Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   NMH04_RS08705 Genome accession   NZ_CP101609
Coordinates   1717351..1718601 (+) Length   416 a.a.
NCBI ID   WP_045034294.1    Uniprot ID   -
Organism   Bacillus altitudinis strain 47     
Function   unknown (predicted from homology)   
Unclear

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
ICE 1698358..1740332 1717351..1718601 within 0


Gene organization within MGE regions


Location: 1698358..1740332
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NMH04_RS08635 (NMH04_08610) - 1698912..1699148 (+) 237 WP_008344712.1 YlzJ-like family protein -
  NMH04_RS08640 (NMH04_08615) - 1699259..1701634 (+) 2376 WP_173408012.1 DNA translocase FtsK -
  NMH04_RS08645 (NMH04_08620) - 1701799..1702524 (+) 726 WP_008344706.1 GntR family transcriptional regulator -
  NMH04_RS08650 (NMH04_08625) - 1702625..1703857 (+) 1233 WP_173408013.1 MFS transporter -
  NMH04_RS08655 (NMH04_08630) - 1704177..1707293 (+) 3117 WP_173408014.1 MMPL family transporter -
  NMH04_RS08660 (NMH04_08635) - 1707439..1708719 (+) 1281 WP_056704743.1 pitrilysin family protein -
  NMH04_RS08665 (NMH04_08640) - 1708716..1710008 (+) 1293 WP_041507268.1 pitrilysin family protein -
  NMH04_RS08670 (NMH04_08645) - 1710160..1710636 (+) 477 WP_024720380.1 MarR family winged helix-turn-helix transcriptional regulator -
  NMH04_RS08675 (NMH04_08650) - 1710614..1713733 (+) 3120 WP_041507267.1 MMPL family transporter -
  NMH04_RS08680 (NMH04_08655) - 1713763..1714491 (+) 729 WP_024720382.1 SDR family oxidoreductase -
  NMH04_RS08685 (NMH04_08660) - 1714564..1714821 (+) 258 WP_003211590.1 DUF3243 domain-containing protein -
  NMH04_RS08690 (NMH04_08665) - 1714953..1715744 (+) 792 WP_039166619.1 DUF3388 domain-containing protein -
  NMH04_RS08695 (NMH04_08670) - 1715768..1716679 (+) 912 WP_041507265.1 helix-turn-helix domain-containing protein -
  NMH04_RS08700 (NMH04_08675) pgsA 1716753..1717334 (+) 582 WP_008344688.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  NMH04_RS08705 (NMH04_08680) cinA 1717351..1718601 (+) 1251 WP_045034294.1 competence/damage-inducible protein A Machinery gene
  NMH04_RS08710 (NMH04_08685) recA 1718780..1719823 (+) 1044 WP_007499478.1 recombinase RecA Machinery gene
  NMH04_RS08715 (NMH04_08690) rny 1720124..1721686 (+) 1563 WP_003211958.1 ribonuclease Y -
  NMH04_RS08720 (NMH04_08695) - 1721776..1722570 (+) 795 WP_019744184.1 TIGR00282 family metallophosphoesterase -
  NMH04_RS08725 (NMH04_08700) spoVS 1722773..1723033 (+) 261 WP_003211281.1 stage V sporulation protein SpoVS -
  NMH04_RS08730 (NMH04_08705) - 1723237..1726281 (+) 3045 WP_041507263.1 efflux RND transporter permease subunit -
  NMH04_RS08735 (NMH04_08710) tdh 1726458..1727522 (+) 1065 WP_041507262.1 L-threonine 3-dehydrogenase -
  NMH04_RS08740 (NMH04_08715) - 1727519..1728700 (+) 1182 WP_007499472.1 glycine C-acetyltransferase -
  NMH04_RS08745 (NMH04_08720) miaB 1728859..1730385 (+) 1527 WP_007499471.1 tRNA (N6-isopentenyl adenosine(37)-C2)-methylthiotransferase MiaB -
  NMH04_RS08750 (NMH04_08725) - 1730387..1730821 (+) 435 WP_008344661.1 RicAFT regulatory complex protein RicA family protein -
  NMH04_RS08755 (NMH04_08730) cotE 1731070..1731615 (+) 546 WP_163116186.1 outer spore coat protein CotE -
  NMH04_RS08760 (NMH04_08735) mutS 1731740..1734316 (+) 2577 WP_041507261.1 DNA mismatch repair protein MutS -
  NMH04_RS08765 (NMH04_08740) mutL 1734339..1736240 (+) 1902 WP_100325020.1 DNA mismatch repair endonuclease MutL -
  NMH04_RS08770 (NMH04_08745) - 1736291..1737403 (-) 1113 WP_255817013.1 site-specific integrase -
  NMH04_RS08775 (NMH04_08750) - 1737439..1737882 (-) 444 WP_255817014.1 ImmA/IrrE family metallo-endopeptidase -
  NMH04_RS08780 (NMH04_08755) - 1737901..1738320 (-) 420 WP_159159639.1 helix-turn-helix domain-containing protein -
  NMH04_RS08785 (NMH04_08760) - 1738624..1738827 (+) 204 WP_216942344.1 helix-turn-helix domain-containing protein -
  NMH04_RS08790 (NMH04_08765) - 1738827..1739096 (+) 270 WP_216942346.1 group-specific protein -
  NMH04_RS08795 (NMH04_08770) - 1739249..1739898 (+) 650 Protein_1684 Rha family transcriptional regulator -
  NMH04_RS08805 (NMH04_08780) - 1739959..1740309 (+) 351 WP_216942350.1 hypothetical protein -

