Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   SMUNUM_RS10015 Genome accession   NZ_AP014571
Coordinates   2019317..2020573 (-) Length   418 a.a.
NCBI ID   WP_002270966.1    Uniprot ID   -
Organism   Streptococcus mutans LP13     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 2014317..2025573
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SMUNUM_RS09970 (SMNUM_1890) - 2014512..2014811 (-) 300 WP_002262384.1 DUF1292 domain-containing protein -
  SMUNUM_RS09975 (SMNUM_1891) ruvX 2014892..2015311 (-) 420 WP_002262385.1 Holliday junction resolvase RuvX -
  SMUNUM_RS09980 (SMNUM_1892) - 2015308..2015577 (-) 270 WP_002262386.1 IreB family regulatory phosphoprotein -
  SMUNUM_RS09985 (SMNUM_1894) brsR 2015745..2016178 (+) 434 Protein_1916 bacteriocin genes transcriptional regulator BrsR -
  SMUNUM_RS09990 (SMNUM_1895) brsM 2016191..2016637 (+) 447 WP_002262388.1 bacteriocin genes regulator BrsM Regulator
  SMUNUM_RS09995 - 2016628..2016840 (-) 213 WP_002262389.1 hypothetical protein -
  SMUNUM_RS10000 (SMNUM_1896) - 2016967..2017392 (-) 426 WP_002264551.1 hypothetical protein -
  SMUNUM_RS10005 (SMNUM_1897) spx 2017643..2018041 (-) 399 WP_002262391.1 transcriptional regulator Spx -
  SMUNUM_RS10010 (SMNUM_1898) recA 2018126..2019277 (-) 1152 WP_002262392.1 recombinase RecA Machinery gene
  SMUNUM_RS10015 (SMNUM_1899) cinA 2019317..2020573 (-) 1257 WP_002270966.1 competence/damage-inducible protein A Machinery gene
  SMUNUM_RS10020 (SMNUM_1900) - 2020722..2021282 (-) 561 WP_002268198.1 DNA-3-methyladenine glycosylase I -
  SMUNUM_RS10025 (SMNUM_1901) ruvA 2021364..2021957 (-) 594 WP_002266975.1 Holliday junction branch migration protein RuvA -
  SMUNUM_RS10030 (SMNUM_1902) mutL 2022144..2024099 (-) 1956 WP_019805529.1 DNA mismatch repair endonuclease MutL -
  SMUNUM_RS10035 - 2024324..2024602 (+) 279 Protein_1926 transposase -

Sequence

Protein


Download         Length: 418 a.a.        Molecular weight: 45704.48 Da        Isoelectric Point: 6.2714

>NTDB_id=66019 SMUNUM_RS10015 WP_002270966.1 2019317..2020573(-) (cinA) [Streptococcus mutans LP13]
MKSEIIAVGTEILTGQIVNTNSQFLSEKFAELGIDVYFQTAVGDNEERLLSVLKIAKERSDLIVLCGGLGPTEDDLTKQT
LAKFLKRELVFDKTAQERLDEFFASRPTSMRTPNNECQAQIIAGSQPLSNKTGLAVGGLLEADGVTYVVLPGPPSELKPM
VNKELLPYLSKTSEKLYSRVLRFFGIGESHLVTLLHDLIAEQTDPTIAPYAKTGEVTIRLSTKAHRQKEADSKLDKLEKK
IVTIDNLADYFYGYGEENSLPQVVFDLLKEKGKTITAAESLTAGLFQARLADFAGASDIFKGGFITYSIEEKARMLGIPF
EDLQLHGVVSAFTAEKMAERSRQLTQADLAVSLTGVAGPDSLEGQPAGTVFIGLSSSKRTMAIKVLIGGRSRSDVRYIAV
LHAFNLVRQTLLSHKNLV

