Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   M2901_RS04935 Genome accession   NZ_CP097072
Coordinates   1004773..1006026 (+) Length   417 a.a.
NCBI ID   WP_248856243.1    Uniprot ID   -
Organism   Vagococcus lutrae strain AT03     
Function   facilitate localization of RecA (predicted from homology)   
Homologous recombination

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
ICE 977385..1028507 1004773..1006026 within 0


Gene organization within MGE regions


Location: 977385..1028507
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  M2901_RS04795 (M2901_04795) tsaE 977862..978344 (+) 483 WP_248848422.1 tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE -
  M2901_RS04800 (M2901_04800) - 978486..980939 (+) 2454 WP_248856231.1 5'-nucleotidase C-terminal domain-containing protein -
  M2901_RS04805 (M2901_04805) - 981114..981914 (+) 801 WP_248856232.1 CAP domain-containing protein -
  M2901_RS04810 (M2901_04810) - 981958..982494 (-) 537 WP_202585342.1 3'-5' exonuclease -
  M2901_RS04815 (M2901_04815) - 982491..983264 (-) 774 WP_248856233.1 exodeoxyribonuclease III -
  M2901_RS04820 (M2901_04820) murB 983444..984346 (+) 903 WP_023605838.1 UDP-N-acetylmuramate dehydrogenase -
  M2901_RS04825 (M2901_04825) - 984383..985390 (-) 1008 WP_248856234.1 acryloyl-CoA reductase -
  M2901_RS04830 (M2901_04830) - 985572..986114 (+) 543 WP_248856235.1 XRE family transcriptional regulator -
  M2901_RS04835 (M2901_04835) - 986133..987221 (+) 1089 WP_126762911.1 ABC transporter ATP-binding protein -
  M2901_RS04840 (M2901_04840) - 987233..988069 (+) 837 WP_023605842.1 ABC transporter permease -
  M2901_RS04845 (M2901_04845) - 988041..988868 (+) 828 WP_023605843.1 ABC transporter permease -
  M2901_RS04850 (M2901_04850) - 988865..989938 (+) 1074 WP_023605844.1 ABC transporter substrate-binding protein -
  M2901_RS04855 (M2901_04855) ispE 990066..990923 (+) 858 WP_248853046.1 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase -
  M2901_RS04860 (M2901_04860) - 991001..991483 (+) 483 WP_222317002.1 PTS glucose transporter subunit IIA -
  M2901_RS04865 (M2901_04865) - 991539..992477 (-) 939 WP_202585338.1 metal ABC transporter substrate-binding protein -
  M2901_RS04870 (M2901_04870) - 992474..993328 (-) 855 WP_023605848.1 metal ABC transporter permease -
  M2901_RS04875 (M2901_04875) - 993312..994064 (-) 753 WP_023605849.1 metal ABC transporter ATP-binding protein -
  M2901_RS04880 (M2901_04880) - 994249..994932 (+) 684 WP_023605850.1 metal ABC transporter ATP-binding protein -
  M2901_RS04885 (M2901_04885) - 994905..995732 (+) 828 WP_248856236.1 metal ABC transporter permease -
  M2901_RS04890 (M2901_04890) purR 995894..996721 (+) 828 WP_222317005.1 pur operon repressor -
  M2901_RS04895 (M2901_04895) glmU 996737..998110 (+) 1374 WP_248856237.1 bifunctional UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase GlmU -
  M2901_RS04900 (M2901_04900) - 998205..999176 (+) 972 WP_023605854.1 ribose-phosphate diphosphokinase -
  M2901_RS04905 (M2901_04905) mscL 999220..999663 (-) 444 WP_248856238.1 large conductance mechanosensitive channel protein MscL -
  M2901_RS04910 (M2901_04910) - 999868..1001139 (+) 1272 WP_023605856.1 pitrilysin family protein -