Sequence

Protein


Download         Length: 416 a.a.        Molecular weight: 45585.73 Da        Isoelectric Point: 4.9193

>NTDB_id=710790 NMH04_RS08705 WP_045034294.1 1717351..1718601(+) (cinA) [Bacillus altitudinis strain 47]
MKSERKAEIIAVGSELLLGQITNTNAQFISKQLAEIGVNVYYHTAVGDNPERLKKAIQVAQERSNFIIFSGGLGPTKDDL
TKETIASTLGKELVLNEEAFESIQEYFRKTGRDMSPNNRKQALVLEGSDVLVNRFGMAPGMFIQEGDTFYILLPGPPSEL
HPMFENEAKPLISEKLGLKEKIVSVVLRFFGIGESQLETDLEDLIDAQTNPTIAPLAADGEVTLRLTAKHEDEKETERLL
KETEAQILERVGEYFYGYGNTSLAFEASKALHEHGKTVAAAESLTGGMFSEWLTDLEGASSILNGSVVCYTNQVKQQVLG
CREETLSSHGAVSKECALELAEGVRKLTGSDIGISFTGVAGPEPHEGQPVGKVFIGLSTKDQTDVFEWMFTGSRSGIRKR
AVKYGLHHLLKLLKDS

Nucleotide


Download         Length: 1251 bp        

>NTDB_id=710790 NMH04_RS08705 WP_045034294.1 1717351..1718601(+) (cinA) [Bacillus altitudinis strain 47]
TTGAAGTCAGAGAGAAAAGCAGAAATTATTGCAGTCGGTTCCGAACTTTTGCTAGGGCAAATTACGAATACGAATGCACA
ATTCATCAGCAAACAACTAGCTGAAATTGGTGTGAATGTTTATTACCACACAGCAGTTGGTGACAATCCAGAGCGTTTAA
AAAAGGCCATTCAAGTGGCACAGGAAAGATCGAATTTTATTATCTTCTCAGGTGGTCTTGGACCAACGAAAGACGATTTA
ACAAAAGAAACCATTGCGAGTACGCTCGGTAAAGAGCTTGTGCTAAATGAAGAAGCATTTGAGTCTATTCAAGAATACTT
CCGTAAAACCGGACGCGATATGTCGCCGAACAACCGTAAACAGGCGCTCGTTCTAGAGGGATCTGATGTGCTCGTAAACC
GTTTCGGAATGGCACCTGGTATGTTTATACAAGAGGGAGATACGTTTTACATTCTGCTCCCTGGACCGCCAAGTGAATTG
CACCCGATGTTTGAAAACGAAGCGAAGCCGCTTATTTCTGAAAAACTCGGCCTAAAGGAAAAAATCGTGTCTGTTGTCTT
GCGTTTCTTTGGCATCGGTGAATCTCAGCTGGAAACAGATCTTGAAGATTTAATTGATGCACAGACCAATCCAACGATTG
CACCGCTTGCAGCTGACGGGGAAGTGACGCTAAGGCTGACAGCCAAGCATGAGGATGAAAAAGAAACAGAGCGTCTGTTA
AAAGAAACAGAAGCACAAATTTTAGAACGGGTCGGCGAGTACTTCTACGGATATGGTAATACATCTCTTGCCTTTGAAGC
TTCAAAGGCCTTGCATGAACACGGGAAAACAGTAGCAGCGGCTGAAAGCCTGACTGGTGGTATGTTTTCAGAGTGGCTGA
CAGATCTCGAAGGGGCATCATCCATTTTAAACGGCAGTGTGGTTTGTTACACAAATCAAGTCAAGCAGCAAGTGCTGGGC
TGCCGTGAAGAAACATTGTCTTCTCATGGTGCTGTCAGCAAAGAGTGTGCGTTAGAGCTCGCAGAAGGCGTTAGAAAACT
GACGGGAAGCGATATCGGTATTAGCTTTACAGGTGTGGCAGGTCCTGAACCACACGAAGGACAGCCGGTTGGAAAAGTAT
TTATCGGGCTATCGACAAAAGACCAGACAGACGTGTTTGAATGGATGTTTACTGGCAGTCGATCAGGCATTCGCAAGCGT
GCTGTGAAATATGGTTTGCACCACCTTCTCAAATTATTAAAAGATAGTTAA

Domains

Predicted by InterproScan.

Competence-damaged protein (CinA)

(262-412)

Probable molybdopterin binding domain (MoCF_biosynth)

(9-172)

Damage-inducible protein CinA KH domain (CinA_KH)

(186-257)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Bacillus subtilis subsp. subtilis str. 168

74.638

99.519

0.743
  cinA Streptococcus mitis SK321

47.981

100

0.486
  cinA Streptococcus mitis NCTC 12261

47.743

100

0.483
  cinA Streptococcus pneumoniae TIGR4

47.743

100

0.483
  cinA Streptococcus pneumoniae Rx1

47.506

100

0.481
  cinA Streptococcus pneumoniae R6

47.506

100

0.481
  cinA Streptococcus pneumoniae D39

47.268

100

0.478
  cinA Streptococcus mutans UA159

48.157

97.837

0.471
  cinA Streptococcus suis isolate S10

43.122

90.865

0.392