Detailed information NTG0069455

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: SR187_RS06610
• Genome accession: NZ_AP018400
• Coordinates: 1389652..1391886 (-)
• Length: 744 a.a.
• NCBI ID: WP_120171914.1
• Uniprot ID: -
• Organism: Streptococcus ruminantium strain GUT-187
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1384652..1396886

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SR187_RS06580 (SR187_6725)	-	1385357..1385521 (-)	165	WP_120171911.1	transposon-encoded TnpW family protein	-
SR187_RS06585 (SR187_6730)	-	1385648..1386271 (-)	624	WP_120171912.1	helix-turn-helix domain-containing protein	-
SR187_RS10240	-	1386517..1386707 (-)	191	Protein_1241	recombinase	-
SR187_RS06595 (SR187_6740)	sodA	1386899..1387510 (-)	612	WP_024532641.1	superoxide dismutase SodA	-
SR187_RS06600 (SR187_6745)	holA	1387607..1388638 (-)	1032	WP_120172488.1	DNA polymerase III subunit delta	-
SR187_RS06605 (SR187_6750)	-	1388894..1389505 (-)	612	WP_231996430.1	hypothetical protein	-
SR187_RS06610 (SR187_6755)	comEC/celB	1389652..1391886 (-)	2235	WP_120171914.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
SR187_RS06615 (SR187_6760)	comEA	1391870..1392526 (-)	657	WP_024532637.1	helix-hairpin-helix domain-containing protein	Machinery gene
SR187_RS06620 (SR187_6765)	-	1392611..1393354 (-)	744	WP_024532636.1	1-acyl-sn-glycerol-3-phosphate acyltransferase	-
SR187_RS06625 (SR187_6770)	-	1393544..1394989 (+)	1446	WP_120171915.1	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L- lysine ligase	-
SR187_RS06630 (SR187_6775)	-	1395348..1396136 (+)	789	WP_120171916.1	ABC transporter ATP-binding protein	-

Sequence

Protein

• Length: 744 a.a.
• Molecular weight: 84904.77 Da
• Isoelectric Point: 9.7221

>NTDB_id=69455 SR187_RS06610 WP_120171914.1 1389652..1391886(-) (comEC/celB) [Streptococcus ruminantium strain GUT-187]
MLRLDKLPCQPIHLAILAVVTYFTVHRFSMLTMSLLILLLVIYWRRQGKLTFFKMLPLLVLCGLFFGCQKLKWKQEEQAV
SKQVTAVEIVPDTININGDQLSFRARTDGQIYQGFYKLTSQKEQEYFQKLTALVQVEVKAETSLPSGQRNFNGFDYQAYL
KTQGIYRILTIATINKIVPIHSWNPMDWLSIWRRKALVFIKSNFPSPMSHYMTGLLFGELDSDFDQMSALYSSLGIIHLF
ALSGMQVGFFIDKFRWILLRLGLTKETVDQLQVPFSFVYAGLTGFSVSVVRSLIQKILSNLGLRKLDNFAATLFICFLVQ
PRFLLTVGGVLTFTYAFLLTVFDFEDLKQIKKVVVESLSISLGILPILMTYFFAFQPLSILLTFFFSFVFDVLLLPSLSV
IFLLSPLVKITWVNSFFVLMEKMIIWVSDLGLRPLILGKPSDFILLVLLLGFFMLYDFHRQKKWLLGLSLLLTLLFFITK
HPLENEVTVVDIGQGDSIFLRDMQGRTVLIDVGGRVDFTVKEGWKARSRQANAERTLIPYLHSRGVDKIDSLVLTHTDTD
HVGDVLEVAKNFKIGKIYVSSGSLTVPSFVTTLKKINVPVHVVQVGDRLPIVDSYLEVLYPSRSGDGSNNDSIVLYGRLL
GINFLFTGDLEEGELELIKTYPKLSVDVLKAGHHGSKGSSYPEFLDHIGAKIALISAGEKNRYKHPHQETLERFEQKNMQ
IYRTDRQGAIRFRGWRSWSIETVR

