Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   ML603_RS09500 Genome accession   NZ_CP092887
Coordinates   1927768..1929039 (-) Length   423 a.a.
NCBI ID   WP_241067223.1    Uniprot ID   -
Organism   Streptococcus dysgalactiae subsp. equisimilis strain Karl     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 1922768..1934039
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ML603_RS09470 (ML603_09470) - 1922824..1924386 (-) 1563 WP_241067221.1 DUF2079 domain-containing protein -
  ML603_RS09475 (ML603_09475) - 1924721..1925026 (-) 306 WP_143928077.1 DUF1292 domain-containing protein -
  ML603_RS09480 (ML603_09480) ruvX 1925037..1925456 (-) 420 WP_003053103.1 Holliday junction resolvase RuvX -
  ML603_RS09485 (ML603_09485) - 1925453..1925722 (-) 270 WP_003045720.1 IreB family regulatory phosphoprotein -
  ML603_RS09490 (ML603_09490) spx 1925834..1926232 (-) 399 WP_003053105.1 transcriptional regulator Spx -
  ML603_RS09495 (ML603_09495) recA 1926527..1927663 (-) 1137 WP_241067222.1 recombinase RecA Machinery gene
  ML603_RS09500 (ML603_09500) cinA 1927768..1929039 (-) 1272 WP_241067223.1 competence/damage-inducible protein A Machinery gene
  ML603_RS09505 (ML603_09505) - 1929163..1929516 (-) 354 WP_241067224.1 VOC family protein -
  ML603_RS09510 (ML603_09510) - 1929519..1930091 (-) 573 WP_138126794.1 DNA-3-methyladenine glycosylase I -
  ML603_RS09515 (ML603_09515) ruvA 1930101..1930694 (-) 594 WP_143928080.1 Holliday junction branch migration protein RuvA -
  ML603_RS09520 (ML603_09520) - 1930696..1931916 (-) 1221 WP_143928081.1 MFS transporter -
  ML603_RS09525 (ML603_09525) mutL 1931927..1933909 (-) 1983 WP_241067225.1 DNA mismatch repair endonuclease MutL -

Sequence

Protein


Download         Length: 423 a.a.        Molecular weight: 46031.49 Da        Isoelectric Point: 4.7069

>NTDB_id=660954 ML603_RS09500 WP_241067223.1 1927768..1929039(-) (cinA) [Streptococcus dysgalactiae subsp. equisimilis strain Karl]
MKAELITVGTEILTGQIVNTNAQFLSEKMAELGIDVYFQTAVGDNEERLLSVIATASQRSDLVILCGGIGPTEDDLTKQT
LAKYLNRDLVFEEQASQKLDDFYASRKESSRTANNAKQAQIIAGSSPLQNRTGLAVGGLITVNEVTYVVLPGPPSELKPM
VNEELLPLLSTQSRKLYSRVLRFFGIGESQLVTVLSDLIENQTDPTIAPYAKTGEVTLRLSTKAENQTLADTKLDPLEAQ
LLSRKTPDNQSLSDFLYGYREDNSLAREVFELLVKYDKTITAAESLTAGLFQSTLASFPGASQVFNGGFVTYSMEEKAKM
LGIPLEDLISHGVVSAYTAEKMAEQTRLLTGADIGVSLTGVAGPDMLEDQPVGTVFIGLATQNKVESMKVLIGGRSRSDV
RHIATLHAFNMVRKTLLKPENLL

Nucleotide


Download         Length: 1272 bp        

>NTDB_id=660954 ML603_RS09500 WP_241067223.1 1927768..1929039(-) (cinA) [Streptococcus dysgalactiae subsp. equisimilis strain Karl]
ATGAAAGCTGAACTGATTACAGTAGGTACCGAAATTTTGACTGGTCAAATTGTGAATACCAATGCTCAATTTCTGTCGGA
AAAAATGGCAGAGCTAGGTATTGATGTCTATTTTCAAACGGCTGTTGGGGATAACGAGGAGCGTTTACTTTCAGTGATTG
CAACTGCTAGTCAGCGGAGTGATTTGGTCATTTTATGCGGCGGTATTGGTCCCACGGAAGATGATTTAACCAAGCAGACT
TTAGCAAAATATCTTAATAGAGATTTGGTCTTTGAAGAACAAGCTAGTCAAAAATTGGACGATTTTTATGCTAGTCGTAA
AGAGTCATCTCGAACGGCAAATAATGCTAAGCAGGCTCAAATCATTGCTGGTTCAAGCCCTCTGCAAAATAGAACAGGAC
TTGCAGTGGGTGGCTTAATCACTGTTAATGAGGTGACTTATGTTGTTTTACCCGGGCCGCCAAGTGAATTAAAACCTATG
GTTAATGAGGAACTGCTTCCTCTTTTGTCCACACAATCTCGCAAACTTTATTCGAGAGTTTTACGATTTTTTGGGATTGG
TGAGAGTCAGCTGGTGACGGTCTTATCAGACCTTATTGAGAATCAAACTGACCCTACTATTGCACCTTATGCTAAAACTG
GTGAAGTGACCCTTCGTTTATCAACGAAAGCTGAAAATCAAACATTAGCAGATACGAAATTAGATCCACTAGAAGCGCAG
CTATTGTCGCGAAAAACTCCTGACAACCAGTCGTTATCAGATTTTCTTTATGGCTATAGGGAGGATAATTCCTTAGCGCG
TGAGGTATTTGAGCTCTTAGTAAAATATGATAAGACAATTACAGCAGCAGAAAGTCTAACCGCGGGATTATTTCAGTCAA
CTTTGGCGAGTTTTCCAGGAGCTTCTCAAGTATTCAATGGAGGCTTTGTAACTTATAGCATGGAAGAAAAAGCGAAAATG
CTAGGCATTCCTTTAGAGGATTTGATATCGCATGGAGTTGTTAGTGCTTATACGGCCGAGAAGATGGCGGAGCAAACACG
GTTATTGACTGGTGCTGATATTGGGGTAAGTTTAACAGGTGTTGCTGGACCAGATATGTTGGAGGACCAGCCTGTAGGTA
CAGTTTTCATTGGCCTTGCCACTCAAAATAAGGTAGAATCAATGAAGGTTTTAATCGGGGGACGGAGCCGCTCAGATGTG
CGTCATATTGCGACTTTACATGCTTTTAATATGGTCCGTAAAACTTTATTAAAACCTGAAAATTTGCTATAA

Domains

Predicted by InterproScan.

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)

Competence-damaged protein (CinA)

(263-416)

Damage-inducible protein CinA KH domain (CinA_KH)

(178-243)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mutans UA159

71.868

100

0.719
  cinA Streptococcus mitis SK321

70.264

98.582

0.693
  cinA Streptococcus mitis NCTC 12261

69.305

98.582

0.683
  cinA Streptococcus pneumoniae TIGR4

69.065

98.582

0.681
  cinA Streptococcus pneumoniae Rx1

69.065

98.582

0.681
  cinA Streptococcus pneumoniae R6

69.065

98.582

0.681
  cinA Streptococcus pneumoniae D39

68.825

98.582

0.678
  cinA Streptococcus suis isolate S10

53.125

98.345

0.522
  cinA Bacillus subtilis subsp. subtilis str. 168

45.455

98.818

0.449