Detailed information NTG0721283

Bioinformatically predicted

Overview

• Name: comGB
• Type: Machinery gene
• Locus tag: MGCS35922_RS00790
• Genome accession: NZ_CP118097
• Coordinates: 127633..128664 (+)
• Length: 343 a.a.
• NCBI ID: WP_084916952.1
• Uniprot ID: -
• Organism: Streptococcus dysgalactiae subsp. equisimilis strain MGCS35922
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 122633..133664

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MGCS35922_RS00780 (MGCS35922_00320)	-	126310..126675 (+)	366	WP_003055257.1	DUF1033 family protein	-
MGCS35922_RS00785 (MGCS35922_00322)	comGA/cglA	126756..127697 (+)	942	WP_014611930.1	competence type IV pilus ATPase ComGA	Machinery gene
MGCS35922_RS00790 (MGCS35922_00324)	comGB	127633..128664 (+)	1032	WP_084916952.1	competence type IV pilus assembly protein ComGB	Machinery gene
MGCS35922_RS00795 (MGCS35922_00326)	comGC	128666..128992 (+)	327	WP_084916953.1	competence type IV pilus major pilin ComGC	Machinery gene
MGCS35922_RS00800 (MGCS35922_00328)	comGD	128967..129395 (+)	429	WP_257638821.1	competence type IV pilus minor pilin ComGD	Machinery gene
MGCS35922_RS00805 (MGCS35922_00330)	comGE	129403..129648 (+)	246	WP_049519695.1	competence type IV pilus minor pilin ComGE	Machinery gene
MGCS35922_RS00810 (MGCS35922_00332)	comGF	129629..130069 (+)	441	WP_003061780.1	competence type IV pilus minor pilin ComGF	Machinery gene
MGCS35922_RS00815 (MGCS35922_00334)	comGG	130098..130421 (+)	324	WP_227985720.1	competence type IV pilus minor pilin ComGG	-
MGCS35922_RS00820 (MGCS35922_00336)	comGH	130484..131437 (+)	954	WP_003060701.1	class I SAM-dependent methyltransferase	Machinery gene
MGCS35922_RS00825 (MGCS35922_00338)	-	131496..132692 (+)	1197	WP_275926357.1	acetate kinase	-
MGCS35922_RS00830 (MGCS35922_00340)	-	132999..133205 (+)	207	WP_003058508.1	helix-turn-helix transcriptional regulator	-

Sequence

Protein

• Length: 343 a.a.
• Molecular weight: 38965.39 Da
• Isoelectric Point: 9.2055

>NTDB_id=721283 MGCS35922_RS00790 WP_084916952.1 127633..128664(+) (comGB) [Streptococcus dysgalactiae subsp. equisimilis strain MGCS35922]
MTFLQRDISVRSKQGLKKLSSKEQYKLIQLLANLLLTGFNLAEIIAFLTKSHLIPEPYVLRMEEALLKGRGLADMLAGIG
FSDAILTQISLADGHGNIETTLVNIQGYLNQMAKLKRKTIEVVTYPIILLVFLFVMILGLRHYVMPQLEAQNQLTIFLTH
FPAIFFGIILFIGVLLGGIWLHWRSQSRLKLFIHFSAYPVLGKLLQQYLTAYYAREWGTLIGQGLELPVILDIMAMEKSL
FMQELAEDIRVSLLAGQAFHDKVATYPFFKKELSLMITYGEIKSKLGSELEIYAQESWTQFFSQLHQATQFIQPIIFLVI
ALTIVMIYAAILLPIYQNMGGVL

Nucleotide

• Length: 1032 bp

>NTDB_id=721283 MGCS35922_RS00790 WP_084916952.1 127633..128664(+) (comGB) [Streptococcus dysgalactiae subsp. equisimilis strain MGCS35922]
ATGACCTTCTTGCAGCGGGACATCTCAGTCCGGAGCAAGCAAGGTTTGAAAAAATTATCCAGTAAGGAACAATACAAACT
AATTCAGCTATTAGCTAACCTTTTGTTAACAGGATTTAACTTGGCTGAGATAATAGCTTTCTTAACAAAAAGTCATTTGA
TTCCCGAGCCCTATGTTCTCCGCATGGAAGAAGCACTCTTAAAAGGTCGAGGGCTGGCAGATATGTTAGCTGGGATAGGT
TTTTCGGATGCTATTTTAACTCAAATTAGTTTAGCAGATGGTCACGGAAACATTGAGACGACGCTTGTTAATATTCAGGG
CTATCTCAACCAAATGGCTAAACTTAAACGAAAAACCATTGAAGTCGTCACCTATCCGATTATTCTCCTGGTATTTCTTT
TTGTGATGATATTAGGGTTAAGGCATTATGTTATGCCTCAATTAGAAGCTCAAAATCAGCTTACTATTTTTCTGACTCAT
TTTCCAGCTATTTTCTTTGGTATTATCCTTTTTATAGGTGTGCTGTTAGGGGGAATTTGGCTGCATTGGCGATCGCAAAG
TCGCCTCAAGCTTTTTATTCACTTCAGTGCTTATCCTGTTTTAGGGAAACTCTTACAACAGTATCTGACGGCTTATTATG
CTAGAGAATGGGGAACATTGATTGGACAGGGACTTGAATTACCAGTCATTCTGGATATTATGGCCATGGAGAAATCTTTA
TTCATGCAAGAATTGGCTGAAGATATTCGAGTTAGTTTATTGGCAGGACAAGCTTTTCATGATAAGGTAGCTACCTATCC
TTTCTTTAAAAAAGAGTTAAGTTTGATGATTACTTATGGAGAGATTAAATCCAAGTTAGGAAGTGAACTAGAGATTTATG
CTCAAGAGAGTTGGACTCAGTTTTTCAGCCAACTTCATCAAGCAACTCAGTTTATTCAACCGATTATCTTTTTAGTGATT
GCTCTGACGATTGTCATGATTTATGCAGCAATTTTATTACCAATTTATCAAAATATGGGAGGCGTTTTATAA

Domains

Predicted by InterProScan.

• Type II secretion system (T2SS), protein F (T2SSF) (28-146)

• Type II secretion system (T2SS), protein F (T2SSF) (214-334)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGB	Streptococcus mutans UA140	53.392	98.834	0.528
comGB	Streptococcus mutans UA159	53.392	98.834	0.528
comGB	Streptococcus gordonii str. Challis substr. CH1	48.673	98.834	0.481
comGB/cglB	Streptococcus mitis NCTC 12261	45.97	97.668	0.449
comGB/cglB	Streptococcus mitis SK321	45.345	97.085	0.44
comGB/cglB	Streptococcus pneumoniae Rx1	43.844	97.085	0.426
comGB/cglB	Streptococcus pneumoniae D39	43.844	97.085	0.426
comGB/cglB	Streptococcus pneumoniae R6	43.844	97.085	0.426
comGB/cglB	Streptococcus pneumoniae TIGR4	43.844	97.085	0.426
comGB	Lactococcus lactis subsp. cremoris KW2	42.478	98.834	0.42