Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   NJN40_RS10125 Genome accession   NZ_CP102859
Coordinates   2095474..2096715 (-) Length   413 a.a.
NCBI ID   WP_003569520.1    Uniprot ID   A0A829GUR5
Organism   Lacticaseibacillus paracasei strain DM001     
Function   facilitate localization of RecA (predicted from homology)   
Homologous recombination

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
ICE 2090456..2122364 2095474..2096715 within 0


Gene organization within MGE regions


Location: 2090456..2122364
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NJN40_RS10105 (NJN40_10105) - 2090456..2091718 (-) 1263 WP_003569529.1 helicase-related protein -
  NJN40_RS10110 (NJN40_10110) - 2091746..2092396 (+) 651 WP_003569527.1 YigZ family protein -
  NJN40_RS10115 (NJN40_10115) rny 2092490..2094061 (-) 1572 WP_003657913.1 ribonuclease Y -
  NJN40_RS10120 (NJN40_10120) recA 2094356..2095417 (-) 1062 WP_003587498.1 recombinase RecA Machinery gene
  NJN40_RS10125 (NJN40_10125) cinA 2095474..2096715 (-) 1242 WP_003569520.1 competence/damage-inducible protein A Machinery gene
  NJN40_RS10130 (NJN40_10130) pgsA 2097132..2097725 (-) 594 WP_003569518.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  NJN40_RS10135 (NJN40_10135) - 2097722..2098651 (-) 930 WP_253613657.1 helix-turn-helix domain-containing protein -
  NJN40_RS10140 (NJN40_10140) ymfI 2098738..2099466 (-) 729 WP_003569514.1 elongation factor P 5-aminopentanone reductase -
  NJN40_RS10145 (NJN40_10145) yfmH 2099466..2100758 (-) 1293 WP_003569512.1 EF-P 5-aminopentanol modification-associated protein YfmH -
  NJN40_RS10150 (NJN40_10150) yfmF 2100755..2102017 (-) 1263 WP_003569510.1 EF-P 5-aminopentanol modification-associated protein YfmF -
  NJN40_RS10155 (NJN40_10155) - 2102026..2104347 (-) 2322 WP_003569507.1 DNA translocase FtsK -
  NJN40_RS10160 (NJN40_10160) - 2104520..2104930 (-) 411 WP_003564159.1 DUF1149 family protein -
  NJN40_RS10165 (NJN40_10165) trmL 2105057..2105566 (-) 510 WP_003569505.1 tRNA (uridine(34)/cytosine(34)/5- carboxymethylaminomethyluridine(34)-2'-O)- methyltransferase TrmL -
  NJN40_RS10170 (NJN40_10170) - 2105821..2106663 (-) 843 WP_003569501.1 methyltransferase domain-containing protein -
  NJN40_RS10175 (NJN40_10175) - 2106729..2107676 (+) 948 WP_003564155.1 magnesium transporter CorA family protein -
  NJN40_RS10180 (NJN40_10180) - 2107916..2108893 (+) 978 WP_253613898.1 GMP reductase -
  NJN40_RS10185 (NJN40_10185) rpsN 2109021..2109290 (+) 270 WP_003564153.1 30S ribosomal protein S14 -
  NJN40_RS10190 (NJN40_10190) - 2109402..2109779 (-) 378 WP_253613658.1 PTS glucitol/sorbitol transporter subunit IIA -
  NJN40_RS10195 (NJN40_10195) - 2110051..2111091 (+) 1041 WP_016375060.1 lactonase family protein -
  NJN40_RS10200 (NJN40_10200) - 2111294..2112112 (+) 819 WP_016373579.1 undecaprenyl-diphosphate phosphatase -
  NJN40_RS10205 (NJN40_10205) - 2112134..2112769 (+) 636 WP_003569480.1 copper homeostasis protein CutC -
  NJN40_RS10210 (NJN40_10210) - 2112926..2113984 (+) 1059 WP_253613659.1 FAD:protein FMN transferase -
  NJN40_RS10215 (NJN40_10215) - 2114093..2114995 (-) 903 WP_128537623.1 RluA family pseudouridine synthase -
  NJN40_RS10220 (NJN40_10220) - 2114995..2115792 (-) 798 WP_003564146.1 NAD kinase -
  NJN40_RS10225 (NJN40_10225) - 2115794..2116465 (-) 672 WP_003564145.1 GTP pyrophosphokinase family protein -
  NJN40_RS10230 (NJN40_10230) - 2116659..2117252 (+) 594 WP_076653169.1 CYTH domain-containing protein -
  NJN40_RS10235 (NJN40_10235) - 2117322..2117957 (+) 636 WP_003564143.1 DsbA family protein -
  NJN40_RS10240 (NJN40_10240) - 2118147..2119202 (-) 1056 WP_253613660.1 competence protein CoiA -
  NJN40_RS10245 (NJN40_10245) - 2119312..2120655 (-) 1344 WP_003569470.1 PFL family protein -
  NJN40_RS10250 (NJN40_10250) - 2120704..2120970 (-) 267 WP_003564140.1 ACT domain-containing protein -
  NJN40_RS10255 (NJN40_10255) - 2121161..2121334 (+) 174 Protein_2026 phosphohydrolase -
  NJN40_RS10260 (NJN40_10260) - 2121444..2122364 (+) 921 WP_003574021.1 IS30 family transposase -