Nucleotide


Download         Length: 1257 bp        

>NTDB_id=66019 SMUNUM_RS10015 WP_002270966.1 2019317..2020573(-) (cinA) [Streptococcus mutans LP13]
ATGAAATCTGAGATCATTGCTGTTGGAACAGAAATTTTAACAGGACAAATTGTTAATACTAATAGTCAATTTTTATCAGA
AAAATTCGCAGAATTAGGAATTGATGTTTATTTTCAAACAGCAGTTGGTGATAATGAAGAACGCCTTTTATCTGTTTTGA
AAATTGCAAAGGAACGTAGTGATTTAATCGTACTTTGTGGTGGTTTGGGACCAACAGAAGATGATTTAACAAAACAAACC
CTAGCAAAATTTTTGAAAAGAGAATTGGTATTTGATAAAACAGCTCAAGAACGTCTAGATGAATTTTTTGCATCACGTCC
AACATCTATGCGCACACCAAATAATGAATGTCAGGCGCAGATTATAGCAGGAAGTCAGCCTTTATCTAATAAAACAGGTT
TAGCAGTTGGGGGGCTTTTGGAGGCAGATGGAGTGACTTATGTTGTATTACCTGGTCCGCCTAGCGAATTGAAGCCTATG
GTTAACAAAGAGTTACTCCCTTATTTATCAAAAACTTCTGAGAAGCTTTATTCTCGTGTGTTACGCTTTTTTGGTATTGG
TGAGAGTCATCTAGTGACCTTGTTGCATGACTTAATAGCGGAGCAAACAGATCCCACAATTGCTCCTTATGCTAAGACAG
GCGAGGTAACAATACGTTTATCAACAAAAGCCCATAGGCAGAAAGAAGCAGATAGTAAGTTAGATAAGTTGGAAAAGAAA
ATTGTAACTATTGATAACTTGGCTGATTATTTTTATGGTTATGGTGAAGAAAATTCATTACCACAGGTTGTATTTGATCT
GCTTAAGGAAAAGGGTAAAACGATTACAGCAGCTGAAAGTTTAACAGCAGGCCTTTTTCAGGCAAGATTAGCAGATTTTG
CAGGAGCATCTGATATCTTTAAGGGAGGTTTTATAACTTACAGTATAGAAGAGAAGGCTAGAATGCTAGGTATTCCCTTT
GAAGATCTCCAACTTCATGGGGTTGTTAGTGCTTTTACTGCTGAAAAGATGGCAGAGCGCTCCCGCCAGCTGACTCAAGC
AGATTTGGCTGTTTCTTTAACAGGAGTTGCAGGTCCGGATAGCTTAGAAGGTCAGCCGGCAGGGACAGTTTTTATCGGTT
TGTCAAGTTCCAAAAGAACAATGGCAATCAAAGTGTTAATTGGCGGACGCAGTCGGTCTGATGTGCGTTATATCGCTGTT
TTACATGCTTTTAATTTAGTACGTCAAACTTTATTATCTCATAAAAATTTAGTATAA

Domains

Predicted by InterproScan.

Probable molybdopterin binding domain (MoCF_biosynth)

(5-170)

Damage-inducible protein CinA KH domain (CinA_KH)

(178-253)

Competence-damaged protein (CinA)

(259-411)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mutans UA159

99.522

100

0.995
  cinA Streptococcus mitis SK321

72.249

100

0.722
  cinA Streptococcus mitis NCTC 12261

71.77

100

0.718
  cinA Streptococcus pneumoniae TIGR4

70.574

100

0.706
  cinA Streptococcus pneumoniae Rx1

70.335

100

0.703
  cinA Streptococcus pneumoniae R6

70.335

100

0.703
  cinA Streptococcus pneumoniae D39

70.096

100

0.701
  cinA Streptococcus suis isolate S10

55.474

98.325

0.545
  cinA Bacillus subtilis subsp. subtilis str. 168

46.005

98.804

0.455

Multiple sequence alignment