Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   LQ065_RS12730 Genome accession   NZ_CP091240
Coordinates   2649998..2651242 (-) Length   414 a.a.
NCBI ID   WP_002359002.1    Uniprot ID   A0AAJ2D447
Organism   Enterococcus faecalis strain 249     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 2644998..2656242
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LQ065_RS12700 (LQ065_12700) - 2645316..2646779 (-) 1464 WP_002404788.1 glycoside hydrolase family 1 protein -
  LQ065_RS12705 (LQ065_12705) - 2646761..2647102 (-) 342 WP_002359005.1 PTS lactose/cellobiose transporter subunit IIA -
  LQ065_RS13605 - 2647122..2648368 (-) 1247 Protein_2486 PTS transporter subunit EIIC -
  LQ065_RS12720 (LQ065_12720) - 2648373..2648678 (-) 306 WP_002359003.1 PTS lactose transporter subunit IIB -
  LQ065_RS12725 (LQ065_12725) recA 2648838..2649884 (-) 1047 WP_002354860.1 recombinase RecA Machinery gene
  LQ065_RS12730 (LQ065_12730) cinA 2649998..2651242 (-) 1245 WP_002359002.1 competence/damage-inducible protein A Machinery gene
  LQ065_RS12735 (LQ065_12735) - 2651434..2652639 (+) 1206 WP_002359001.1 hypothetical protein -
  LQ065_RS12740 (LQ065_12740) - 2652717..2653346 (-) 630 WP_002365397.1 NAD(P)-dependent oxidoreductase -
  LQ065_RS12745 (LQ065_12745) - 2653405..2653830 (-) 426 WP_002383201.1 Rrf2 family transcriptional regulator -
  LQ065_RS12750 (LQ065_12750) - 2653919..2654302 (-) 384 WP_002358999.1 YccF domain-containing protein -
  LQ065_RS12755 (LQ065_12755) - 2654466..2655257 (+) 792 WP_002354848.1 hypothetical protein -

Sequence

Protein


Download         Length: 414 a.a.        Molecular weight: 45207.32 Da        Isoelectric Point: 4.6698

>NTDB_id=648780 LQ065_RS12730 WP_002359002.1 2649998..2651242(-) (cinA) [Enterococcus faecalis strain 249]
MKAEIIAVGTELLLGQVVNTNATFLSEELAALGIDVYYQTVVGDNGGRLETLLTEAEQRSDLIVLCGGLGPTEDDLTKQV
VAQHLHKSLVEDQEGLNRLHQFFQQSKRPMTENNLRQVLAIEGGQVLQNPTGLAVGSFVTEGTTSYLLLPGPPNELIPMF
QQAARPLLIDAFPQEEQLISRVLRFYGIGESQLVTEIQSLIAHQTNPTIAPYAKPNEVTLRLTVKTKDLVAGEELLTATE
EKVLAKVGDYFYGYGDDNSLAKVTVDLLLQNGQTVTAAESLTAGLFQSTLGEIAGASKIFKGGFVTYSQETKENFLGISH
ELLEEHGTVSEACAKEMAEKARQLAKSNYGLSFTGVAGDPIEGQPTGTVWIGLAEEGQPTVAECFHFNRDRNYIRQSAIM
RGLDLLRRRIINKK

Nucleotide


Download         Length: 1245 bp        

>NTDB_id=648780 LQ065_RS12730 WP_002359002.1 2649998..2651242(-) (cinA) [Enterococcus faecalis strain 249]
ATGAAAGCAGAAATCATTGCAGTCGGAACAGAATTATTACTGGGACAAGTAGTGAATACCAACGCCACCTTTTTATCAGA
AGAGTTAGCTGCGCTAGGCATCGATGTTTACTATCAGACCGTTGTTGGCGATAACGGCGGCCGCTTAGAAACGCTACTAA
CAGAAGCAGAACAAAGAAGTGATTTAATTGTCCTTTGTGGAGGGCTAGGACCTACAGAAGACGATTTAACCAAGCAAGTT
GTCGCACAACATCTCCATAAATCATTAGTAGAAGATCAAGAAGGATTGAACCGCTTGCACCAGTTTTTCCAACAGTCTAA
GCGGCCAATGACGGAAAATAATCTACGACAAGTGTTAGCCATTGAAGGTGGACAAGTTCTTCAAAACCCGACAGGATTAG
CGGTTGGTTCTTTCGTAACAGAAGGCACAACAAGCTATTTGCTCTTACCAGGGCCGCCCAATGAATTAATTCCGATGTTC
CAACAAGCGGCACGACCTTTATTGATTGATGCGTTTCCACAAGAAGAACAATTGATTTCAAGAGTCTTGCGTTTTTATGG
GATTGGTGAATCACAGCTGGTGACCGAGATTCAATCGTTGATTGCGCACCAAACGAATCCAACCATTGCGCCTTATGCTA
AGCCTAATGAAGTGACACTTCGTTTAACAGTTAAAACAAAAGACTTAGTAGCTGGCGAAGAATTATTAACAGCGACGGAA
GAAAAGGTTTTAGCTAAAGTGGGAGACTATTTTTATGGGTATGGGGATGACAATAGTTTAGCCAAGGTAACAGTGGATTT
GTTATTACAAAACGGACAAACCGTCACGGCTGCTGAGAGCCTCACTGCTGGCCTATTCCAAAGTACACTGGGGGAAATTG
CGGGTGCTTCGAAGATTTTTAAGGGAGGCTTCGTGACGTATTCGCAAGAAACAAAAGAGAACTTTTTAGGAATTTCTCAT
GAACTTTTAGAAGAACATGGCACGGTAAGTGAAGCGTGTGCCAAAGAAATGGCAGAGAAAGCGCGTCAGTTAGCTAAATC
TAACTATGGTTTATCATTTACTGGGGTCGCTGGTGACCCAATCGAAGGTCAACCGACAGGCACTGTTTGGATTGGGCTGG
CGGAAGAAGGCCAACCAACCGTTGCAGAATGTTTCCATTTTAACCGTGACCGAAATTATATTAGACAGAGTGCGATTATG
CGAGGGTTAGATCTTTTGCGGCGCCGAATCATTAATAAAAAATAA

Domains

Predicted by InterproScan.

Probable molybdopterin binding domain (MoCF_biosynth)

(5-168)

Competence-damaged protein (CinA)

(258-409)

Damage-inducible protein CinA KH domain (CinA_KH)

(180-253)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mutans UA159

52.153

100

0.527
  cinA Streptococcus mitis SK321

51.3

100

0.524
  cinA Streptococcus mitis NCTC 12261

51.064

100

0.522
  cinA Streptococcus pneumoniae TIGR4

50.355

100

0.514
  cinA Streptococcus pneumoniae D39

50.118

100

0.512
  cinA Streptococcus pneumoniae R6

49.882

100

0.51
  cinA Streptococcus pneumoniae Rx1

49.882

100

0.51
  cinA Bacillus subtilis subsp. subtilis str. 168

48.522

98.068

0.476
  cinA Streptococcus suis isolate S10

44.039

99.275

0.437