Detailed information NTG0066002

Bioinformatically predicted

Overview

• Name: cytR
• Type: Regulator
• Locus tag: H7R19_RS23365
• Genome accession: NZ_AP022098
• Coordinates: 4876821..4877846 (+)
• Length: 341 a.a.
• NCBI ID: WP_000644904.1
• Uniprot ID: P0ACN8
• Organism: Escherichia coli strain WP4-S18-ESBL-09
• Function: promote competence gene expression (predicted from homology) Competence regulation

Genomic Context

Location: 4871821..4882846

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H7R19_RS23355 (WP4S18E09_45440)	rpmE	4874052..4874264 (-)	213	WP_000710769.1	50S ribosomal protein L31	-
H7R19_RS23360 (WP4S18E09_45450)	priA	4874467..4876665 (+)	2199	WP_022646377.1	primosomal protein N'	Machinery gene
H7R19_RS23365 (WP4S18E09_45460)	cytR	4876821..4877846 (+)	1026	WP_000644904.1	DNA-binding transcriptional regulator CytR	Regulator
H7R19_RS23370 (WP4S18E09_45470)	ftsN	4877938..4878897 (+)	960	WP_000068834.1	cell division protein FtsN	-
H7R19_RS23375 (WP4S18E09_45480)	hslV	4878990..4879520 (+)	531	WP_000208242.1	ATP-dependent protease subunit HslV	-
H7R19_RS23380 (WP4S18E09_45490)	hslU	4879530..4880861 (+)	1332	WP_001293344.1	HslU--HslV peptidase ATPase subunit	-
H7R19_RS23385 (WP4S18E09_45500)	menA	4880928..4881854 (+)	927	WP_001305044.1	1,4-dihydroxy-2-naphthoate polyprenyltransferase	-
H7R19_RS23390 (WP4S18E09_45510)	rraA	4881947..4882432 (+)	486	WP_000872908.1	ribonuclease E activity regulator RraA	-
H7R19_RS23395 (WP4S18E09_45520)	zapB	4882517..4882762 (-)	246	WP_001296623.1	septal ring assembly protein ZapB	-

Sequence

Protein

• Length: 341 a.a.
• Molecular weight: 37819.78 Da
• Isoelectric Point: 6.3842

>NTDB_id=66002 H7R19_RS23365 WP_000644904.1 4876821..4877846(+) (cytR) [Escherichia coli strain WP4-S18-ESBL-09]
MKAKKQETAATMKDVALKAKVSTATVSRALMNPDKVSQATRNRVEKAAREVGYLPQPMGRNVKRNESRTILVIVPDICDP
FFSEIIRGIEVTAANHGYLVLIGDCAHQNQQEKTFIDLIITKQIDGMLLLGSRLPFDASIEEQRNLPPMVMANEFAPELE
LPTVHIDNLTAAFDAVNYLYEQGHKRIGCIAGPEEMPLCHYRLQGYVQALRRCGIMVDPQYIARGDFTFEAGSKAMQQLL
DLPQPPTAVFCHSDVMALGALSQAKRQGLKVPEDLSIIGFDNIDLTQFCDPPLTTIAQPRYEIGREAMLLLLDQMQGQHV
GSGSRLMDCELIIRGSTRALP

Nucleotide

• Length: 1026 bp

>NTDB_id=66002 H7R19_RS23365 WP_000644904.1 4876821..4877846(+) (cytR) [Escherichia coli strain WP4-S18-ESBL-09]
GTGAAAGCGAAGAAGCAGGAAACTGCCGCGACCATGAAAGACGTTGCCCTCAAGGCAAAAGTCTCTACAGCGACTGTCTC
CCGAGCATTAATGAATCCCGATAAAGTCTCCCAGGCCACCCGTAATCGGGTTGAAAAAGCGGCCCGGGAAGTGGGTTATT
TACCGCAGCCTATGGGGCGCAACGTCAAGCGTAATGAATCCCGCACCATTCTGGTGATTGTCCCGGATATCTGCGACCCT
TTCTTTAGCGAAATTATTCGCGGTATCGAAGTTACGGCGGCAAATCACGGATATCTGGTGCTGATTGGCGACTGTGCGCA
TCAAAATCAGCAGGAAAAAACCTTTATCGATTTGATCATCACCAAGCAAATTGATGGCATGTTGCTGCTGGGTTCAAGGC
TGCCGTTTGATGCCAGCATTGAGGAACAGCGTAATCTGCCGCCGATGGTGATGGCGAACGAATTTGCACCGGAACTGGAG
CTACCTACCGTTCATATAGACAATCTGACCGCCGCATTTGATGCAGTAAATTATTTATATGAGCAAGGGCATAAACGGAT
TGGCTGTATAGCCGGTCCCGAAGAGATGCCGCTGTGTCACTACCGCCTGCAAGGTTACGTTCAGGCGCTGCGTCGCTGCG
GCATTATGGTTGATCCGCAATACATCGCCCGTGGCGACTTCACCTTCGAAGCCGGAAGCAAAGCAATGCAACAGCTGCTT
GATCTTCCACAACCGCCTACTGCTGTCTTCTGCCATAGTGATGTGATGGCGCTCGGCGCACTTTCTCAGGCAAAACGCCA
GGGGCTGAAAGTCCCGGAAGACCTTTCCATAATCGGTTTTGATAACATCGACCTGACGCAATTTTGTGATCCGCCGCTGA
CAACCATCGCGCAGCCGCGTTACGAAATCGGTCGGGAAGCTATGCTGTTATTGCTTGATCAAATGCAGGGGCAACACGTT
GGCAGTGGCTCTCGTTTAATGGACTGCGAACTTATCATCCGGGGATCAACACGCGCGTTACCTTAA

Domains

Predicted by InterProScan.

• Bacterial regulatory proteins, lacI family (LacI) (11-56)

• Periplasmic binding protein-like domain (Peripla_BP_3) (176-337)

3D structure

• AlphaFold DB: P0ACN8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
cytR	Vibrio parahaemolyticus RIMD 2210633	64.179	98.24	0.63
cytR	Vibrio cholerae C6706	65.443	95.894	0.628