Detailed information NTG0069023

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: STO1_RS00015
• Genome accession: NZ_AP018338
• Coordinates: 2548..3738 (-)
• Length: 396 a.a.
• NCBI ID: WP_007520971.1
• Uniprot ID: -
• Organism: Streptococcus oralis subsp. tigurinus strain osk_001
• Function: repress competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1..8738

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
STO1_RS00005 (STO1_000010)	dnaA	154..1515 (-)	1362	WP_007520973.1	chromosomal replication initiator protein DnaA	-
STO1_RS00010 (STO1_000020)	spo0J	1732..2490 (-)	759	WP_045618162.1	ParB/RepB/Spo0J family partition protein	Regulator
STO1_RS00015 (STO1_000030)	htrA	2548..3738 (-)	1191	WP_007520971.1	S1C family serine protease	Regulator
STO1_RS00020 (STO1_000040)	rlmH	3924..4403 (+)	480	WP_007520969.1	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	-
STO1_RS00030 (STO1_000050)	comC	4686..4808 (+)	123	WP_007520968.1	competence-stimulating peptide ComC	Regulator
STO1_RS00035 (STO1_000060)	comD	4821..6140 (+)	1320	WP_007520967.1	competence system sensor histidine kinase ComD	Regulator
STO1_RS00040 (STO1_000070)	comE	6137..6889 (+)	753	WP_000866082.1	competence system response regulator transcription factor ComE	Regulator
STO1_RS00055 (STO1_000080)	-	7130..7672 (-)	543	WP_007520966.1	TetR/AcrR family transcriptional regulator	-

Sequence

Protein

• Length: 396 a.a.
• Molecular weight: 42029.95 Da
• Isoelectric Point: 6.5093

>NTDB_id=69023 STO1_RS00015 WP_007520971.1 2548..3738(-) (htrA) [Streptococcus oralis subsp. tigurinus strain osk_001]
MKHLQKFYKKGVKVLVIILIGFLSGALGSFVTLQLYQKQGNQATNNNSGTVTQTSYKNENSTTQAVNKIKDAVVSVITYS
ANKQSSVFGTEESNSDTDNQQIASEGSGVIYRKNENDAYIVTNTHVINGASKVDIRLADGTKVPGEIIGSDTFSDIAVVK
ISSEKVTTVAEFGDSSQLNVGETAIAIGSPLGSEYANTVTQGIISSLNRNVSLKSEDGQAISTKAIQTDTAINPGNSGGP
LVNIQGQVIGITSSKIASNGGTSVEGLGFAIPSNDVQNIIKQLESDGKVTRPALGIQMVNLSNVGANDLRKLNIPSGLTS
GVVVRSVQSNMPANGHLQKYDVITKVDDKEITSSTDLQYALYNHAIGDTIKITYYRNGKEETTSIKLDKNSGDLER

Nucleotide

• Length: 1191 bp

>NTDB_id=69023 STO1_RS00015 WP_007520971.1 2548..3738(-) (htrA) [Streptococcus oralis subsp. tigurinus strain osk_001]
ATGAAACACTTACAAAAATTTTACAAAAAGGGAGTTAAAGTTCTTGTAATCATTCTAATAGGATTTTTAAGTGGTGCCTT
AGGAAGTTTCGTAACATTACAACTTTATCAAAAACAAGGAAATCAAGCTACAAATAATAATTCTGGCACTGTAACTCAAA
CATCATACAAGAATGAAAACTCAACTACTCAAGCAGTGAATAAAATTAAGGATGCTGTTGTATCAGTCATTACTTACTCT
GCTAATAAACAAAGTAGTGTATTTGGAACCGAAGAATCAAATTCTGATACGGATAATCAACAGATTGCAAGTGAAGGATC
AGGTGTCATCTATAGAAAGAACGAAAATGATGCTTATATTGTAACAAATACTCACGTTATTAACGGAGCTTCAAAAGTTG
ATATCCGCTTAGCTGATGGTACAAAAGTTCCTGGTGAAATTATCGGATCGGATACCTTCTCTGATATTGCTGTCGTAAAA
ATTTCTTCAGAAAAAGTTACAACAGTGGCAGAATTTGGTGATTCAAGCCAACTTAATGTTGGAGAAACAGCGATTGCTAT
TGGTAGTCCTTTAGGTTCAGAATATGCTAATACAGTTACACAGGGAATCATCTCAAGTCTTAATCGAAATGTTTCTCTAA
AATCTGAAGATGGTCAAGCTATTTCAACAAAAGCCATTCAAACAGATACGGCCATTAACCCTGGTAACTCTGGTGGTCCG
CTTGTAAATATTCAAGGACAAGTAATTGGTATTACATCAAGTAAGATTGCAAGTAATGGTGGAACATCTGTGGAAGGTCT
TGGTTTTGCAATTCCTTCAAACGATGTACAAAATATTATTAAACAGCTTGAAAGTGATGGTAAAGTGACTCGTCCTGCTC
TTGGAATCCAAATGGTCAATCTATCTAACGTTGGAGCTAATGATCTTAGAAAACTAAACATTCCAAGTGGCCTCACTTCA
GGGGTAGTTGTTCGATCTGTTCAAAGTAATATGCCTGCAAATGGACATCTTCAAAAATACGATGTCATTACTAAAGTTGA
CGACAAAGAGATTACTTCATCAACAGACTTACAATATGCTCTTTACAACCATGCTATTGGAGACACTATAAAAATAACCT
ACTACCGTAATGGTAAGGAGGAAACAACCTCTATAAAACTAGATAAGAATTCTGGTGATTTGGAACGTTAA

Domains

Predicted by InterproScan.

• Trypsin-like peptidase domain (Trypsin_2) (106-251)

• PDZ domain (PDZ_2) (292-387)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus mitis NCTC 12261	83.544	99.747	0.833
htrA	Streptococcus pneumoniae Rx1	82.785	99.747	0.826
htrA	Streptococcus pneumoniae D39	82.785	99.747	0.826
htrA	Streptococcus pneumoniae R6	82.785	99.747	0.826
htrA	Streptococcus pneumoniae TIGR4	82.785	99.747	0.826
htrA	Streptococcus gordonii str. Challis substr. CH1	65.578	100	0.659
htrA	Streptococcus mutans UA159	53.435	99.242	0.53