Detailed information    

insolico Bioinformatically predicted

Overview

Name   brsM   Type   Regulator
Locus tag   SMUNUM_RS09990 Genome accession   NZ_AP014571
Coordinates   2016191..2016637 (+) Length   148 a.a.
NCBI ID   WP_002262388.1    Uniprot ID   -
Organism   Streptococcus mutans LP13     
Function   repress competence development; negative regulate BrsR activity (predicted from homology)   
Competence regulation

Genomic Context

Location: 2011191..2021637
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SMUNUM_RS09965 (SMNUM_1889) - 2012707..2014278 (-) 1572 WP_002280523.1 hypothetical protein -
  SMUNUM_RS09970 (SMNUM_1890) - 2014512..2014811 (-) 300 WP_002262384.1 DUF1292 domain-containing protein -
  SMUNUM_RS09975 (SMNUM_1891) ruvX 2014892..2015311 (-) 420 WP_002262385.1 Holliday junction resolvase RuvX -
  SMUNUM_RS09980 (SMNUM_1892) - 2015308..2015577 (-) 270 WP_002262386.1 IreB family regulatory phosphoprotein -
  SMUNUM_RS09985 (SMNUM_1894) brsR 2015745..2016178 (+) 434 Protein_1916 bacteriocin genes transcriptional regulator BrsR -
  SMUNUM_RS09990 (SMNUM_1895) brsM 2016191..2016637 (+) 447 WP_002262388.1 bacteriocin genes regulator BrsM Regulator
  SMUNUM_RS09995 - 2016628..2016840 (-) 213 WP_002262389.1 hypothetical protein -
  SMUNUM_RS10000 (SMNUM_1896) - 2016967..2017392 (-) 426 WP_002264551.1 hypothetical protein -
  SMUNUM_RS10005 (SMNUM_1897) spx 2017643..2018041 (-) 399 WP_002262391.1 transcriptional regulator Spx -
  SMUNUM_RS10010 (SMNUM_1898) recA 2018126..2019277 (-) 1152 WP_002262392.1 recombinase RecA Machinery gene
  SMUNUM_RS10015 (SMNUM_1899) cinA 2019317..2020573 (-) 1257 WP_002270966.1 competence/damage-inducible protein A Machinery gene
  SMUNUM_RS10020 (SMNUM_1900) - 2020722..2021282 (-) 561 WP_002268198.1 DNA-3-methyladenine glycosylase I -

Sequence

Protein


Download         Length: 148 a.a.        Molecular weight: 17106.61 Da        Isoelectric Point: 10.1992

>NTDB_id=66017 SMUNUM_RS09990 WP_002262388.1 2016191..2016637(+) (brsM) [Streptococcus mutans LP13]
MKILKQIITYSFIGIGIGSLMNYFIAIFFFPNSNPLGVPSFVQLFSSVSQATAVQLFIFALLGVLQGFASSLFKNEKLSL
LTTSLIHYLFIVLPLLLAGSYLHWFYMTRKYFVFSFLLVSIIYILIYLFCYFENKKNIQKINKKLHQI

Nucleotide


Download         Length: 447 bp        

>NTDB_id=66017 SMUNUM_RS09990 WP_002262388.1 2016191..2016637(+) (brsM) [Streptococcus mutans LP13]
ATGAAAATACTCAAACAGATTATTACTTACAGTTTTATTGGTATAGGAATCGGTTCTTTAATGAATTATTTCATAGCCAT
CTTCTTTTTCCCAAATAGTAATCCACTTGGTGTCCCAAGTTTTGTTCAACTTTTTTCATCAGTTTCACAGGCAACAGCAG
TCCAACTTTTCATTTTTGCTCTTCTAGGCGTTTTACAAGGATTTGCTAGCAGCCTCTTTAAAAATGAAAAACTCAGTCTA
CTAACCACAAGCTTGATTCACTATTTATTCATTGTCCTACCACTTCTCTTAGCCGGATCTTATTTACACTGGTTTTACAT
GACTCGGAAATATTTCGTTTTTTCTTTCCTTTTAGTTTCTATTATTTATATCCTCATTTACTTATTCTGCTATTTTGAAA
ATAAAAAAAACATTCAAAAAATCAATAAGAAGCTGCATCAAATATAA

Domains

Predicted by InterproScan.

Protein of unknown function (DUF3021) (DUF3021)

(5-145)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  brsM Streptococcus mutans UA159

100

100

1

Multiple sequence alignment