Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   ANG_RS01225 Genome accession   NZ_AP013072
Coordinates   230901..232169 (+) Length   422 a.a.
NCBI ID   WP_003038347.1    Uniprot ID   I0S7M7
Organism   Streptococcus anginosus subsp. whileyi MAS624     
Function   facilitate localization of RecA (predicted from homology)   
Homologous recombination

Genomic Context

Location: 225901..237169
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ANG_RS01205 - 228171..228509 (-) 339 WP_003038373.1 hypothetical protein -
  ANG_RS01210 (ANG_0220) ruvA 228608..229198 (+) 591 WP_003038332.1 Holliday junction branch migration protein RuvA -
  ANG_RS01215 (ANG_0221) - 229209..229781 (+) 573 WP_003038379.1 DNA-3-methyladenine glycosylase I -
  ANG_RS01220 - 229890..230303 (-) 414 Protein_220 EamA family transporter -
  ANG_RS01225 (ANG_0223) cinA 230901..232169 (+) 1269 WP_003038347.1 competence/damage-inducible protein A Machinery gene
  ANG_RS01230 (ANG_0224) recA 232213..233361 (+) 1149 WP_038677164.1 recombinase RecA Machinery gene
  ANG_RS01235 (ANG_0225) spx 233448..233846 (+) 399 WP_003026638.1 transcriptional regulator Spx -
  ANG_RS01240 (ANG_0226) - 233984..234433 (+) 450 WP_269446318.1 SP0191 family lipoprotein -
  ANG_RS01245 (ANG_0227) - 234537..235028 (+) 492 WP_025271567.1 SP0191 family lipoprotein -
  ANG_RS01250 (ANG_0228) - 235309..235575 (+) 267 WP_009569646.1 IreB family regulatory phosphoprotein -
  ANG_RS01255 (ANG_0229) ruvX 235575..235994 (+) 420 WP_003038407.1 Holliday junction resolvase RuvX -
  ANG_RS01260 (ANG_0230) - 236012..236323 (+) 312 WP_003027765.1 DUF1292 domain-containing protein -

Sequence

Protein


Download         Length: 422 a.a.        Molecular weight: 45465.12 Da        Isoelectric Point: 6.6664

>NTDB_id=65499 ANG_RS01225 WP_003038347.1 230901..232169(+) (cinA) [Streptococcus anginosus subsp. whileyi MAS624]
MKAEIIAVGTEILTGQIVNTNARFLSEKLASLGVDVYFQTAVGDNEARLLSILEIARNRSNLVILTGGLGPTEDDLTKQT
LAKFLNRRLVFDRMATEKLDRFFASRPDYARTPNNERQAQIVEGSTPLQNETGLAVGGVIGVGGVTYVVLPGPPSELKPM
VNNELVPLLATGQKLYSRVLRFFGIGESQLVTLLGDLIDAQIDPTIAPYAKTGEVTLRLSTKAGSQKEADVKFAHLEKKI
LAVQTFEKQHLADLFYAYGDDSSLGQTAFELLIRAGKTVTAAESLTAGLFQATLANFAGASNVFSGGFVTYSMEEKSRML
GIPLADLEKHGVVSAFTAEKMAEQARKLTASDYAVSLTGVAGPDSLEGHPAGTVYIGLATTEDVQSIKVNIAGRSRTDVR
KIAVLHAFNLLRKTLLKNENML

Nucleotide


Download         Length: 1269 bp        

>NTDB_id=65499 ANG_RS01225 WP_003038347.1 230901..232169(+) (cinA) [Streptococcus anginosus subsp. whileyi MAS624]
ATGAAAGCAGAAATTATTGCTGTGGGTACTGAAATTCTGACAGGTCAGATTGTCAATACAAATGCCCGATTTTTATCGGA
AAAATTAGCGAGTCTGGGTGTAGATGTGTATTTCCAAACAGCGGTTGGAGATAATGAAGCTCGTCTGTTATCCATTTTAG
AAATTGCTCGAAATCGTAGTAATTTGGTCATCTTAACTGGAGGATTAGGCCCAACAGAAGATGACTTGACTAAGCAGACT
TTGGCAAAATTCTTAAATCGTAGGTTGGTATTTGACCGAATGGCTACGGAGAAATTGGACCGCTTTTTCGCAAGTCGACC
GGATTATGCTCGAACACCAAACAATGAGCGGCAAGCTCAGATAGTGGAAGGCTCGACTCCTCTCCAAAACGAAACCGGAC
TTGCGGTGGGAGGCGTGATTGGAGTCGGCGGCGTGACTTATGTTGTTCTCCCCGGACCGCCTAGTGAATTAAAGCCTATG
GTAAATAATGAGCTAGTTCCGCTTTTAGCGACTGGTCAAAAATTGTATTCAAGAGTCTTGCGATTCTTTGGTATCGGTGA
AAGTCAATTAGTAACTCTTTTAGGAGATTTAATTGATGCTCAGATCGATCCGACCATTGCTCCTTATGCTAAGACGGGAG
AGGTGACATTGCGATTGTCCACAAAGGCTGGCAGTCAAAAGGAAGCAGATGTTAAGTTTGCTCATTTAGAAAAGAAAATT
TTGGCAGTACAGACTTTTGAGAAACAACATTTAGCAGACCTTTTCTACGCTTATGGAGATGATAGTTCTCTGGGACAAAC
AGCTTTTGAACTGCTGATAAGAGCAGGAAAGACCGTCACAGCAGCTGAAAGTTTGACTGCAGGACTCTTTCAAGCAACTT
TGGCAAACTTTGCTGGAGCCTCCAATGTTTTTAGTGGTGGCTTTGTTACCTACAGTATGGAGGAAAAGAGCCGAATGCTG
GGCATTCCCTTGGCAGACTTAGAAAAGCATGGGGTAGTTTCAGCTTTTACAGCGGAGAAAATGGCTGAGCAGGCAAGAAA
ATTGACCGCTAGTGACTATGCGGTGAGCTTGACAGGTGTGGCAGGTCCAGACAGCTTAGAAGGACATCCAGCAGGGACAG
TTTATATCGGCTTAGCAACTACAGAGGATGTTCAGTCTATTAAGGTTAATATTGCGGGTCGCAGTCGGACAGATGTACGT
AAAATAGCCGTTCTGCATGCTTTCAATCTGCTACGAAAAACTTTATTAAAAAACGAAAATATGCTATAA

Domains

Predicted by InterproScan.

Probable molybdopterin binding domain (MoCF_biosynth)

(5-170)

Competence-damaged protein (CinA)

(263-415)

Damage-inducible protein CinA KH domain (CinA_KH)

(177-240)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB I0S7M7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mitis SK321

76.077

99.052

0.754
  cinA Streptococcus pneumoniae TIGR4

75.359

99.052

0.746
  cinA Streptococcus pneumoniae Rx1

75.359

99.052

0.746
  cinA Streptococcus pneumoniae R6

75.359

99.052

0.746
  cinA Streptococcus mitis NCTC 12261

75.12

99.052

0.744
  cinA Streptococcus pneumoniae D39

75.12

99.052

0.744
  cinA Streptococcus mutans UA159

72.104

100

0.723
  cinA Streptococcus suis isolate S10

55.048

98.578

0.543
  cinA Bacillus subtilis subsp. subtilis str. 168

45.455

99.052

0.45

Multiple sequence alignment