Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   M5C73_RS11700 Genome accession   NZ_CP098790
Coordinates   2346063..2347289 (+) Length   408 a.a.
NCBI ID   WP_058203705.1    Uniprot ID   -
Organism   Lactococcus lactis strain WiKim0124     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2341063..2352289
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  M5C73_RS11675 (M5C73_11675) - 2342154..2342957 (-) 804 WP_003130590.1 phosphatidate cytidylyltransferase -
  M5C73_RS11680 (M5C73_11680) - 2342957..2343691 (-) 735 WP_003130589.1 isoprenyl transferase -
  M5C73_RS11685 (M5C73_11685) yajC 2344064..2344396 (-) 333 WP_003130588.1 preprotein translocase subunit YajC -
  M5C73_RS11690 (M5C73_11690) - 2344491..2345189 (-) 699 WP_033900689.1 DNA alkylation repair protein -
  M5C73_RS11695 (M5C73_11695) rlmH 2345208..2345687 (-) 480 WP_003130585.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  M5C73_RS11700 (M5C73_11700) htrA 2346063..2347289 (+) 1227 WP_058203705.1 S1C family serine protease Regulator
  M5C73_RS11705 (M5C73_11705) - 2347415..2348413 (+) 999 WP_023189027.1 glycosyltransferase family 4 protein -
  M5C73_RS11710 (M5C73_11710) - 2348539..2349879 (+) 1341 WP_010906331.1 glycosyltransferase family 4 protein -
  M5C73_RS11715 (M5C73_11715) - 2349987..2350211 (+) 225 WP_003130579.1 YkuJ family protein -
  M5C73_RS11720 (M5C73_11720) - 2350353..2351357 (+) 1005 WP_252160130.1 hypothetical protein -
  M5C73_RS11725 (M5C73_11725) - 2351397..2352149 (-) 753 WP_003130577.1 tRNA1(Val) (adenine(37)-N6)-methyltransferase -

Sequence

Protein


Download         Length: 408 a.a.        Molecular weight: 41607.90 Da        Isoelectric Point: 4.9794

>NTDB_id=697998 M5C73_RS11700 WP_058203705.1 2346063..2347289(+) (htrA) [Lactococcus lactis strain WiKim0124]
MAKANIGKLLLTGVVGGAIALGGSAIYQSTTNQSANNSRSNTTSTKVSNVSVNVNTDVTSAIKKVSNSVVSVMNYQKDNS
QSSDFSSIFGGNSGSSSSTDGLQLSSEGSGVIYKKSGGDAYVVTNYHVIAGNSSLDVLLSGGQKVKASVVGYDEYTDLAV
LKISSEHVKDVAAFADSSKLTIGEPAIAVGSPLGSQFANTATEGILSATSRQVTLTQENGQTTNINAIQTDAAINPGNSG
GALINIEGQVIGITQSKITTTEDGSTSVEGLGFAIPSNDVVNIINKLEADGKISRPALGIRMVDLSQLSTNDSSQLKLPS
SVTGGVVVYSVQSGLPAASAGLKAGDVITKVGDTAVTSSTDLQSALYSHNINDTVKVTYYRDGKSNTADVKLSKSTSDLE
TSSSSSSN

Nucleotide


Download         Length: 1227 bp        

>NTDB_id=697998 M5C73_RS11700 WP_058203705.1 2346063..2347289(+) (htrA) [Lactococcus lactis strain WiKim0124]
ATGGCAAAAGCTAATATAGGAAAATTGCTATTAACAGGTGTCGTGGGCGGAGCCATCGCACTTGGAGGAAGTGCAATCTA
TCAAAGCACTACAAATCAATCGGCAAATAATAGTCGTTCAAATACAACTAGTACAAAGGTTAGTAACGTTTCGGTAAATG
TCAATACCGATGTTACCTCTGCAATTAAAAAAGTTTCAAATTCTGTCGTTTCTGTTATGAATTATCAAAAAGATAACTCA
CAAAGTAGTGACTTCAGTTCAATTTTTGGTGGAAATAGCGGTTCAAGTTCATCGACTGATGGCTTACAGCTTTCTAGTGA
AGGCTCTGGTGTCATCTACAAAAAATCTGGTGGTGATGCCTACGTTGTAACTAACTACCACGTTATTGCTGGTAATAGCT
CACTTGATGTTCTGCTTTCTGGTGGACAAAAAGTTAAAGCTTCTGTGGTTGGTTATGATGAATACACAGACCTTGCTGTT
CTTAAAATCAGTTCTGAACATGTCAAAGATGTGGCGGCATTCGCTGATTCTAGTAAATTAACAATTGGTGAACCTGCCAT
TGCCGTTGGCTCACCTTTAGGTAGTCAATTTGCTAACACCGCAACTGAAGGAATTTTATCTGCAACAAGCCGTCAAGTGA
CTTTGACCCAAGAAAATGGTCAAACAACTAATATCAATGCAATTCAAACAGATGCTGCCATTAACCCTGGTAACTCTGGA
GGGGCTTTGATTAATATTGAAGGACAAGTTATTGGAATTACTCAAAGTAAAATTACAACAACTGAAGATGGTTCTACTTC
TGTCGAAGGTTTAGGATTTGCGATTCCTTCTAATGATGTCGTAAATATCATTAATAAACTTGAAGCTGATGGTAAGATTT
CACGCCCTGCTTTAGGTATCCGAATGGTTGACCTTTCACAATTATCAACAAATGACAGTTCTCAATTGAAATTACCAAGC
AGTGTAACAGGTGGGGTTGTTGTTTACTCCGTCCAATCTGGACTTCCTGCTGCCTCAGCTGGTTTGAAAGCTGGAGATGT
AATTACAAAGGTTGGCGATACAGCAGTAACTTCTTCAACAGACTTGCAAAGTGCTCTTTACTCACACAATATCAATGATA
CAGTAAAAGTTACTTATTATCGTGATGGTAAATCAAATACAGCAGATGTTAAACTTTCTAAATCAACCAGTGACTTAGAA
ACAAGCAGTTCATCTTCTTCTAATTAA

Domains

Predicted by InterproScan.

Peptidase family M50 (Peptidase_M50)

(223-396)

Trypsin-like peptidase domain (Trypsin_2)

(108-253)

PDZ domain (PDZ_2)

(296-392)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mitis NCTC 12261

56.283

93.627

0.527
  htrA Streptococcus gordonii str. Challis substr. CH1

54.476

95.833

0.522
  htrA Streptococcus pneumoniae D39

58.309

84.069

0.49
  htrA Streptococcus pneumoniae TIGR4

58.309

84.069

0.49
  htrA Streptococcus pneumoniae R6

58.309

84.069

0.49
  htrA Streptococcus pneumoniae Rx1

58.309

84.069

0.49
  htrA Streptococcus mutans UA159

52.989

90.196

0.478