (-)	129	WP_000962057.1	hypothetical protein	-
P1I87_RS07750 (P1I87_07750)	-	1512202..1512468 (-)	267	WP_001865676.1	hypothetical protein	-
P1I87_RS07755 (P1I87_07755)	-	1512553..1512996 (-)	444	Protein_1453	hypothetical protein	-

Sequence

Protein

• Length: 261 a.a.
• Molecular weight: 29424.86 Da
• Isoelectric Point: 8.9989

>NTDB_id=726679 P1I87_RS07725 WP_000825431.1 1508328..1509113(-) (endA) [Streptococcus agalactiae strain Guangzhou-SAG092]
MKRLHKLFITVIATLGMLGVMTFGLPTQPQNVTPIVHADVNSSVDTSQEFQNNLKNAIGNLPFQYVNGIYELNNNQTNLN
ADVNVKAYVQNTIDNQQRLSTANAMLDRTIRQYQNRRDTTLPDANWKPLGWHQVATNDHYGHAVDKGHLIAYALAGNFKG
WDASVSNPQNVVTQTAHSNQSNQKINRGQNYYESLVRKAVDQNKRVRYRVTPLYRNDTDLVPFAMHLEAKSQDGTLEFNV
AIPNTQASYTMDYATGEITLN

Nucleotide

• Length: 786 bp

>NTDB_id=726679 P1I87_RS07725 WP_000825431.1 1508328..1509113(-) (endA) [Streptococcus agalactiae strain Guangzhou-SAG092]
ATGAAAAGATTACATAAACTGTTTATAACCGTAATTGCTACATTAGGTATGTTGGGGGTAATGACCTTTGGTCTTCCAAC
GCAGCCGCAAAACGTAACGCCGATAGTACATGCTGATGTCAATTCATCTGTTGATACGAGCCAGGAATTTCAAAATAATT
TAAAAAATGCTATTGGTAACCTACCATTTCAATATGTTAATGGTATTTATGAATTAAATAATAATCAGACAAATTTAAAT
GCTGATGTCAATGTTAAAGCGTATGTTCAAAATACAATTGACAATCAACAAAGACTATCAACTGCTAATGCAATGCTTGA
TAGAACCATTCGTCAATATCAAAATCGCAGAGATACCACTCTTCCCGATGCAAATTGGAAACCATTAGGTTGGCATCAAG
TAGCTACTAATGACCATTATGGACATGCAGTCGACAAGGGGCATTTAATTGCCTATGCTTTAGCTGGAAATTTCAAAGGT
TGGGATGCTTCCGTGTCAAATCCTCAAAATGTTGTCACACAAACAGCTCATTCCAACCAATCAAATCAAAAAATCAATCG
TGGACAAAATTATTATGAAAGCTTAGTTCGTAAGGCGGTTGACCAAAACAAACGTGTTCGTTACCGTGTAACTCCATTGT
ACCGTAATGATACTGATTTAGTTCCATTTGCAATGCACCTAGAAGCTAAATCACAAGATGGCACATTAGAATTTAATGTT
GCTATTCCAAACACACAAGCATCATACACTATGGATTATGCAACAGGAGAAATAACACTAAATTAA

Domains

Predicted by InterProScan.

• DNA/RNA non-specific endonuclease (Endonuclease_NS) (77-235)

3D structure

• AlphaFold DB: Q8E0P2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
endA	Streptococcus pneumoniae Rx1	51.515	75.862	0.391
endA	Streptococcus pneumoniae D39	51.515	75.862	0.391
endA	Streptococcus pneumoniae R6	51.515	75.862	0.391
endA	Streptococcus pneumoniae TIGR4	51.515	75.862	0.391