Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   ALSL_RS08520 Genome accession   NZ_AP018560
Coordinates   1827419..1828687 (+) Length   422 a.a.
NCBI ID   WP_126538281.1    Uniprot ID   A0A2Z6E6N1
Organism   Aerosticca soli strain Dysh456     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1822419..1833687
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ALSL_RS08495 (ALSL_1706) - 1823015..1824739 (-) 1725 WP_126538271.1 lysophospholipid acyltransferase family protein -
  ALSL_RS08500 (ALSL_1707) - 1824812..1825405 (-) 594 WP_126538273.1 YhgN family NAAT transporter -
  ALSL_RS08505 (ALSL_1708) - 1825439..1826209 (-) 771 WP_126538275.1 SDR family NAD(P)-dependent oxidoreductase -
  ALSL_RS08510 (ALSL_1709) grxD 1826206..1826532 (-) 327 WP_126538277.1 Grx4 family monothiol glutaredoxin -
  ALSL_RS08515 (ALSL_1710) - 1826642..1827220 (+) 579 WP_126538279.1 Fe-Mn family superoxide dismutase -
  ALSL_RS08520 (ALSL_1711) pilC 1827419..1828687 (+) 1269 WP_126538281.1 type II secretion system F family protein Machinery gene
  ALSL_RS08525 (ALSL_1712) pilD 1828814..1829671 (+) 858 WP_126538283.1 A24 family peptidase Machinery gene
  ALSL_RS08530 (ALSL_1713) coaE 1829668..1830339 (+) 672 WP_126538285.1 dephospho-CoA kinase -
  ALSL_RS08535 (ALSL_1714) - 1830412..1831413 (-) 1002 WP_126538287.1 HAMP domain-containing sensor histidine kinase -
  ALSL_RS08540 (ALSL_1715) - 1831420..1832145 (-) 726 WP_126538289.1 response regulator transcription factor -
  ALSL_RS08545 (ALSL_1716) - 1832231..1832845 (-) 615 WP_126538291.1 arylesterase -
  ALSL_RS08550 (ALSL_1717) - 1832844..1833542 (+) 699 WP_126538293.1 ATP-binding cassette domain-containing protein -

Sequence

Protein


Download         Length: 422 a.a.        Molecular weight: 45574.58 Da        Isoelectric Point: 10.2477

>NTDB_id=70061 ALSL_RS08520 WP_126538281.1 1827419..1828687(+) (pilC) [Aerosticca soli strain Dysh456]
MATATAAAKNARTLGAQRAEVSQLTLYDWVALDKRGKRMKGEMAAKNASLVKAELRRQGMNPQSVRERGKPLFGAAGSSV
KPRDVAIFSRQIATMMASGIPMVQAFDIIAGGQRNVRFKNMLTDVKQAIEGGSSLHEALARYPVQFDELYRNLVRAGESA
GVLDTVLDTVATYKEKMEAIKSKIKKALFYPTMVLAVALLVSMIMLLFVVPVFAQTFRDAGAELPAPTQVVISASEFMKS
YWWVVIGGIVGSIVAAVMAKKRSPAFAHALDRLSLRLPVIGNILRQSAIARFARTLGVTFRAGVPLVEAMDAVAGATGSV
VYGDAVRQMRDDIAVGHQLQLAMRQTGLFPNMVVQMTAIGEESGALDSMLFKVAEFYEEEVNNAVDTLSTLLEPLIMVIL
GVLVGGMVVSLYLPIFKLAGTV

Nucleotide


Download         Length: 1269 bp        

>NTDB_id=70061 ALSL_RS08520 WP_126538281.1 1827419..1828687(+) (pilC) [Aerosticca soli strain Dysh456]
ATGGCCACCGCTACCGCAGCCGCAAAAAACGCCCGCACGCTGGGCGCCCAACGCGCCGAAGTCAGCCAGCTGACGCTGTA
CGACTGGGTGGCGCTTGACAAGCGCGGCAAGCGCATGAAGGGCGAAATGGCGGCGAAGAATGCCTCGCTGGTCAAGGCCG
AGCTGCGCCGACAGGGCATGAACCCGCAAAGCGTGCGCGAACGCGGCAAGCCGCTCTTCGGCGCCGCCGGCAGTTCGGTC
AAGCCGCGCGACGTGGCCATCTTCAGCCGCCAGATCGCCACCATGATGGCCTCCGGCATCCCGATGGTGCAGGCCTTCGA
CATCATCGCCGGCGGGCAGAGGAACGTCCGCTTCAAGAACATGCTCACCGACGTGAAGCAGGCGATCGAGGGCGGCTCCT
CGCTGCACGAAGCGCTCGCACGCTACCCGGTGCAGTTCGACGAGCTCTATCGCAACCTGGTGCGCGCCGGCGAATCGGCG
GGCGTGCTGGATACCGTGCTCGACACCGTCGCCACCTACAAAGAAAAAATGGAGGCGATCAAGAGCAAGATCAAAAAAGC
CCTGTTCTATCCGACCATGGTGCTGGCGGTGGCGCTGCTGGTCAGCATGATCATGCTCTTGTTCGTGGTGCCGGTGTTCG
CGCAGACCTTCCGCGACGCCGGCGCGGAGCTGCCGGCGCCCACGCAGGTCGTCATCTCGGCCTCGGAGTTCATGAAAAGC
TACTGGTGGGTGGTGATCGGCGGCATCGTCGGCAGCATCGTCGCGGCGGTGATGGCCAAAAAGCGCTCGCCGGCCTTCGC
CCATGCGCTGGACCGGCTGTCCCTGCGCCTGCCGGTGATCGGCAACATCCTGCGCCAGTCGGCGATCGCCCGCTTCGCGC
GCACTCTCGGTGTCACCTTCCGCGCCGGCGTGCCGCTGGTGGAGGCCATGGACGCGGTGGCCGGCGCCACCGGCAGCGTG
GTCTACGGGGATGCGGTCAGGCAGATGCGCGACGACATCGCCGTCGGTCACCAGTTGCAGCTGGCGATGCGTCAGACCGG
CCTGTTTCCGAACATGGTGGTGCAGATGACCGCGATCGGCGAGGAATCCGGCGCGCTGGACAGCATGTTGTTCAAGGTGG
CCGAGTTCTATGAGGAAGAGGTCAACAACGCGGTCGACACCCTCTCCACTCTGCTCGAGCCCTTGATCATGGTGATCCTG
GGCGTGCTGGTGGGCGGCATGGTGGTCTCGCTTTATCTGCCGATCTTCAAGCTGGCCGGCACGGTCTAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(292-414)

Type II secretion system (T2SS), protein F (T2SSF)

(88-211)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2Z6E6N1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Legionella pneumophila strain ERS1305867

53.885

94.55

0.509
  pilC Pseudomonas stutzeri DSM 10701

52.261

94.313

0.493
  pilC Acinetobacter baylyi ADP1

47.561

97.156

0.462
  pilC Acinetobacter baumannii D1279779

49.118

94.076

0.462
  pilG Neisseria meningitidis 44/76-A

42.487

91.469

0.389
  pilG Neisseria gonorrhoeae MS11

42.487

91.469

0.389
  pilC Vibrio campbellii strain DS40M4

39.798

94.076

0.374
  pilC Vibrio cholerae strain A1552

39.848

93.365

0.372
  pilC Thermus thermophilus HB27

38.272

95.972

0.367

Multiple sequence alignment