Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA   Type   Machinery gene
Locus tag   NI386_RS18960 Genome accession   NZ_CP099924
Coordinates   2314002..2314286 (-) Length   94 a.a.
NCBI ID   WP_021449594.1    Uniprot ID   -
Organism   Vibrio parahaemolyticus strain Isc7     
Function   dsDNA binding (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Genomic island 2313360..2323328 2314002..2314286 within 0


Gene organization within MGE regions


Location: 2313360..2323328
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NI386_RS18955 (NI386_19590) rrtA 2313360..2313911 (+) 552 WP_025540469.1 rhombosortase -
  NI386_RS18960 (NI386_19595) comEA 2314002..2314286 (-) 285 WP_021449594.1 ComEA family DNA-binding protein Machinery gene
  NI386_RS18965 (NI386_19600) ppiD 2314437..2316296 (-) 1860 WP_308390323.1 peptidylprolyl isomerase -
  NI386_RS18970 (NI386_19605) - 2316495..2316767 (-) 273 WP_005382341.1 HU family DNA-binding protein -
  NI386_RS18975 (NI386_19610) lon 2316960..2319311 (-) 2352 WP_015296438.1 endopeptidase La -
  NI386_RS18980 (NI386_19615) clpX 2319443..2320723 (-) 1281 WP_005460618.1 ATP-dependent protease ATP-binding subunit ClpX -
  NI386_RS18985 (NI386_19620) clpP 2320795..2321421 (-) 627 WP_005460620.1 ATP-dependent Clp endopeptidase proteolytic subunit ClpP -
  NI386_RS18990 (NI386_19625) tig 2321527..2322831 (-) 1305 WP_005460612.1 trigger factor -
  NI386_RS18995 (NI386_19630) - 2323125..2323310 (-) 186 WP_005482581.1 hypothetical protein -

Sequence

Protein


Download         Length: 94 a.a.        Molecular weight: 10249.91 Da        Isoelectric Point: 5.8425

>NTDB_id=702650 NI386_RS18960 WP_021449594.1 2314002..2314286(-) (comEA) [Vibrio parahaemolyticus strain Isc7]
MKWILTLCLVVFAPLSLAADTKADKYEGIEITVNINTASAEEIATMLKGIGEKKAQSIVDYRTEHGPFKTAADLTNVKGI
GEATIKKNEDRILL

Nucleotide


Download         Length: 285 bp        

>NTDB_id=702650 NI386_RS18960 WP_021449594.1 2314002..2314286(-) (comEA) [Vibrio parahaemolyticus strain Isc7]
ATGAAATGGATTTTAACCTTGTGTTTAGTGGTGTTCGCACCACTCAGTTTGGCCGCTGATACCAAGGCTGATAAATATGA
AGGAATTGAAATTACGGTCAATATCAATACTGCTTCTGCAGAAGAGATAGCAACGATGCTGAAAGGTATTGGCGAAAAGA
AAGCGCAAAGCATAGTTGACTACCGTACTGAGCACGGCCCATTTAAAACAGCAGCTGATTTAACCAATGTAAAAGGAATT
GGTGAAGCAACCATCAAGAAAAACGAAGACCGCATTCTTCTATAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(32-92)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA Vibrio parahaemolyticus RIMD 2210633

100

100

1
  comEA Vibrio campbellii strain DS40M4

77.895

100

0.787
  comEA Vibrio cholerae C6706

62.766

100

0.628
  comEA Vibrio cholerae strain A1552

62.766

100

0.628
  comEA/comE1 Glaesserella parasuis strain SC1401

56.452

65.957

0.372
  comE1/comEA Haemophilus influenzae Rd KW20

56.452

65.957

0.372
  comE Neisseria gonorrhoeae MS11

38.889

95.745

0.372
  comE Neisseria gonorrhoeae MS11

38.889

95.745

0.372
  comE Neisseria gonorrhoeae MS11

38.889

95.745

0.372
  comE Neisseria gonorrhoeae MS11

38.889

95.745

0.372
  comEA Acinetobacter baylyi ADP1

47.222

76.596

0.362