Nucleotide

• Length: 2235 bp

>NTDB_id=69455 SR187_RS06610 WP_120171914.1 1389652..1391886(-) (comEC/celB) [Streptococcus ruminantium strain GUT-187]
ATGTTACGGTTGGATAAGCTTCCCTGTCAGCCTATACATCTAGCCATTTTGGCGGTCGTGACCTACTTTACGGTTCACCG
TTTTTCGATGTTGACAATGAGCCTTCTGATATTATTATTGGTAATCTATTGGCGGCGTCAGGGGAAACTTACTTTTTTTA
AAATGCTGCCGCTTCTAGTCTTATGCGGTCTATTCTTCGGCTGCCAAAAGCTCAAATGGAAACAGGAAGAGCAGGCTGTT
TCAAAGCAAGTGACTGCTGTAGAGATTGTGCCGGATACTATAAATATCAATGGCGATCAGTTATCTTTCCGTGCTAGGAC
TGATGGTCAGATTTACCAAGGTTTCTACAAACTAACTAGTCAGAAAGAACAGGAGTATTTCCAAAAGCTAACAGCTCTTG
TTCAGGTGGAGGTGAAGGCAGAGACAAGTCTCCCATCAGGTCAGCGGAATTTCAATGGTTTTGATTATCAAGCCTATTTA
AAAACACAGGGAATCTATCGAATCCTCACCATAGCGACTATCAATAAGATCGTACCTATTCACTCTTGGAACCCTATGGA
TTGGTTGTCAATTTGGCGGAGAAAAGCCTTGGTTTTCATCAAATCTAATTTTCCTTCCCCCATGAGCCATTACATGACAG
GGTTGCTTTTTGGAGAGTTGGACAGTGACTTTGATCAGATGAGCGCCCTTTACTCCAGTCTGGGGATTATCCATCTCTTT
GCTCTATCAGGAATGCAGGTAGGTTTTTTCATTGATAAGTTTCGCTGGATTTTACTGCGTTTAGGCTTGACAAAGGAGAC
AGTTGATCAATTACAAGTCCCCTTTTCTTTTGTCTATGCTGGTTTGACAGGCTTTTCTGTATCAGTCGTCCGGTCTTTGA
TTCAGAAAATTTTGAGCAACCTGGGGCTTCGGAAGCTGGATAACTTTGCTGCAACACTCTTTATTTGTTTCTTGGTGCAG
CCTCGTTTTCTCCTGACAGTTGGAGGTGTCTTGACATTTACCTATGCTTTTTTGTTGACGGTCTTTGATTTTGAAGACTT
GAAGCAAATCAAAAAGGTTGTAGTGGAAAGTCTGAGTATTTCTCTGGGGATTCTGCCAATTCTGATGACCTATTTTTTCG
CTTTTCAGCCCCTATCTATTCTACTAACCTTCTTCTTTTCCTTTGTTTTTGATGTATTGCTTTTGCCGAGTCTATCTGTA
ATTTTTCTTTTATCTCCCTTGGTCAAGATTACTTGGGTCAATTCTTTCTTTGTTTTGATGGAGAAAATGATTATTTGGGT
ATCGGATTTGGGTCTTCGACCTTTGATACTAGGGAAACCGTCTGACTTCATCTTGTTAGTCTTGTTACTGGGATTTTTCA
TGCTTTACGATTTTCATAGACAGAAAAAATGGCTGTTAGGATTGAGTTTGCTCCTTACTCTGCTATTTTTCATTACAAAA
CATCCATTAGAAAATGAAGTAACTGTCGTAGATATCGGACAGGGAGATAGTATCTTTTTGCGAGATATGCAGGGGCGTAC
GGTTCTAATTGACGTTGGTGGACGGGTGGATTTTACGGTCAAGGAAGGCTGGAAGGCGCGATCCCGTCAGGCTAATGCAG
AGAGGACCTTGATTCCTTATCTACATAGTCGAGGTGTGGACAAGATTGACAGTTTGGTGTTGACGCACACCGATACTGAC
CATGTGGGCGATGTTCTGGAAGTAGCTAAGAATTTTAAGATCGGAAAGATCTATGTGTCTTCAGGTAGTTTGACAGTCCC
TAGCTTTGTAACCACCTTGAAAAAAATCAATGTACCTGTTCATGTTGTGCAGGTGGGTGATCGCCTACCGATTGTTGATT
CCTATTTGGAAGTGCTCTATCCGAGCCGATCGGGTGATGGTAGCAACAATGATTCTATTGTCCTCTATGGACGGCTCCTT
GGAATCAATTTTCTGTTTACGGGTGATCTGGAGGAGGGGGAATTAGAGCTGATAAAAACCTATCCCAAATTGTCAGTTGA
TGTTCTAAAAGCTGGACACCATGGTTCAAAAGGTTCTTCTTATCCTGAATTTTTAGACCATATTGGAGCTAAGATTGCCT
TAATCTCGGCTGGTGAGAAAAATCGCTACAAGCATCCCCATCAAGAAACCTTGGAGCGTTTTGAACAGAAGAATATGCAA
ATCTATCGGACAGACCGGCAAGGAGCTATTCGCTTTAGAGGTTGGCGAAGTTGGTCAATTGAAACGGTGAGATGA

Domains

Predicted by InterproScan.

• Metallo-beta-lactamase superfamily (Lactamase_B) (493-697)

• Domain of unknown function (DUF4131) (DUF4131) (31-176)

• Competence protein (Competence) (215-459)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis SK321	53.28	100	0.535
comEC/celB	Streptococcus mitis NCTC 12261	52.695	99.731	0.526
comEC/celB	Streptococcus pneumoniae TIGR4	51.548	99.866	0.515
comEC/celB	Streptococcus pneumoniae Rx1	51.009	99.866	0.509
comEC/celB	Streptococcus pneumoniae D39	51.009	99.866	0.509
comEC/celB	Streptococcus pneumoniae R6	51.009	99.866	0.509
comEC	Lactococcus lactis subsp. cremoris KW2	47.709	99.731	0.476