Detailed information    

insolico Bioinformatically predicted

Overview

Name   comD   Type   Regulator
Locus tag   MP387_RS09100 Genome accession   NZ_CP094226
Coordinates   1872100..1873419 (-) Length   439 a.a.
NCBI ID   WP_242746613.1    Uniprot ID   -
Organism   Streptococcus oralis strain 1648     
Function   phosphorylation of ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 1867100..1878419
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MP387_RS09075 (MP387_09075) - 1867788..1870442 (-) 2655 WP_242746611.1 YhgE/Pip domain-containing protein -
  MP387_RS09080 (MP387_09080) - 1870571..1871113 (+) 543 WP_000665080.1 TetR-like C-terminal domain-containing protein -
  MP387_RS09095 (MP387_09095) comE 1871351..1872103 (-) 753 WP_000866079.1 competence system response regulator transcription factor ComE Regulator
  MP387_RS09100 (MP387_09100) comD 1872100..1873419 (-) 1320 WP_242746613.1 competence system sensor histidine kinase ComD Regulator
  MP387_RS09105 (MP387_09105) comC/comC1 1873440..1873565 (-) 126 WP_008282505.1 competence-stimulating peptide ComC Regulator
  MP387_RS09115 (MP387_09115) rlmH 1873847..1874326 (-) 480 WP_242746617.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  MP387_RS09120 (MP387_09120) htrA 1874512..1875705 (+) 1194 WP_242746621.1 S1C family serine protease Regulator
  MP387_RS09125 (MP387_09125) spo0J 1875763..1876521 (+) 759 WP_242746624.1 ParB/RepB/Spo0J family partition protein Regulator

Sequence

Protein


Download         Length: 439 a.a.        Molecular weight: 50941.91 Da        Isoelectric Point: 6.6370

>NTDB_id=668136 MP387_RS09100 WP_242746613.1 1872100..1873419(-) (comD) [Streptococcus oralis strain 1648]
MSLLGFGIVILHIFILTISYELICKVTKKERYLFIACIFVYQSVAEFFFDFISLAGLGIEKFIFPFILYTSIVVLKKYDK
HKGMFISLLLSLLYHSTHTFLSVTLSSITGDAFVIEHEVMFYLGVLLLTYFIIKKIITYFHLELTYFDKDYLYPFLKKVI
VAFFGLHILLFISDIVSTTHHLNSFGSILSTIVFICLLLILFAMNSHKVQIEKEIALKQKKFEQKHLQTYTDEIVELYNE
IRGFRHDYAGMLVSMQMAIDSGNLQEINRVYNEVLVKANQKLRSEKYTYFDLNNIEDSALRSLIAQSIVYARKNDVEFTL
EVKDIITRLSIDLLDLVRIMSILLNNAVEGAADSYLKQMEVAVIKMDFETVIVIQNSCKITMTPSEDLFALGFSTKGRNR
GLGLNNVKEILDKYDNIILETEMEDNTFRQIIRFKREFE

Nucleotide


Download         Length: 1320 bp        

>NTDB_id=668136 MP387_RS09100 WP_242746613.1 1872100..1873419(-) (comD) [Streptococcus oralis strain 1648]
ATGAGTTTATTAGGATTTGGAATAGTTATTCTTCATATTTTTATTTTAACAATAAGCTATGAATTAATTTGTAAAGTAAC
TAAAAAAGAAAGATATTTATTTATAGCTTGTATATTTGTATATCAGTCTGTAGCTGAATTTTTCTTTGACTTTATTTCAT
TAGCTGGGTTAGGGATTGAAAAGTTTATATTTCCTTTTATTCTATATACTTCTATAGTAGTTTTAAAGAAATATGATAAG
CATAAAGGAATGTTTATCAGTTTACTATTGTCTTTATTATATCATAGTACACACACTTTTTTATCAGTAACCCTATCCTC
TATAACAGGTGATGCTTTTGTGATAGAACATGAAGTGATGTTTTATTTAGGAGTACTATTACTAACATATTTTATTATTA
AAAAAATTATTACTTATTTCCATTTAGAACTTACTTATTTTGATAAAGATTATCTGTATCCTTTTTTAAAAAAAGTAATA
GTTGCTTTCTTTGGTTTACATATCTTATTGTTTATTTCAGATATAGTAAGTACAACTCATCATTTAAATAGCTTCGGAAG
TATTTTATCAACCATTGTTTTTATTTGCTTGTTATTGATTTTATTTGCAATGAATTCTCACAAGGTTCAAATTGAAAAAG
AGATTGCTCTAAAACAAAAGAAATTTGAACAAAAGCATTTACAGACTTATACTGATGAAATTGTGGAGTTGTATAATGAA
ATTCGAGGTTTTCGTCATGACTATGCAGGGATGCTTGTCAGCATGCAAATGGCGATTGACAGTGGAAATTTACAAGAAAT
TAACAGGGTTTACAATGAAGTCTTAGTAAAAGCAAATCAGAAATTGAGATCAGAAAAATATACTTACTTTGATTTAAATA
ATATAGAAGATTCTGCTTTACGAAGTTTAATTGCTCAATCGATTGTCTATGCACGAAAAAATGATGTAGAGTTTACATTG
GAAGTAAAGGATATCATTACTAGACTGTCAATAGATTTACTTGATCTTGTTCGTATCATGAGCATTTTATTAAACAATGC
TGTTGAAGGTGCTGCAGATAGTTATTTGAAACAAATGGAAGTTGCAGTCATTAAAATGGATTTTGAAACAGTTATAGTTA
TCCAGAATTCATGCAAAATCACTATGACGCCTTCAGAGGACCTATTTGCCTTAGGTTTCTCTACTAAGGGAAGAAATAGA
GGTCTAGGACTTAATAATGTCAAAGAGATTTTAGATAAGTATGACAACATTATTTTAGAAACAGAGATGGAAGACAACAC
ATTTAGACAAATTATTAGATTTAAGAGGGAATTCGAATGA

Domains

Predicted by InterproScan.

GHKL domain (HATPase_c_5)

(333-432)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comD Streptococcus mitis NCTC 12261

75.283

100

0.756
  comD/comD2 Streptococcus pneumoniae TIGR4

74.603

100

0.749
  comD Streptococcus mitis SK321

74.376

100

0.747
  comD/comD1 Streptococcus pneumoniae R6

73.923

100

0.743
  comD/comD1 Streptococcus pneumoniae Rx1

73.923

100

0.743
  comD/comD1 Streptococcus pneumoniae D39

73.923

100

0.743
  comD/comD2 Streptococcus gordonii strain NCTC7865

50.798

85.649

0.435
  comD/comD1 Streptococcus gordonii str. Challis substr. CH1

50.267

85.194

0.428

Multiple sequence alignment