Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA   Type   Machinery gene
Locus tag   SR187_RS06615 Genome accession   NZ_AP018400
Coordinates   1391870..1392526 (-) Length   218 a.a.
NCBI ID   WP_024532637.1    Uniprot ID   -
Organism   Streptococcus ruminantium strain GUT-187     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1386870..1397526
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SR187_RS06595 (SR187_6740) sodA 1386899..1387510 (-) 612 WP_024532641.1 superoxide dismutase SodA -
  SR187_RS06600 (SR187_6745) holA 1387607..1388638 (-) 1032 WP_120172488.1 DNA polymerase III subunit delta -
  SR187_RS06605 (SR187_6750) - 1388894..1389505 (-) 612 WP_231996430.1 hypothetical protein -
  SR187_RS06610 (SR187_6755) comEC/celB 1389652..1391886 (-) 2235 WP_120171914.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  SR187_RS06615 (SR187_6760) comEA 1391870..1392526 (-) 657 WP_024532637.1 helix-hairpin-helix domain-containing protein Machinery gene
  SR187_RS06620 (SR187_6765) - 1392611..1393354 (-) 744 WP_024532636.1 1-acyl-sn-glycerol-3-phosphate acyltransferase -
  SR187_RS06625 (SR187_6770) - 1393544..1394989 (+) 1446 WP_120171915.1 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L- lysine ligase -
  SR187_RS06630 (SR187_6775) - 1395348..1396136 (+) 789 WP_120171916.1 ABC transporter ATP-binding protein -
  SR187_RS06635 (SR187_6780) - 1396146..1397075 (+) 930 WP_120171917.1 ABC transporter substrate-binding protein -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23008.77 Da        Isoelectric Point: 4.4459

>NTDB_id=69456 SR187_RS06615 WP_024532637.1 1391870..1392526(-) (comEA) [Streptococcus ruminantium strain GUT-187]
MEKVIECIKEYKWQVGLPVIAVVVVASFLLFRQSAQPVDQTGLTKFSQTEQISSSQEVIEETSTEASEKNSKLVVDVKGA
VINPGLYTLETGARINDAIAAAGGFTSQADQKSINLAQKLTDETVVYVASQGENISVVPNSSTSSALSQEGNKSGLVNLN
TATVADLQTISGIGAKRAADIIAYREANGSFKSVDDLSNVSGIGDKTLESIRSYVTVG

Nucleotide


Download         Length: 657 bp        

>NTDB_id=69456 SR187_RS06615 WP_024532637.1 1391870..1392526(-) (comEA) [Streptococcus ruminantium strain GUT-187]
ATGGAAAAAGTTATTGAATGCATTAAAGAATACAAGTGGCAAGTTGGTCTGCCTGTGATAGCAGTAGTGGTGGTGGCGAG
TTTTCTTCTTTTTAGACAGTCAGCTCAGCCAGTTGACCAGACAGGATTGACCAAGTTTTCACAGACAGAACAAATCAGCT
CCAGTCAAGAAGTGATAGAAGAGACCTCAACAGAAGCTAGCGAGAAAAACAGCAAACTAGTGGTGGATGTCAAGGGTGCA
GTGATAAATCCCGGTCTTTACACCTTAGAGACTGGTGCCCGTATCAATGATGCTATTGCCGCAGCGGGCGGTTTCACTAG
TCAAGCAGATCAAAAATCTATCAATCTAGCACAAAAGCTGACTGATGAAACAGTCGTCTATGTGGCTAGTCAGGGTGAGA
ATATTTCGGTAGTTCCCAATTCTTCAACTAGCTCAGCCCTGTCTCAAGAGGGAAATAAATCTGGTCTAGTTAATCTGAAT
ACAGCTACGGTGGCGGACTTACAGACCATTTCAGGCATCGGTGCTAAGCGAGCAGCGGATATTATTGCTTATCGTGAAGC
CAATGGTTCTTTCAAGTCGGTGGACGATCTCAGCAATGTTTCTGGCATTGGTGACAAGACCCTAGAAAGTATCCGATCCT
ATGTTACGGTTGGATAA

Domains

Predicted by InterproScan.

SLBB domain (SLBB)

(74-128)

Helix-hairpin-helix motif (HHH_3)

(155-216)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA Streptococcus thermophilus LMD-9

47.807

100

0.5
  comEA/celA/cilE Streptococcus pneumoniae Rx1

46.637

100

0.477
  comEA/celA/cilE Streptococcus pneumoniae D39

46.637

100

0.477
  comEA/celA/cilE Streptococcus pneumoniae R6

46.637

100

0.477
  comEA/celA/cilE Streptococcus mitis NCTC 12261

46.637

100

0.477
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

46.119

100

0.463
  comEA/celA/cilE Streptococcus mitis SK321

44.495

100

0.445
  comEA Lactococcus lactis subsp. cremoris KW2

41.441

100

0.422
  comEA Bacillus subtilis subsp. subtilis str. 168

42.632

87.156

0.372

Multiple sequence alignment