Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   NPS17_RS09720 Genome accession   NZ_CP101985
Coordinates   2039634..2040890 (-) Length   418 a.a.
NCBI ID   WP_002266115.1    Uniprot ID   -
Organism   Streptococcus mutans strain COCC33-14R     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 2034634..2045890
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NPS17_RS09675 (NPS17_09675) - 2034826..2035125 (-) 300 WP_002262384.1 DUF1292 domain-containing protein -
  NPS17_RS09680 (NPS17_09680) ruvX 2035206..2035625 (-) 420 WP_002262385.1 Holliday junction resolvase RuvX -
  NPS17_RS09685 (NPS17_09685) - 2035622..2035891 (-) 270 WP_002262386.1 IreB family regulatory phosphoprotein -
  NPS17_RS09690 (NPS17_09690) brsR 2036059..2036493 (+) 435 WP_002266979.1 bacteriocin genes transcriptional regulator BrsR Regulator
  NPS17_RS09695 (NPS17_09695) brsM 2036506..2036952 (+) 447 WP_002284633.1 bacteriocin genes regulator BrsM Regulator
  NPS17_RS09700 (NPS17_09700) - 2036943..2037142 (-) 200 Protein_1865 hypothetical protein -
  NPS17_RS09705 (NPS17_09705) - 2037283..2037708 (-) 426 WP_002266116.1 hypothetical protein -
  NPS17_RS09710 (NPS17_09710) spx 2037960..2038358 (-) 399 WP_002262391.1 transcriptional regulator Spx -
  NPS17_RS09715 (NPS17_09715) recA 2038443..2039594 (-) 1152 WP_002262392.1 recombinase RecA Machinery gene
  NPS17_RS09720 (NPS17_09720) cinA 2039634..2040890 (-) 1257 WP_002266115.1 competence/damage-inducible protein A Machinery gene
  NPS17_RS09725 (NPS17_09725) - 2041039..2041599 (-) 561 WP_258969005.1 DNA-3-methyladenine glycosylase I -
  NPS17_RS09730 (NPS17_09730) ruvA 2041681..2042274 (-) 594 WP_002266975.1 Holliday junction branch migration protein RuvA -
  NPS17_RS09735 (NPS17_09735) mutL 2042458..2044413 (-) 1956 WP_258969006.1 DNA mismatch repair endonuclease MutL -
  NPS17_RS09740 (NPS17_09740) - 2044638..2044916 (+) 279 Protein_1873 transposase -

Sequence

Protein


Download         Length: 418 a.a.        Molecular weight: 45718.51 Da        Isoelectric Point: 6.2714

>NTDB_id=713618 NPS17_RS09720 WP_002266115.1 2039634..2040890(-) (cinA) [Streptococcus mutans strain COCC33-14R]
MKSEIIAVGTEILTGQIVNTNSQFLSEKFAELGIDVYFQTAVGDNEERLLSVLKIAKERSDLIVLCGGLGPTEDDLTKQT
LAKFLKRELVFDKTAQERLDEFFASRPTSMRTPNNECQAQIIAGSQPLSNKTGLAVGGLLEADGVTYVVLPGPPSELKPM
VNKELLPYLSKTSEKLYSRVLRFFGIGESHLVTLLHDLIAEQTDPTIAPYAKTGEVTIRLSTKAHRQKEADSKLDKLEKK
IITIDNLADYFYGYGEENSLPQVVFDLLKEKGKTITAAESLTAGLFQARLADFAGASDIFKGGFITYSIEEKARMLGIPF
EDLQLHGVVSAFTAEKMAERSRQLTQADLAVSLTGVAGPDSLEGQPAGTVFIGLSSSKRTMAIKVLIGGRSRSDVRYIAV
LHAFNLVRQTLLSHKNLV

Nucleotide


Download         Length: 1257 bp        

>NTDB_id=713618 NPS17_RS09720 WP_002266115.1 2039634..2040890(-) (cinA) [Streptococcus mutans strain COCC33-14R]
ATGAAATCTGAGATCATTGCTGTTGGAACAGAAATTTTAACAGGACAAATTGTTAATACTAATAGTCAATTTTTATCAGA
AAAATTCGCAGAATTAGGAATTGATGTTTATTTTCAAACAGCAGTTGGTGATAATGAAGAACGCCTTTTATCTGTTTTGA
AAATTGCAAAGGAACGTAGTGATTTAATCGTACTTTGTGGTGGTTTGGGACCAACAGAAGATGATTTAACAAAACAAACC
CTAGCAAAATTTTTGAAAAGAGAATTGGTATTTGATAAAACAGCTCAAGAACGTCTAGATGAATTTTTTGCATCACGTCC
AACATCTATGCGCACACCAAATAATGAATGTCAGGCGCAGATTATAGCAGGAAGTCAGCCTTTATCTAATAAAACAGGCT
TAGCAGTTGGGGGGCTTTTGGAGGCAGATGGAGTGACTTATGTTGTATTACCTGGTCCGCCTAGCGAATTGAAGCCTATG
GTTAACAAAGAGTTACTCCCTTATTTATCAAAAACTTCTGAGAAGCTTTATTCTCGTGTGTTACGCTTTTTTGGTATTGG
TGAGAGTCATCTAGTGACCTTGTTGCATGACTTAATAGCGGAGCAAACAGATCCCACAATTGCTCCTTATGCTAAGACAG
GCGAGGTAACAATACGTTTATCAACAAAAGCCCATAGGCAGAAAGAAGCAGATAGTAAGTTAGATAAGTTGGAAAAGAAA
ATTATAACTATTGATAACTTGGCTGATTATTTTTATGGTTATGGTGAAGAAAATTCATTACCACAGGTTGTATTTGATCT
GCTTAAGGAAAAGGGTAAAACGATTACAGCAGCTGAAAGTTTAACAGCAGGCCTTTTTCAGGCAAGATTAGCAGATTTTG
CAGGAGCATCTGATATCTTTAAGGGAGGTTTTATAACTTACAGTATAGAAGAGAAGGCTAGAATGCTAGGTATTCCCTTT
GAAGATCTCCAACTTCATGGGGTTGTTAGTGCTTTTACTGCTGAAAAGATGGCAGAGCGCTCCCGCCAGCTGACTCAAGC
AGATTTGGCTGTTTCTTTAACAGGAGTTGCAGGTCCGGATAGCTTAGAAGGTCAGCCGGCAGGGACAGTTTTTATCGGTT
TGTCAAGTTCCAAAAGAACAATGGCAATCAAAGTGTTAATTGGCGGACGCAGTCGGTCTGATGTGCGTTATATCGCTGTT
TTACATGCTTTTAATTTAGTACGTCAAACTTTATTATCTCATAAAAATTTAGTATAA

Domains

Predicted by InterproScan.

Damage-inducible protein CinA KH domain (CinA_KH)

(178-253)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-170)

Competence-damaged protein (CinA)

(259-411)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mutans UA159

99.761

100

0.998
  cinA Streptococcus mitis SK321

72.249

100

0.722
  cinA Streptococcus mitis NCTC 12261

71.77

100

0.718
  cinA Streptococcus pneumoniae TIGR4

70.574

100

0.706
  cinA Streptococcus pneumoniae Rx1

70.335

100

0.703
  cinA Streptococcus pneumoniae R6

70.335

100

0.703
  cinA Streptococcus pneumoniae D39

70.096

100

0.701
  cinA Streptococcus suis isolate S10

55.474

98.325

0.545
  cinA Bacillus subtilis subsp. subtilis str. 168

45.763

98.804

0.452