Detailed information NTG0668138

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: MP387_RS09120
• Genome accession: NZ_CP094226
• Coordinates: 1874512..1875705 (+)
• Length: 397 a.a.
• NCBI ID: WP_242746621.1
• Uniprot ID: -
• Organism: Streptococcus oralis strain 1648
• Function: repress competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1869512..1880705

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MP387_RS09080 (MP387_09080)	-	1870571..1871113 (+)	543	WP_000665080.1	TetR-like C-terminal domain-containing protein	-
MP387_RS09095 (MP387_09095)	comE	1871351..1872103 (-)	753	WP_000866079.1	competence system response regulator transcription factor ComE	Regulator
MP387_RS09100 (MP387_09100)	comD	1872100..1873419 (-)	1320	WP_242746613.1	competence system sensor histidine kinase ComD	Regulator
MP387_RS09105 (MP387_09105)	comC/comC1	1873440..1873565 (-)	126	WP_008282505.1	competence-stimulating peptide ComC	Regulator
MP387_RS09115 (MP387_09115)	rlmH	1873847..1874326 (-)	480	WP_242746617.1	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	-
MP387_RS09120 (MP387_09120)	htrA	1874512..1875705 (+)	1194	WP_242746621.1	S1C family serine protease	Regulator
MP387_RS09125 (MP387_09125)	spo0J	1875763..1876521 (+)	759	WP_242746624.1	ParB/RepB/Spo0J family partition protein	Regulator

Sequence

Protein

• Length: 397 a.a.
• Molecular weight: 41938.75 Da
• Isoelectric Point: 6.3586

>NTDB_id=668138 MP387_RS09120 WP_242746621.1 1874512..1875705(+) (htrA) [Streptococcus oralis strain 1648]
MKHLQKFYKKGVKVLVIILIGFLSGALGSFVTLQLYQKQGNQATNNNSGTVTQTSYKNENSTTQAVNKVKDAVVSIITYS
SNSRQSSVFNADETNSDSDNQQIASEGSGVIYKKDDKDAYLVTNTHVINGASKVDIRLADGTKVPGEIVGSDTFSDIAVV
KISSEKVTTVAEFGDSSQLSVGETAIAIGSPLGSEYANTVTQGIISSLNRNVSLKSEDGQAISTKAIQTDTAINPGNSGG
PLVNIQGQVIGITSSKIASNGGTSVEGLGFAIPSNDAQNIIKQLESDGKVTRPALGIQMVNLSNVGASDLRKLNIPSGLT
SGVVVRSVQNNMPANGHLQKYDVITKVDDKEIASSTDLQHALYNHAIGDTIKVTYYRNGKEETTSIKLDKNSGDLES

Nucleotide

• Length: 1194 bp

>NTDB_id=668138 MP387_RS09120 WP_242746621.1 1874512..1875705(+) (htrA) [Streptococcus oralis strain 1648]
ATGAAACACTTACAAAAATTTTACAAAAAAGGAGTTAAAGTTCTTGTAATCATTCTAATCGGATTTTTAAGTGGTGCCTT
AGGAAGTTTCGTAACATTACAACTTTATCAAAAACAAGGAAATCAAGCTACAAATAACAATTCTGGCACTGTCACTCAAA
CATCCTATAAGAATGAAAATTCAACCACTCAAGCAGTAAATAAAGTTAAGGATGCTGTTGTCTCAATCATTACTTATTCT
TCTAATAGTAGACAAAGTAGTGTATTTAATGCTGATGAAACTAATTCTGATTCAGACAATCAACAAATCGCAAGTGAGGG
ATCAGGTGTTATCTATAAAAAGGATGATAAAGATGCCTATCTTGTAACTAATACTCACGTTATCAATGGAGCTTCAAAAG
TTGATATCCGCTTAGCAGATGGTACTAAGGTTCCTGGTGAAATTGTCGGATCTGATACCTTCTCTGATATTGCTGTCGTT
AAAATTTCTTCAGAAAAAGTTACAACAGTAGCAGAATTTGGGGATTCAAGTCAACTTAGTGTTGGAGAAACAGCGATTGC
TATCGGTAGTCCTTTAGGTTCAGAATATGCTAATACAGTTACACAGGGGATTATTTCAAGTCTTAATCGAAATGTTTCTC
TAAAATCTGAAGATGGTCAAGCTATTTCAACAAAAGCCATTCAAACAGATACAGCTATTAACCCTGGTAACTCTGGTGGT
CCACTTGTAAACATCCAAGGACAAGTAATTGGTATAACATCAAGTAAAATTGCAAGTAATGGTGGAACATCTGTAGAAGG
TCTTGGTTTTGCAATTCCTTCAAACGATGCACAAAATATCATTAAACAGCTTGAAAGTGATGGTAAAGTGACTCGTCCAG
CTCTTGGAATTCAAATGGTCAATCTATCAAATGTTGGAGCTAGTGATCTTAGAAAACTTAACATTCCAAGTGGCCTCACT
TCAGGTGTAGTTGTTCGATCTGTTCAAAACAATATGCCAGCAAATGGACATCTTCAAAAATACGATGTCATTACCAAAGT
TGACGATAAAGAGATTGCTTCATCAACAGACCTACAACACGCTCTTTACAATCATGCTATCGGAGATACTATCAAAGTAA
CCTACTACCGTAACGGTAAGGAGGAAACAACCTCAATTAAACTAGATAAGAATTCTGGTGATTTAGAGTCTTAA

Domains

Predicted by InterproScan.

• Trypsin-like peptidase domain (Trypsin_2) (107-252)

• PDZ domain (PDZ_2) (293-388)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus mitis NCTC 12261	84.131	100	0.841
htrA	Streptococcus pneumoniae Rx1	83.375	100	0.834
htrA	Streptococcus pneumoniae D39	83.375	100	0.834
htrA	Streptococcus pneumoniae R6	83.375	100	0.834
htrA	Streptococcus pneumoniae TIGR4	83.375	100	0.834
htrA	Streptococcus gordonii str. Challis substr. CH1	66.584	100	0.673
htrA	Streptococcus mutans UA159	54.707	98.992	0.542