Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   STO1_RS01345 Genome accession   NZ_AP018338
Coordinates   258134..259390 (+) Length   418 a.a.
NCBI ID   WP_096421635.1    Uniprot ID   A0A224A4V4
Organism   Streptococcus oralis subsp. tigurinus strain osk_001     
Function   facilitate localization of RecA (predicted from homology)   
Homologous recombination

Genomic Context

Location: 253134..264390
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  STO1_RS01320 (STO1_002580) ndk 254796..255215 (+) 420 WP_007520750.1 nucleoside-diphosphate kinase -
  STO1_RS01325 comM 255352..255975 (+) 624 WP_007520749.1 hypothetical protein Regulator
  STO1_RS01330 (STO1_002590) tsaE 256061..256504 (+) 444 WP_007520747.1 tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE -
  STO1_RS01335 (STO1_002600) - 256494..257015 (+) 522 WP_021164629.1 GNAT family N-acetyltransferase -
  STO1_RS01340 (STO1_002610) brpA 257020..258060 (+) 1041 WP_061588622.1 biofilm formation/cell division transcriptional regulator BrpA -
  STO1_RS01345 (STO1_002620) cinA 258134..259390 (+) 1257 WP_096421635.1 competence/damage-inducible protein A Machinery gene
  STO1_RS01350 (STO1_002630) recA 259445..260596 (+) 1152 WP_096421637.1 recombinase RecA Machinery gene
  STO1_RS01355 (STO1_002640) - 260716..261270 (-) 555 WP_000060287.1 GNAT family N-acetyltransferase -
  STO1_RS01360 (STO1_002650) - 261380..262750 (+) 1371 WP_061588624.1 MATE family efflux transporter -
  STO1_RS01365 (STO1_002660) - 262846..263562 (+) 717 WP_000532898.1 YebC/PmpR family DNA-binding transcriptional regulator -
  STO1_RS01370 (STO1_002670) - 263610..264296 (-) 687 WP_045617726.1 DUF308 domain-containing protein -

Sequence

Protein


Download         Length: 418 a.a.        Molecular weight: 45096.49 Da        Isoelectric Point: 4.8315

>NTDB_id=69037 STO1_RS01345 WP_096421635.1 258134..259390(+) (cinA) [Streptococcus oralis subsp. tigurinus strain osk_001]
MKAEIIAVGTEILTGQIVNTNAQFLSEKLAEIGVDVYFQTAVGDNEARLLSLLEIASQRSNLVILTGGLGPTEDDLTKQT
LAKFLGKELAFDPQSQAKLDVFFAQRPDYARTPNNERQAQLVAGSTPLPNETGLAVGGILEVDGVAYVVLPGPPSELKPM
VLNQLLPKLMTGTKLYSRVLRFFGIGESQLVTILADLIDQQTDPTLAPYAKTGEVTLRLSTKAVSQEKADQVLDILENQI
LDRQTFEGISLRDICYGYGEETSLASVVVEELKKRQKSITAAESLTAGLFQATLADFSGVSAIFNGGFVTYSLEEKSKML
DISEQELKEHGVVSEFTARKMAEQARLKTQSDYGVSLTGVAGPDSLEGHPAGTVFIGLAHAKGTEVIKANIAGRSRADVR
HIAVMHAFNLVRKALLSD

Nucleotide


Download         Length: 1257 bp        

>NTDB_id=69037 STO1_RS01345 WP_096421635.1 258134..259390(+) (cinA) [Streptococcus oralis subsp. tigurinus strain osk_001]
ATGAAAGCAGAAATTATTGCTGTTGGAACAGAAATTTTAACAGGGCAAATCGTCAATACCAATGCTCAGTTTTTATCAGA
GAAGCTAGCCGAAATTGGGGTAGATGTCTACTTCCAAACAGCTGTCGGAGACAATGAAGCTCGTCTTTTGTCCTTGCTTG
AGATTGCGAGCCAACGTAGTAATCTTGTGATTTTGACAGGGGGCTTGGGACCAACTGAGGATGATTTGACCAAACAAACT
CTAGCTAAATTTTTAGGGAAAGAATTAGCCTTCGATCCTCAGTCGCAGGCAAAGTTGGATGTCTTTTTTGCTCAGAGACC
AGACTATGCGAGAACACCAAATAATGAAAGACAAGCTCAACTTGTAGCAGGGTCGACTCCACTACCAAACGAAACAGGAT
TGGCTGTTGGAGGAATCTTAGAAGTGGATGGCGTAGCCTACGTGGTCCTTCCGGGACCGCCAAGTGAGTTGAAACCCATG
GTCTTAAATCAACTTTTACCCAAGCTGATGACAGGCACCAAACTATATTCCCGAGTGCTTCGTTTCTTTGGAATTGGTGA
GAGTCAGTTGGTGACCATTTTGGCGGACTTGATTGACCAGCAAACGGATCCGACCTTGGCTCCTTATGCCAAGACGGGAG
AAGTGACTTTGCGCCTGTCTACAAAAGCAGTTAGTCAAGAAAAGGCTGATCAAGTACTGGATATCTTAGAAAATCAAATC
TTGGATCGCCAGACTTTTGAGGGAATTTCTCTGCGCGACATCTGTTATGGATATGGGGAAGAAACCAGCCTCGCAAGTGT
CGTTGTAGAAGAGCTAAAGAAGAGACAGAAAAGCATTACTGCGGCAGAAAGCTTGACGGCAGGTCTCTTTCAGGCTACTT
TAGCAGACTTTTCAGGTGTTTCAGCTATCTTTAATGGAGGGTTTGTCACCTACAGCCTAGAAGAAAAGTCCAAGATGTTG
GATATTTCCGAGCAAGAGCTAAAAGAACACGGGGTCGTTTCTGAGTTTACGGCTCGAAAAATGGCAGAGCAGGCACGGCT
CAAGACTCAGTCTGATTATGGAGTCAGTCTGACAGGTGTAGCTGGGCCAGATAGCCTAGAGGGGCATCCCGCCGGCACAG
TTTTTATTGGACTGGCACATGCAAAAGGGACAGAGGTTATCAAGGCTAATATTGCAGGACGGAGTCGAGCAGATGTTCGA
CATATTGCGGTCATGCATGCCTTTAACCTAGTTCGCAAGGCTTTATTAAGTGACTAA

Domains

Predicted by InterproScan.

Competence-damaged protein (CinA)

(262-414)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)

Damage-inducible protein CinA KH domain (CinA_KH)

(177-243)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A224A4V4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mitis SK321

89.952

100

0.9
  cinA Streptococcus mitis NCTC 12261

89.474

100

0.895
  cinA Streptococcus pneumoniae TIGR4

88.038

100

0.88
  cinA Streptococcus pneumoniae Rx1

88.038

100

0.88
  cinA Streptococcus pneumoniae R6

88.038

100

0.88
  cinA Streptococcus pneumoniae D39

87.799

100

0.878
  cinA Streptococcus mutans UA159

70.335

100

0.703
  cinA Streptococcus suis isolate S10

54.327

99.522

0.541
  cinA Bacillus subtilis subsp. subtilis str. 168

44.976

100

0.45

Multiple sequence alignment