Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   NLY35_RS00385 Genome accession   NZ_CP100418
Coordinates   67312..68493 (+) Length   393 a.a.
NCBI ID   WP_024403265.1    Uniprot ID   -
Organism   Streptococcus suis strain STC104     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 62312..73493
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NLY35_RS00370 (NLY35_00370) mutL 63510..65447 (+) 1938 WP_172060540.1 DNA mismatch repair endonuclease MutL -
  NLY35_RS00375 (NLY35_00375) ruvA 65486..66076 (+) 591 WP_024403269.1 Holliday junction branch migration protein RuvA -
  NLY35_RS00380 (NLY35_00380) - 66706..67275 (+) 570 WP_024417855.1 DNA-3-methyladenine glycosylase I -
  NLY35_RS00385 (NLY35_00385) cinA 67312..68493 (+) 1182 WP_024403265.1 competence/damage-inducible protein A Machinery gene
  NLY35_RS00390 (NLY35_00390) recA 68545..69696 (+) 1152 WP_024387809.1 recombinase RecA Machinery gene
  NLY35_RS00395 (NLY35_00395) spx 69932..70330 (+) 399 WP_002939362.1 transcriptional regulator Spx -
  NLY35_RS00400 (NLY35_00400) - 70430..70696 (+) 267 WP_024403264.1 IreB family regulatory phosphoprotein -
  NLY35_RS00405 (NLY35_00405) ruvX 70696..71115 (+) 420 WP_002939356.1 Holliday junction resolvase RuvX -
  NLY35_RS00410 (NLY35_00410) - 71127..71447 (+) 321 WP_002939343.1 DUF1292 domain-containing protein -
  NLY35_RS00415 (NLY35_00415) - 71605..72173 (+) 569 Protein_62 nucleotidyltransferase family protein -
  NLY35_RS00420 (NLY35_00420) comX/sigX 72247..72513 (+) 267 WP_204101662.1 transcriptional regulator Regulator
  NLY35_RS00425 (NLY35_00425) rpsJ 72836..73144 (+) 309 WP_014735259.1 30S ribosomal protein S10 -

Sequence

Protein


Download         Length: 393 a.a.        Molecular weight: 43036.76 Da        Isoelectric Point: 4.2199

>NTDB_id=704945 NLY35_RS00385 WP_024403265.1 67312..68493(+) (cinA) [Streptococcus suis strain STC104]
MKAELIAVGTEILTGQIVNTNAQFLSEKCAELGIDVYFHTAVGDNENRLLSVLEVASQRSDLVFLCGGLGPTEDDLTKQT
LATFLGRNLVFDELAMAKLDRFFASRPGRVRTPNNERQAQIVEGSQALQNPAGLAVGGMIEQDGVTYIVLPGPPSELKAM
FSESLLPLLSQSQQQLYSRVLRFFGIGESQLVTVLSDLIEQQTDPTLAPYAKIGEVTLRLSTKANSQEEADLRLNQLEEE
ILQHDKLADYFYAYGEENSLVQTVAERLVEKNKSIAIVEQGTGGLLQAELSLALADQPYFSGGKVIGQLGTESGWLSEEA
DCIRQELQADLGLAVSVLIKPESTEDNVLAKVYLTLATPSGISQKEIDLGGYSWQYLRQLACLQAWDFVRNTL

Nucleotide


Download         Length: 1182 bp        

>NTDB_id=704945 NLY35_RS00385 WP_024403265.1 67312..68493(+) (cinA) [Streptococcus suis strain STC104]
ATGAAAGCAGAACTAATCGCCGTTGGGACGGAGATTTTGACAGGCCAAATCGTTAATACCAATGCTCAGTTCCTTTCGGA
GAAATGTGCAGAGCTGGGAATTGATGTTTATTTCCACACAGCTGTTGGAGATAATGAAAACAGGCTTCTGTCTGTACTGG
AAGTTGCCAGTCAGCGGAGCGACTTGGTCTTTCTCTGTGGAGGACTTGGTCCAACTGAGGATGACTTGACCAAGCAGACC
CTGGCGACCTTCTTAGGTAGAAACCTTGTGTTTGATGAGTTGGCTATGGCAAAATTAGACCGTTTCTTTGCCAGTCGACC
AGGTCGTGTTCGCACACCTAATAATGAGCGTCAAGCACAGATTGTAGAGGGAAGTCAGGCGCTACAGAATCCAGCTGGTT
TAGCTGTTGGTGGTATGATTGAGCAAGATGGTGTAACCTATATTGTTTTGCCTGGCCCACCAAGTGAGCTCAAGGCCATG
TTTTCTGAGAGTCTCTTACCTTTACTGTCCCAATCTCAGCAGCAACTTTATTCGCGTGTCCTACGCTTTTTTGGAATTGG
CGAAAGCCAGTTGGTGACTGTTTTGTCGGATTTGATTGAACAGCAGACAGATCCTACCTTAGCCCCCTATGCCAAGATTG
GTGAAGTGACCTTACGTTTATCTACTAAGGCAAATAGTCAAGAAGAAGCAGATTTGCGTCTGAATCAGTTGGAAGAAGAA
ATCTTACAACATGACAAACTGGCAGACTATTTCTATGCCTACGGTGAGGAAAATAGTCTGGTACAGACAGTAGCAGAGCG
ATTGGTGGAAAAGAATAAAAGCATAGCCATCGTCGAACAGGGGACAGGTGGTCTCTTGCAAGCTGAATTGAGCCTGGCTT
TGGCTGATCAGCCGTATTTTAGCGGAGGAAAAGTCATCGGTCAGCTAGGGACAGAATCGGGCTGGCTATCAGAGGAAGCA
GACTGCATTCGGCAGGAGCTGCAAGCTGATTTAGGTTTGGCTGTGTCTGTGCTTATCAAACCGGAATCAACAGAGGACAA
CGTACTTGCAAAAGTATACCTCACTTTGGCTACGCCCTCGGGTATTTCCCAAAAAGAGATAGATTTAGGTGGTTATTCGT
GGCAATACCTTCGCCAGCTTGCTTGTCTGCAGGCCTGGGATTTTGTACGAAACACTTTGTGA

Domains

Predicted by InterproScan.

Damage-inducible protein CinA KH domain (CinA_KH)

(178-253)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-170)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus suis isolate S10

93.893

100

0.939
  cinA Streptococcus mutans UA159

57.908

100

0.606
  cinA Streptococcus mitis SK321

56.49

100

0.598
  cinA Streptococcus mitis NCTC 12261

56.25

100

0.595
  cinA Streptococcus pneumoniae TIGR4

56.01

100

0.593
  cinA Streptococcus pneumoniae Rx1

56.01

100

0.593
  cinA Streptococcus pneumoniae R6

56.01

100

0.593
  cinA Streptococcus pneumoniae D39

55.769

100

0.59
  cinA Bacillus subtilis subsp. subtilis str. 168

40.849

95.929

0.392