Sequence

Protein


Download         Length: 413 a.a.        Molecular weight: 44239.57 Da        Isoelectric Point: 6.1814

>NTDB_id=719344 NJN40_RS10125 WP_003569520.1 2095474..2096715(-) (cinA) [Lacticaseibacillus paracasei strain DM001]
MQAEIIAVGTEILMGQITNTNGAYMAKQLTALGIDSYHQQVVGDNGPRLEEAIKLAESRSNLVILIGGLGPTPDDLTKQT
LAAHLNRKLVEDPAAMAKLQARAKQQQRPMTPNNQLQAMYPEGADILVNRVGLAVGAWIVNGQHTYVLLPGPPKEFVPMV
DHELLPRLAKWSGHAEVMVSRVLRFFGIGESQLVTDLDDLIANQTDPTIATYIKDHEVTVRVTASGANEKDADAKLEPMV
GAIMDRDGQYFYGYGDDNSLAKELVKTLAANDMQITAAESLTAGAFQAALGDVPGVSTYFKGGFVTYSLATKAAFLAIDA
RELAAHGVVSAFTAKAMAEHARRKAAADISVSFTGVAGPDTLEGQPAGTVWIGLARRGQLPEAHVYHFPGGRNDVRQRAV
MTGMMLALRALQA

Nucleotide


Download         Length: 1242 bp        

>NTDB_id=719344 NJN40_RS10125 WP_003569520.1 2095474..2096715(-) (cinA) [Lacticaseibacillus paracasei strain DM001]
ATGCAAGCAGAGATTATTGCTGTCGGGACAGAGATCCTGATGGGACAGATTACTAACACAAATGGTGCCTATATGGCTAA
GCAACTGACAGCACTGGGTATTGATAGCTACCATCAACAGGTGGTGGGAGACAACGGTCCGCGACTTGAGGAGGCCATTA
AGTTGGCGGAAAGTCGCAGTAATTTAGTTATTTTGATTGGCGGGTTAGGACCGACACCAGATGATCTGACCAAGCAAACA
TTGGCAGCGCACTTGAACCGCAAATTGGTTGAAGATCCTGCCGCTATGGCTAAATTACAGGCGCGCGCCAAGCAACAGCA
GCGGCCAATGACGCCTAATAATCAATTACAGGCCATGTATCCGGAAGGCGCCGATATTTTGGTCAATCGGGTTGGCTTAG
CGGTTGGTGCGTGGATCGTCAATGGGCAGCACACCTATGTCTTATTGCCGGGACCACCCAAGGAATTCGTTCCGATGGTT
GATCATGAACTGCTGCCGCGGCTAGCAAAATGGAGCGGCCACGCGGAAGTTATGGTCAGCCGGGTCTTACGTTTCTTTGG
CATTGGCGAATCGCAACTAGTGACAGATCTGGACGACTTGATTGCCAACCAAACCGATCCGACCATTGCAACTTATATCA
AGGATCATGAGGTGACGGTGCGCGTCACTGCCAGTGGCGCTAACGAAAAAGACGCTGATGCAAAGTTAGAACCAATGGTC
GGTGCCATCATGGATCGTGATGGTCAATATTTTTACGGCTACGGTGACGACAATAGTTTGGCAAAAGAGCTTGTGAAGAC
GCTTGCGGCAAATGATATGCAAATTACTGCAGCTGAGAGTTTGACTGCCGGCGCATTTCAAGCAGCGTTAGGCGATGTGC
CGGGGGTATCCACTTATTTTAAGGGAGGTTTTGTCACTTACTCACTTGCAACAAAGGCCGCTTTTTTGGCAATTGATGCT
CGCGAATTAGCGGCACACGGAGTTGTCAGCGCATTTACAGCCAAGGCGATGGCTGAACATGCTCGGCGTAAGGCAGCGGC
GGATATAAGTGTCAGCTTTACCGGCGTTGCCGGTCCAGACACGCTGGAAGGACAGCCTGCTGGTACGGTTTGGATCGGTT
TAGCGCGGCGCGGCCAACTGCCTGAAGCACATGTTTACCATTTTCCTGGCGGTCGCAATGATGTTCGGCAGCGTGCTGTG
ATGACTGGTATGATGCTTGCATTAAGGGCGCTGCAGGCCTAA

Domains

Predicted by InterproScan.

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)

Damage-inducible protein CinA KH domain (CinA_KH)

(180-253)

Competence-damaged protein (CinA)

(258-410)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A829GUR5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mitis NCTC 12261

51.651

100

0.53
  cinA Streptococcus mitis SK321

51.537

100

0.528
  cinA Streptococcus pneumoniae TIGR4

51.415

100

0.528
  cinA Streptococcus mutans UA159

52.174

100

0.523
  cinA Streptococcus pneumoniae Rx1

50.948

100

0.521
  cinA Streptococcus pneumoniae R6

50.948

100

0.521
  cinA Streptococcus pneumoniae D39

50.711

100

0.518
  cinA Bacillus subtilis subsp. subtilis str. 168

45.012

99.516

0.448
  cinA Streptococcus suis isolate S10

42.328

91.525

0.387