Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   MF133_RS10105 Genome accession   NZ_CP092181
Coordinates   2230032..2231273 (+) Length   413 a.a.
NCBI ID   WP_010675822.1    Uniprot ID   A0A2L0TT63
Organism   Aeromonas caviae strain 211703     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2225032..2236273
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MF133_RS10080 (MF133_10080) ampD 2225411..2225983 (-) 573 WP_239054130.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -
  MF133_RS10085 (MF133_10085) - 2226112..2226582 (+) 471 WP_042015101.1 retropepsin-like aspartic protease -
  MF133_RS10090 (MF133_10090) nadC 2226586..2227449 (+) 864 WP_151027296.1 carboxylating nicotinate-nucleotide diphosphorylase -
  MF133_RS10095 (MF133_10095) - 2227760..2228194 (+) 435 WP_042015100.1 prepilin-type N-terminal cleavage/methylation domain-containing protein -
  MF133_RS10100 (MF133_10100) pilB 2228198..2229904 (+) 1707 WP_041213997.1 PilB family type IVa pilus assembly ATPase TapB Machinery gene
  MF133_RS10105 (MF133_10105) pilC 2230032..2231273 (+) 1242 WP_010675822.1 type II secretion system F family protein Machinery gene
  MF133_RS10110 (MF133_10110) pilD 2231351..2232226 (+) 876 WP_239054131.1 A24 family peptidase Machinery gene
  MF133_RS10115 (MF133_10115) coaE 2232245..2232859 (+) 615 WP_239054132.1 dephospho-CoA kinase -
  MF133_RS10120 (MF133_10120) zapD 2232897..2233619 (+) 723 WP_010675825.1 cell division protein ZapD -
  MF133_RS10125 (MF133_10125) yacG 2233630..2233824 (+) 195 WP_039040499.1 DNA gyrase inhibitor YacG -
  MF133_RS10130 (MF133_10130) mutT 2233882..2234286 (-) 405 WP_191967205.1 8-oxo-dGTP diphosphatase MutT -
  MF133_RS10135 (MF133_10135) - 2234295..2235479 (-) 1185 WP_239054133.1 tetratricopeptide repeat protein -

Sequence

Protein


Download         Length: 413 a.a.        Molecular weight: 45435.37 Da        Isoelectric Point: 9.9380

>NTDB_id=656161 MF133_RS10105 WP_010675822.1 2230032..2231273(+) (pilC) [Aeromonas caviae strain 211703]
MATLAQKRNAPKKVFSYRWHGVNRKGQKVSGELQADSITTVKAELRKQGVNVTRVSKQSQGLFSKGGAKIKPMDIAVISR
QITTMLSAGVPLVQSLQIIARGHEKAAVRELIGQIAADVETGTPLSEALRRHPRHFDDLYCDLVEAGEQSGALETIYDRI
AIYREKNEALKSKIKKAMFYPSMVILVAIVVTSILLLFVIPQFEDIFKSFGAELPAFTRFVIAISRFMQEWWYAIFGGAA
LAVFLYVRAWRKSQKVRDNTDKFILTIPVVGNILHKAAMARFARTLSTTFSAGIPLVDALVSAAGASGNYVYRTATMAIR
NEVVAGMQINVAMRTVDLFPDMVTQMVMIGEESGAIDDMLSKVAAIFEQEVDDMVDGLTSLLEPIIMVVLGVLVGGMVVA
MYLPIFKLGSVIH

Nucleotide


Download         Length: 1242 bp        

>NTDB_id=656161 MF133_RS10105 WP_010675822.1 2230032..2231273(+) (pilC) [Aeromonas caviae strain 211703]
ATGGCCACATTAGCTCAAAAACGCAACGCACCGAAAAAAGTCTTCTCCTACCGCTGGCACGGCGTCAACCGCAAGGGACA
GAAGGTCTCCGGCGAGCTGCAAGCCGACAGCATCACCACCGTCAAGGCCGAGCTGCGCAAGCAGGGCGTCAACGTCACCA
GGGTCAGCAAGCAGAGCCAGGGGCTCTTCTCCAAGGGCGGCGCCAAGATCAAGCCGATGGACATCGCCGTCATCTCCCGC
CAGATCACTACCATGCTCTCCGCCGGCGTGCCTCTGGTGCAGAGTCTTCAGATCATTGCTCGCGGCCACGAGAAAGCGGC
TGTGCGCGAGCTCATCGGCCAGATCGCCGCCGATGTGGAAACAGGCACCCCGCTCTCGGAGGCGTTGCGCCGCCATCCTC
GCCACTTCGACGACCTCTATTGCGACCTAGTCGAGGCCGGGGAGCAATCCGGTGCCCTGGAGACCATCTACGACCGTATC
GCCATCTACCGCGAGAAGAACGAAGCCCTCAAATCCAAGATCAAGAAGGCCATGTTCTATCCGTCCATGGTCATTCTGGT
GGCCATCGTCGTCACCTCCATCCTGCTGCTCTTCGTCATTCCCCAGTTCGAGGATATCTTCAAGAGCTTCGGTGCCGAGC
TGCCCGCCTTTACCCGGTTCGTCATCGCCATCTCCCGCTTCATGCAGGAGTGGTGGTACGCCATCTTTGGCGGCGCGGCT
CTCGCCGTCTTCCTCTATGTGCGGGCCTGGCGAAAATCCCAGAAGGTCAGGGACAACACGGACAAGTTCATCCTCACCAT
TCCCGTGGTGGGCAACATACTGCACAAGGCTGCCATGGCCCGTTTTGCCCGCACCCTCTCCACCACCTTCTCCGCCGGTA
TCCCACTGGTGGATGCCCTGGTCTCGGCGGCCGGAGCATCGGGCAACTATGTCTATCGCACTGCGACCATGGCCATTCGC
AACGAGGTGGTGGCCGGCATGCAGATCAACGTCGCCATGCGCACCGTGGATCTTTTCCCCGACATGGTGACCCAGATGGT
GATGATCGGTGAGGAATCCGGCGCCATCGACGACATGCTCTCCAAGGTCGCCGCCATTTTCGAACAGGAAGTGGACGACA
TGGTCGACGGCCTCACCAGCCTGCTCGAACCCATCATAATGGTGGTGCTCGGGGTGCTGGTCGGCGGCATGGTCGTGGCC
ATGTACCTCCCCATTTTCAAGCTGGGCTCTGTGATACACTGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(79-201)

Type II secretion system (T2SS), protein F (T2SSF)

(282-404)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2L0TT63

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Pseudomonas stutzeri DSM 10701

56.566

95.884

0.542
  pilC Legionella pneumophila strain ERS1305867

52.099

98.063

0.511
  pilC Acinetobacter baylyi ADP1

50.971

99.758

0.508
  pilC Acinetobacter baumannii D1279779

52.369

97.094

0.508
  pilC Vibrio cholerae strain A1552

47.368

96.61

0.458
  pilC Vibrio campbellii strain DS40M4

45.113

96.61

0.436
  pilG Neisseria meningitidis 44/76-A

41.602

93.705

0.39
  pilG Neisseria gonorrhoeae MS11

41.602

93.705

0.39
  pilC Thermus thermophilus HB27

38.75

96.852

0.375