Detailed information NTG0718679

Bioinformatically predicted

Overview

• Name: comE/blpR
• Type: Regulator
• Locus tag: NWE22_RS00905
• Genome accession: NZ_CP102747
• Coordinates: 166998..167735 (+)
• Length: 245 a.a.
• NCBI ID: WP_171989915.1
• Uniprot ID: -
• Organism: Streptococcus parasuis strain SFJ45
• Function: activate transcription of early competence genes; regulation of comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 161998..172735

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NWE22_RS00885 (NWE22_00885)	-	162015..162785 (+)	771	WP_174846587.1	hypothetical protein	-
NWE22_RS00890 (NWE22_00890)	-	162788..164503 (+)	1716	WP_174846586.1	ABC transporter ATP-binding protein	-
NWE22_RS00895 (NWE22_00895)	-	164766..166103 (-)	1338	Protein_154	ISL3 family transposase	-
NWE22_RS00900 (NWE22_00900)	-	166471..166854 (-)	384	WP_174846550.1	hypothetical protein	-
NWE22_RS00905 (NWE22_00905)	comE/blpR	166998..167735 (+)	738	WP_171989915.1	response regulator transcription factor	Regulator
NWE22_RS00910 (NWE22_00910)	-	167739..169088 (+)	1350	WP_171989914.1	GHKL domain-containing protein	-
NWE22_RS00915 (NWE22_00915)	-	169042..169680 (-)	639	WP_174846551.1	cysteine hydrolase family protein	-
NWE22_RS00920 (NWE22_00920)	-	170277..172010 (+)	1734	WP_174846552.1	hypothetical protein	-

Sequence

Protein

• Length: 245 a.a.
• Molecular weight: 28407.32 Da
• Isoelectric Point: 5.7912

>NTDB_id=718679 NWE22_RS00905 WP_171989915.1 166998..167735(+) (comE/blpR) [Streptococcus parasuis strain SFJ45]
MLNIFILEDDYLQQTRLENVIKQSVATNNLKYRHLEIYGKPHQLLETISEKGNHQLFFLDIEIRGEEQKGMEIAREIRLK
DPNAVIVFVSTHSEFMPVTYKYRVSALDFIDKGLPEEEFQDAVTSVLVHAYENVGRTVGEDAFVFKSEHSHVQVPFSDIL
FFETSTTVHKVILYTKTGQLEFYGKVSEIAKSDERLYQSHRAYVVNPQNIVRIDRANHMVYFEGDESCFVSKLKLKGLIE
KVENP

Nucleotide

• Length: 738 bp

>NTDB_id=718679 NWE22_RS00905 WP_171989915.1 166998..167735(+) (comE/blpR) [Streptococcus parasuis strain SFJ45]
ATGTTAAATATTTTTATATTAGAGGATGACTATCTGCAACAAACTCGTTTAGAAAATGTCATTAAGCAGAGTGTAGCCAC
AAATAATTTGAAATACAGGCATCTAGAGATCTATGGGAAGCCCCACCAATTACTAGAGACTATTTCCGAAAAAGGAAACC
ATCAGCTATTTTTCCTGGATATAGAGATTAGGGGAGAAGAGCAAAAAGGAATGGAGATTGCGCGTGAAATCCGTTTAAAA
GACCCCAATGCGGTCATTGTTTTTGTGTCCACTCATTCGGAATTCATGCCAGTAACCTATAAATATCGCGTGTCAGCGCT
GGACTTCATTGATAAAGGATTGCCTGAGGAGGAGTTTCAGGATGCTGTTACTTCGGTTTTGGTTCATGCCTATGAAAATG
TGGGGCGCACAGTCGGAGAAGATGCTTTTGTCTTTAAAAGCGAGCATTCACATGTTCAGGTTCCTTTTTCAGATATCCTC
TTCTTTGAGACATCTACAACTGTCCATAAGGTCATTCTTTATACCAAGACAGGACAACTGGAATTCTATGGCAAGGTATC
AGAAATTGCCAAATCTGATGAACGGCTCTATCAAAGCCATCGTGCTTATGTCGTGAATCCCCAAAATATTGTACGCATTG
ATCGTGCCAACCACATGGTTTATTTTGAAGGTGATGAATCTTGTTTTGTCTCCAAGTTGAAATTAAAGGGCCTGATTGAA
AAAGTGGAGAATCCGTAA

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (4-123)

• LytTr DNA-binding domain (LytTR) (152-241)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comE/blpR	Streptococcus mutans UA159	53.556	97.551	0.522
comE/comE1	Streptococcus equinus JB1	45.041	98.776	0.445
comE/comE2	Streptococcus equinus JB1	40.984	99.592	0.408
comE/comE2	Streptococcus gordonii strain NCTC7865	36.885	99.592	0.367
comE/comE1	Streptococcus gordonii str. Challis substr. CH1	36.885	99.592	0.367
comE	Streptococcus mitis SK321	35.458	100	0.363
comE	Streptococcus pneumoniae Rx1	35.458	100	0.363
comE	Streptococcus pneumoniae D39	35.458	100	0.363
comE	Streptococcus pneumoniae R6	35.458	100	0.363
comE	Streptococcus pneumoniae TIGR4	35.458	100	0.363
comE	Streptococcus mitis NCTC 12261	35.458	100	0.363