  M2901_RS04915 (M2901_04915) - 1001129..1002430 (+) 1302 WP_248856239.1 pitrilysin family protein -
  M2901_RS04920 (M2901_04920) - 1002433..1003158 (+) 726 WP_248856240.1 SDR family oxidoreductase -
  M2901_RS04925 (M2901_04925) - 1003183..1004031 (+) 849 WP_248856241.1 RodZ domain-containing protein -
  M2901_RS04930 (M2901_04930) pgsA 1004055..1004633 (+) 579 WP_248856242.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  M2901_RS04935 (M2901_04935) cinA 1004773..1006026 (+) 1254 WP_248856243.1 competence/damage-inducible protein A Machinery gene
  M2901_RS04940 (M2901_04940) recA 1006112..1007149 (+) 1038 WP_023605862.1 recombinase RecA Machinery gene
  M2901_RS04945 (M2901_04945) rny 1007369..1008928 (+) 1560 WP_126762880.1 ribonuclease Y -
  M2901_RS04950 (M2901_04950) - 1009210..1010427 (-) 1218 WP_001291561.1 tyrosine-type recombinase/integrase -
  M2901_RS04955 (M2901_04955) - 1010509..1010712 (-) 204 WP_000814511.1 excisionase -
  M2901_RS04960 (M2901_04960) - 1010696..1010947 (+) 252 WP_001845478.1 hypothetical protein -
  M2901_RS10120 - 1010981..1011109 (+) 129 WP_000301356.1 hypothetical protein -
  M2901_RS04965 (M2901_04965) - 1011173..1011403 (-) 231 WP_000857133.1 helix-turn-helix domain-containing protein -
  M2901_RS04970 (M2901_04970) - 1011400..1011822 (-) 423 WP_000804885.1 sigma-70 family RNA polymerase sigma factor -
  M2901_RS04975 (M2901_04975) - 1012375..1012680 (+) 306 WP_049532578.1 helix-turn-helix domain-containing protein -
  M2901_RS04980 (M2901_04980) - 1012740..1012907 (-) 168 WP_000336323.1 cysteine-rich KTR domain-containing protein -
  M2901_RS04985 (M2901_04985) tet(M) 1013026..1014945 (-) 1920 WP_000691736.1 tetracycline resistance ribosomal protection protein Tet(M) -
  M2901_RS04990 (M2901_04990) - 1014961..1015077 (-) 117 WP_001814923.1 tetracycline resistance determinant leader peptide -
  M2901_RS04995 (M2901_04995) - 1015322..1016254 (-) 933 WP_001224318.1 conjugal transfer protein -
  M2901_RS05000 (M2901_05000) - 1016251..1017252 (-) 1002 WP_000769868.1 bifunctional lysozyme/C40 family peptidase -
  M2901_RS05005 (M2901_05005) - 1017249..1019426 (-) 2178 WP_000804748.1 membrane protein -
  M2901_RS05010 (M2901_05010) - 1019429..1021876 (-) 2448 WP_000331160.1 ATP-binding protein -
  M2901_RS05015 (M2901_05015) - 1021860..1022252 (-) 393 WP_248856244.1 conjugal transfer protein -
  M2901_RS05020 (M2901_05020) - 1022341..1022838 (-) 498 WP_248856245.1 antirestriction protein ArdA -
  M2901_RS05025 (M2901_05025) - 1022955..1023176 (-) 222 WP_001009056.1 hypothetical protein -
  M2901_RS05030 (M2901_05030) mobT 1023219..1024424 (-) 1206 WP_000398284.1 MobT family relaxase -
  M2901_RS05035 (M2901_05035) - 1024447..1024599 (-) 153 WP_031764745.1 hypothetical protein -
  M2901_RS05040 (M2901_05040) - 1024602..1025987 (-) 1386 WP_000813488.1 FtsK/SpoIIIE domain-containing protein -
  M2901_RS05045 (M2901_05045) - 1026016..1026402 (-) 387 WP_000985015.1 YdcP family protein -
  M2901_RS05050 (M2901_05050) - 1026418..1026732 (-) 315 WP_000420682.1 YdcP family protein -
  M2901_RS05055 (M2901_05055) - 1027119..1027982 (+) 864 WP_126762878.1 alpha/beta fold hydrolase -

