Detailed information    

insolico Bioinformatically predicted

Overview


Name   comC   Type   Regulator
Locus tag   STO1_RS00030 Genome accession   NZ_AP018338
Coordinates   4686..4808 (+) Length   40 a.a.
NCBI ID   WP_007520968.1    Uniprot ID   A0A0F2DVB4
Organism   Streptococcus oralis subsp. tigurinus strain osk_001     
Function   binding to ComD; induce autophosphorylation of ComD (predicted from homology)   
Competence regulation

Genomic Context


Location: 1..9808
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  STO1_RS00005 (STO1_000010) dnaA 154..1515 (-) 1362 WP_007520973.1 chromosomal replication initiator protein DnaA -
  STO1_RS00010 (STO1_000020) spo0J 1732..2490 (-) 759 WP_045618162.1 ParB/RepB/Spo0J family partition protein Regulator
  STO1_RS00015 (STO1_000030) htrA 2548..3738 (-) 1191 WP_007520971.1 S1C family serine protease Regulator
  STO1_RS00020 (STO1_000040) rlmH 3924..4403 (+) 480 WP_007520969.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  STO1_RS00030 (STO1_000050) comC 4686..4808 (+) 123 WP_007520968.1 competence-stimulating peptide ComC Regulator
  STO1_RS00035 (STO1_000060) comD 4821..6140 (+) 1320 WP_007520967.1 competence system sensor histidine kinase ComD Regulator
  STO1_RS00040 (STO1_000070) comE 6137..6889 (+) 753 WP_000866082.1 competence system response regulator transcription factor ComE Regulator
  STO1_RS00055 (STO1_000080) - 7130..7672 (-) 543 WP_007520966.1 TetR/AcrR family transcriptional regulator -

Sequence


Protein


Download         Length: 40 a.a.        Molecular weight: 4939.71 Da        Isoelectric Point: 9.8677

>NTDB_id=69024 STO1_RS00030 WP_007520968.1 4686..4808(+) (comC) [Streptococcus oralis subsp. tigurinus strain osk_001]
MKNTVKLEQFKEVTEAELQEIRGGEIRKENNFLFYFFKRK

Nucleotide


Download         Length: 123 bp        

>NTDB_id=69024 STO1_RS00030 WP_007520968.1 4686..4808(+) (comC) [Streptococcus oralis subsp. tigurinus strain osk_001]
ATGAAAAATACAGTAAAATTGGAACAATTTAAAGAGGTAACAGAGGCAGAATTGCAGGAGATTCGAGGTGGAGAAATTAG
AAAGGAAAATAATTTTTTATTTTATTTTTTTAAAAGAAAGTAA

Domains


Predicted by InterproScan.

(1-29)


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure
  AlphaFold DB A0A0F2DVB4

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comC Streptococcus mitis NCTC 12261

57.5

100

0.575

  comC/comC2 Streptococcus pneumoniae TIGR4

55

100

0.55

  comC/comC2 Streptococcus pneumoniae A66

55

100

0.55

  comC Streptococcus mitis SK321

55

100

0.55

  comC/comC1 Streptococcus pneumoniae G54

52.5

100

0.525

  comC/comC1 Streptococcus pneumoniae R6

52.5

100

0.525

  comC/comC1 Streptococcus pneumoniae D39

52.5

100

0.525

  comC/comC1 Streptococcus pneumoniae Rx1

52.5

100

0.525

  comC/comC2 Streptococcus gordonii strain NCTC7865

43.243

92.5

0.4


Multiple sequence alignment