Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   MRL80_RS12445 Genome accession   NZ_CP095333
Coordinates   2589189..2590433 (-) Length   414 a.a.
NCBI ID   WP_131639182.1    Uniprot ID   -
Organism   Enterococcus faecalis strain 19CA02SA02     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 2584189..2595433
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MRL80_RS12425 (MRL80_12360) - 2584659..2585045 (-) 387 WP_002359008.1 YlbF family regulator -
  MRL80_RS12430 (MRL80_12365) - 2585119..2585916 (-) 798 WP_002354864.1 TIGR00282 family metallophosphoesterase -
  MRL80_RS12435 (MRL80_12370) rny 2586076..2587632 (-) 1557 WP_002354863.1 ribonuclease Y -
  MRL80_RS12440 (MRL80_12375) recA 2588029..2589075 (-) 1047 WP_002354860.1 recombinase RecA Machinery gene
  MRL80_RS12445 (MRL80_12380) cinA 2589189..2590433 (-) 1245 WP_131639182.1 competence/damage-inducible protein A Machinery gene
  MRL80_RS12450 (MRL80_12385) - 2590625..2591830 (+) 1206 WP_002360981.1 hypothetical protein -
  MRL80_RS12455 (MRL80_12390) - 2591908..2592537 (-) 630 WP_002354854.1 NAD(P)-dependent oxidoreductase -
  MRL80_RS12460 (MRL80_12395) - 2592596..2593021 (-) 426 WP_002383201.1 Rrf2 family transcriptional regulator -
  MRL80_RS12465 (MRL80_12400) - 2593110..2593493 (-) 384 WP_002354850.1 YccF domain-containing protein -
  MRL80_RS12470 (MRL80_12405) - 2593657..2594448 (+) 792 WP_002367471.1 hypothetical protein -

Sequence

Protein


Download         Length: 414 a.a.        Molecular weight: 45194.23 Da        Isoelectric Point: 4.5825

>NTDB_id=676411 MRL80_RS12445 WP_131639182.1 2589189..2590433(-) (cinA) [Enterococcus faecalis strain 19CA02SA02]
MKAEIIAVGTELLLGQVVNTNATFLSEELAALGIDVYYQTVVGDNGGRLETLLTEAEQRSDLIVLCGGLGPTEDDLTKQV
VAQHLHKSLVEDQEGLNRLHQFFQQSKRPMTENNLRQVLAIEGGQVLQNPTGLAVGSFVTEGTTSYLLLPGPPNELIPMF
QQAARPLLIDAFPQEEQLISRVLRFYGIGESQLVTEIQSLIAHQTNPTIAPYAKPNEVTLRLTVKTKDLVAGEELLTATE
EKVLAKVGDYFYGYGDDNSLAKVTVDLLLQNGQTVTAAESLTAGLFQSTLGEIAGASKIFKGGFVTYSQETKENFLGISH
ELLEEHGTVSEACAKEMAEKARQLAKSNYGLSFTGVAGDPIEGQPTGTVWIGLAEEGQPTVAECFHFNRDRNYIRQSAVM
RGLDLLRRRIINEK

Nucleotide


Download         Length: 1245 bp        

>NTDB_id=676411 MRL80_RS12445 WP_131639182.1 2589189..2590433(-) (cinA) [Enterococcus faecalis strain 19CA02SA02]
ATGAAAGCAGAAATCATTGCAGTCGGAACAGAGTTATTACTGGGACAAGTAGTGAATACCAACGCCACCTTTTTATCAGA
AGAGTTAGCTGCGCTAGGTATCGATGTTTACTATCAGACCGTTGTTGGCGATAACGGCGGCCGCTTAGAAACGCTACTAA
CAGAAGCAGAACAAAGAAGTGATTTAATTGTCCTTTGTGGAGGGCTAGGACCTACAGAAGACGATTTAACCAAGCAAGTT
GTCGCACAACATCTCCATAAATCATTAGTAGAAGATCAAGAAGGATTGAACCGCTTGCACCAGTTTTTCCAACAGTCTAA
GCGGCCAATGACGGAAAATAATCTACGACAAGTGTTAGCCATTGAAGGTGGACAAGTTCTTCAAAACCCGACAGGATTAG
CGGTTGGTTCTTTCGTAACAGAAGGCACAACAAGCTATTTGCTCTTACCAGGACCACCCAATGAATTAATTCCGATGTTC
CAACAAGCGGCACGACCTTTATTGATTGATGCGTTTCCACAAGAAGAACAATTGATTTCAAGAGTCTTGCGTTTTTATGG
CATTGGTGAATCACAGCTGGTGACCGAGATTCAATCGTTGATTGCGCACCAAACGAATCCAACCATTGCGCCTTATGCTA
AGCCTAATGAAGTGACACTTCGTTTAACAGTTAAAACAAAAGACTTAGTAGCTGGCGAAGAATTATTAACAGCGACGGAA
GAAAAGGTTTTAGCTAAAGTGGGAGACTATTTTTATGGGTATGGGGATGACAATAGTTTAGCCAAGGTAACAGTGGATTT
GTTATTACAAAACGGACAAACCGTCACGGCTGCTGAGAGCCTCACCGCTGGCCTATTCCAAAGTACACTGGGGGAAATTG
CGGGTGCTTCGAAGATTTTTAAGGGAGGCTTCGTGACGTATTCGCAAGAAACAAAAGAGAACTTTTTAGGAATTTCTCAT
GAACTTTTAGAAGAGCATGGCACGGTAAGTGAAGCGTGTGCCAAAGAAATGGCAGAGAAAGCGCGTCAGTTAGCTAAATC
TAACTATGGTTTATCATTTACTGGGGTCGCTGGTGACCCAATCGAAGGTCAACCGACAGGCACTGTTTGGATTGGGCTGG
CGGAAGAAGGCCAACCAACCGTTGCAGAATGTTTCCATTTTAACCGTGACCGAAATTATATTAGACAGAGTGCGGTTATG
CGAGGGTTAGATCTTTTGCGGCGCCGAATCATTAATGAAAAATAA

Domains

Predicted by InterproScan.

Probable molybdopterin binding domain (MoCF_biosynth)

(5-168)

Competence-damaged protein (CinA)

(258-409)

Damage-inducible protein CinA KH domain (CinA_KH)

(180-253)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mutans UA159

52.392

100

0.529
  cinA Streptococcus mitis SK321

51.415

100

0.527
  cinA Streptococcus mitis NCTC 12261

51.179

100

0.524
  cinA Streptococcus pneumoniae TIGR4

50.472

100

0.517
  cinA Streptococcus pneumoniae D39

50.236

100

0.514
  cinA Streptococcus pneumoniae R6

50

100

0.512
  cinA Streptococcus pneumoniae Rx1

50

100

0.512
  cinA Bacillus subtilis subsp. subtilis str. 168

48.522

98.068

0.476
  cinA Streptococcus suis isolate S10

44.039

99.275

0.437