Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGA/cglA   Type   Machinery gene
Locus tag   MGCS35922_RS00785 Genome accession   NZ_CP118097
Coordinates   126756..127697 (+) Length   313 a.a.
NCBI ID   WP_014611930.1    Uniprot ID   -
Organism   Streptococcus dysgalactiae subsp. equisimilis strain MGCS35922     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 121756..132697
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MGCS35922_RS00775 (MGCS35922_00318) rpoC 122466..126107 (+) 3642 WP_037589802.1 DNA-directed RNA polymerase subunit beta' -
  MGCS35922_RS00780 (MGCS35922_00320) - 126310..126675 (+) 366 WP_003055257.1 DUF1033 family protein -
  MGCS35922_RS00785 (MGCS35922_00322) comGA/cglA 126756..127697 (+) 942 WP_014611930.1 competence type IV pilus ATPase ComGA Machinery gene
  MGCS35922_RS00790 (MGCS35922_00324) comGB 127633..128664 (+) 1032 WP_084916952.1 competence type IV pilus assembly protein ComGB Machinery gene
  MGCS35922_RS00795 (MGCS35922_00326) comGC 128666..128992 (+) 327 WP_084916953.1 competence type IV pilus major pilin ComGC Machinery gene
  MGCS35922_RS00800 (MGCS35922_00328) comGD 128967..129395 (+) 429 WP_257638821.1 competence type IV pilus minor pilin ComGD Machinery gene
  MGCS35922_RS00805 (MGCS35922_00330) comGE 129403..129648 (+) 246 WP_049519695.1 competence type IV pilus minor pilin ComGE Machinery gene
  MGCS35922_RS00810 (MGCS35922_00332) comGF 129629..130069 (+) 441 WP_003061780.1 competence type IV pilus minor pilin ComGF Machinery gene
  MGCS35922_RS00815 (MGCS35922_00334) comGG 130098..130421 (+) 324 WP_227985720.1 competence type IV pilus minor pilin ComGG -
  MGCS35922_RS00820 (MGCS35922_00336) comGH 130484..131437 (+) 954 WP_003060701.1 class I SAM-dependent methyltransferase Machinery gene
  MGCS35922_RS00825 (MGCS35922_00338) - 131496..132692 (+) 1197 WP_275926357.1 acetate kinase -

Sequence

Protein


Download         Length: 313 a.a.        Molecular weight: 35165.29 Da        Isoelectric Point: 7.5610

>NTDB_id=721282 MGCS35922_RS00785 WP_014611930.1 126756..127697(+) (comGA/cglA) [Streptococcus dysgalactiae subsp. equisimilis strain MGCS35922]
MVQALARSILKEAEQIQAQDIYILPKENQYELLIRVGDERRLVDVYRGDRMAHLISHFKFVAGMTVGEKRRCQVGSCDYD
IGGDTLLSLRLSSVGNYRGQESLVIRLLHHQQRSLHYWFDGLKTVARQIGGRGLYLFAGPVGSGKTTLMHQLIADYYQGA
QVISIEDPVEIKNHQALQLQVNDSIGMTYDNLIKLSLRHRPDILIIGEIRDSQTARAVIRASLTGVLVFSTVHAKSISGV
YARLLELGVTRAELDNCLALVAYQRLLNGGALIDSTQTEFEHYSPNQWNQKIDDLLAAGHLSPEQARFEKIIQ

Nucleotide


Download         Length: 942 bp        

>NTDB_id=721282 MGCS35922_RS00785 WP_014611930.1 126756..127697(+) (comGA/cglA) [Streptococcus dysgalactiae subsp. equisimilis strain MGCS35922]
ATGGTACAAGCATTAGCAAGATCTATTTTGAAAGAAGCTGAGCAGATTCAAGCTCAAGATATCTATATTTTGCCAAAGGA
AAATCAGTATGAGCTATTGATAAGGGTAGGAGATGAAAGGAGATTGGTGGATGTTTATCGGGGCGATCGGATGGCTCATC
TTATTAGTCACTTTAAGTTCGTTGCAGGAATGACCGTTGGTGAGAAACGACGCTGTCAAGTCGGTTCTTGTGATTATGAT
ATCGGTGGAGACACACTTTTGTCTCTACGCCTGTCTAGTGTTGGAAATTACCGTGGACAAGAGAGCCTAGTGATTCGGTT
ATTACATCATCAACAAAGAAGTTTACATTACTGGTTTGACGGACTGAAAACAGTTGCACGTCAGATTGGAGGCCGAGGAC
TCTATCTTTTTGCAGGTCCAGTCGGATCAGGCAAAACGACTTTGATGCACCAATTGATTGCTGATTATTATCAAGGAGCA
CAGGTCATTAGCATAGAAGATCCGGTGGAAATTAAAAATCATCAAGCGCTCCAATTACAAGTTAATGATAGTATTGGCAT
GACTTACGACAACTTGATCAAACTATCTTTACGGCATCGCCCTGATATTTTAATCATTGGTGAAATTCGAGACAGCCAGA
CAGCTAGAGCGGTTATTAGAGCAAGTTTAACAGGTGTCTTAGTATTTTCAACAGTTCATGCCAAAAGCATTTCTGGTGTT
TATGCCAGATTACTAGAACTAGGAGTGACAAGAGCAGAATTAGACAATTGTTTGGCTTTGGTTGCTTACCAACGATTGCT
TAATGGAGGAGCATTGATTGACTCAACTCAAACAGAATTTGAACACTACTCACCAAACCAATGGAATCAGAAAATTGATG
ACCTTCTTGCAGCGGGACATCTCAGTCCGGAGCAAGCAAGGTTTGAAAAAATTATCCAGTAA

Domains

Predicted by InterProScan.

Type II/IV secretion system protein (T2SSE)

(9-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

61.935

99.042

0.613
  comGA Streptococcus mutans UA140

61.415

99.361

0.61
  comGA Streptococcus mutans UA159

61.415

99.361

0.61
  comGA Streptococcus gordonii str. Challis substr. CH1

60.772

99.361

0.604
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

59.807

99.361

0.594
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

59.486

99.361

0.591
  comGA/cglA/cilD Streptococcus pneumoniae D39

59.486

99.361

0.591
  comGA/cglA/cilD Streptococcus pneumoniae R6

59.486

99.361

0.591
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

59.486

99.361

0.591
  comGA Lactococcus lactis subsp. cremoris KW2

52.412

99.361

0.521
  comGA Latilactobacillus sakei subsp. sakei 23K

38.908

93.61

0.364