Sequence

Protein


Download         Length: 417 a.a.        Molecular weight: 45929.14 Da        Isoelectric Point: 4.5989

>NTDB_id=686933 M2901_RS04935 WP_248856243.1 1004773..1006026(+) (cinA) [Vagococcus lutrae strain AT03]
MRAEIIAVGTELLIGQVVNTNATFLSEELVGIGYDIYYHSVVGDNPERLKELIGQASRRSELIVLCGGLGPTEDDLTRDV
LADYLKEPMVLDPEGYDKIATYMTRSGREMTENNRRQALTIQGGQAIPNDTGLAVGTFYQAETTSYLVLPGPPRELKPMF
YHHVIPLLKQQLPQTDQLYSRVLRFFGIGESQLVLELETLIHEQTNPTIAPYAGETEVRLRLTVKATDETTANEMLDEME
EKIMSQVGDYFYGYGEENSLIKETVKALKAAKQTVASAESLTAGMFMSALGDVPGVSSVFNGGFVTYTNEMKRCLLKIDS
ALLAQHGAVSEACACAMAEQARVLTKSDYGVALTGVAGPDKSEGEPVGSVWIGLSSATSGTQAYHFQLQRDRQYIRQSAM
MRAMDLLRRQVIEENHD

Nucleotide


Download         Length: 1254 bp        

>NTDB_id=686933 M2901_RS04935 WP_248856243.1 1004773..1006026(+) (cinA) [Vagococcus lutrae strain AT03]
ATGCGAGCAGAAATTATCGCAGTGGGTACGGAGCTATTAATTGGCCAAGTGGTTAATACCAATGCGACTTTTTTATCAGA
AGAATTAGTGGGGATTGGTTATGATATTTATTATCACAGTGTGGTAGGGGATAACCCAGAGCGTTTAAAAGAGTTAATTG
GACAAGCCTCTCGGAGAAGTGAATTGATTGTGTTGTGTGGGGGGTTAGGACCAACAGAAGATGATTTAACGCGAGATGTG
TTAGCTGATTATTTAAAAGAGCCGATGGTGTTAGATCCAGAGGGTTACGATAAAATTGCTACCTATATGACACGGTCTGG
TCGCGAGATGACGGAAAATAATCGTAGGCAAGCGTTAACGATTCAAGGAGGTCAAGCGATACCGAATGATACAGGCTTGG
CAGTCGGGACTTTTTATCAAGCTGAGACGACGAGTTATTTAGTCTTACCAGGACCGCCGCGTGAGTTAAAACCGATGTTT
TATCATCATGTTATCCCATTGTTAAAGCAGCAGTTACCTCAAACCGACCAACTGTATTCTCGTGTATTACGCTTTTTTGG
TATCGGGGAGTCACAGTTAGTTTTAGAATTAGAAACATTAATTCACGAGCAAACGAATCCGACCATTGCGCCATACGCAG
GTGAAACAGAAGTTCGTTTACGACTGACAGTCAAAGCAACAGATGAGACGACAGCAAATGAGATGCTAGATGAGATGGAA
GAAAAAATTATGTCTCAAGTGGGAGATTACTTCTATGGTTATGGGGAAGAAAATAGTTTGATTAAAGAAACTGTCAAGGC
CTTAAAAGCCGCGAAGCAAACGGTCGCCTCGGCCGAAAGTTTGACTGCTGGGATGTTTATGAGTGCATTGGGAGACGTTC
CCGGTGTTTCTAGTGTCTTTAATGGTGGCTTTGTCACATATACGAATGAGATGAAACGTTGCTTATTAAAGATTGATTCA
GCTTTGCTTGCTCAACACGGGGCTGTTAGTGAGGCGTGTGCGTGTGCGATGGCAGAACAGGCTCGTGTGTTAACAAAGAG
TGACTATGGTGTAGCGTTAACAGGCGTAGCAGGTCCAGATAAAAGTGAGGGTGAGCCTGTAGGAAGTGTGTGGATTGGCC
TTTCTTCTGCGACAAGTGGGACACAGGCTTATCATTTTCAACTTCAGCGAGACCGTCAATATATTCGGCAAAGTGCCATG
ATGCGCGCAATGGACTTATTACGTCGTCAAGTGATAGAAGAAAATCACGACTAA

Domains

Predicted by InterproScan.

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)

Damage-inducible protein CinA KH domain (CinA_KH)

(180-253)

Competence-damaged protein (CinA)

(259-410)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus pneumoniae TIGR4

49.645

100

0.504
  cinA Streptococcus pneumoniae R6

49.173

100

0.499
  cinA Streptococcus pneumoniae Rx1

49.173

100

0.499
  cinA Streptococcus mitis NCTC 12261

48.936

100

0.496
  cinA Streptococcus mitis SK321

48.936

100

0.496
  cinA Streptococcus pneumoniae D39

48.936

100

0.496
  cinA Streptococcus mutans UA159

48.21

100

0.484
  cinA Bacillus subtilis subsp. subtilis str. 168

46.078

97.842

0.451
  cinA Streptococcus suis isolate S10

42.579

98.561

0.42