Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/blpR   Type   Regulator
Locus tag   LOD78_RS00905 Genome accession   NZ_CP090522
Coordinates   170696..171433 (+) Length   245 a.a.
NCBI ID   WP_171989915.1    Uniprot ID   -
Organism   Streptococcus parasuis strain SS17     
Function   activate transcription of early competence genes; regulation of comX expression (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Genomic island 159653..170552 170696..171433 flank 144
IScluster/Tn 168450..169801 170696..171433 flank 895


Gene organization within MGE regions


Location: 159653..171433
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LOD78_RS00840 (LOD78_00830) rnmV 159653..160219 (+) 567 WP_171989046.1 ribonuclease M5 -
  LOD78_RS00845 - 160212..160340 (+) 129 WP_274505528.1 hypothetical protein -
  LOD78_RS00850 (LOD78_00835) - 160436..160606 (+) 171 WP_239604456.1 hypothetical protein -
  LOD78_RS00855 (LOD78_00840) - 160613..160865 (+) 253 Protein_147 NUDIX domain-containing protein -
  LOD78_RS00860 (LOD78_00845) rsmA 160904..161776 (+) 873 WP_274505529.1 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))- dimethyltransferase RsmA -
  LOD78_RS00865 (LOD78_00850) - 163021..163761 (+) 741 WP_174846588.1 amino acid transporter -
  LOD78_RS00870 (LOD78_00855) - 163771..164349 (+) 579 WP_239604458.1 CPBP family intramembrane glutamic endopeptidase -
  LOD78_RS00875 (LOD78_00860) - 164361..164789 (+) 429 WP_171988959.1 Msa family membrane protein -
  LOD78_RS00880 (LOD78_00865) - 164782..165654 (+) 873 WP_274505531.1 ABC transporter ATP-binding protein -
  LOD78_RS00885 (LOD78_00870) - 165661..166431 (+) 771 WP_174846587.1 hypothetical protein -
  LOD78_RS00890 (LOD78_00875) - 166434..168149 (+) 1716 WP_174846586.1 ABC transporter ATP-binding protein -
  LOD78_RS00895 (LOD78_00880) - 168412..169801 (-) 1390 Protein_155 transposase -
  LOD78_RS00900 (LOD78_00885) - 170169..170552 (-) 384 WP_174846550.1 hypothetical protein -
  LOD78_RS00905 (LOD78_00890) comE/blpR 170696..171433 (+) 738 WP_171989915.1 response regulator transcription factor Regulator

Sequence

Protein


Download         Length: 245 a.a.        Molecular weight: 28407.32 Da        Isoelectric Point: 5.7912

>NTDB_id=643163 LOD78_RS00905 WP_171989915.1 170696..171433(+) (comE/blpR) [Streptococcus parasuis strain SS17]
MLNIFILEDDYLQQTRLENVIKQSVATNNLKYRHLEIYGKPHQLLETISEKGNHQLFFLDIEIRGEEQKGMEIAREIRLK
DPNAVIVFVSTHSEFMPVTYKYRVSALDFIDKGLPEEEFQDAVTSVLVHAYENVGRTVGEDAFVFKSEHSHVQVPFSDIL
FFETSTTVHKVILYTKTGQLEFYGKVSEIAKSDERLYQSHRAYVVNPQNIVRIDRANHMVYFEGDESCFVSKLKLKGLIE
KVENP

Nucleotide


Download         Length: 738 bp        

>NTDB_id=643163 LOD78_RS00905 WP_171989915.1 170696..171433(+) (comE/blpR) [Streptococcus parasuis strain SS17]
ATGTTAAATATTTTTATATTAGAGGATGACTATCTGCAACAAACTCGTTTAGAAAATGTCATTAAGCAGAGTGTAGCCAC
AAATAATTTGAAATACAGGCATCTAGAGATCTATGGGAAGCCCCACCAATTACTAGAGACTATTTCCGAAAAAGGAAACC
ATCAGCTATTTTTCCTGGATATAGAGATTAGGGGAGAAGAGCAAAAAGGAATGGAGATTGCGCGTGAAATCCGTTTAAAA
GACCCCAATGCGGTCATTGTTTTTGTGTCCACTCATTCGGAATTCATGCCAGTAACCTATAAATATCGCGTGTCAGCGCT
GGACTTCATTGATAAAGGATTGCCTGAGGAGGAGTTTCAGGATGCTGTTACTTCGGTTTTGGTTCATGCCTATGAAAATG
TGGGGCGCACAGTCGGAGAAGATGCTTTTGTCTTTAAAAGCGAGCATTCACATGTTCAGGTTCCTTTTTCAGATATCCTC
TTCTTTGAGACATCTACAACTGTCCATAAGGTCATTCTTTATACCAAGACAGGACAACTGGAATTCTATGGCAAGGTATC
AGAAATTGCCAAATCTGATGAACGGCTCTATCAAAGCCATCGTGCTTATGTCGTGAATCCCCAAAATATTGTACGCATTG
ATCGTGCCAACCACATGGTTTATTTTGAAGGTGATGAATCTTGTTTTGTCTCCAAGTTGAAATTAAAGGGCCTGATTGAA
AAAGTGGAGAATCCGTAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-123)

LytTr DNA-binding domain (LytTR)

(152-241)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/blpR Streptococcus mutans UA159

53.556

97.551

0.522
  comE/comE1 Streptococcus equinus JB1

45.041

98.776

0.445
  comE/comE2 Streptococcus equinus JB1

40.984

99.592

0.408
  comE/comE2 Streptococcus gordonii strain NCTC7865

36.885

99.592

0.367
  comE/comE1 Streptococcus gordonii str. Challis substr. CH1

36.885

99.592

0.367
  comE Streptococcus mitis SK321

35.458

100

0.363
  comE Streptococcus pneumoniae Rx1

35.458

100

0.363
  comE Streptococcus pneumoniae D39

35.458

100

0.363
  comE Streptococcus pneumoniae R6

35.458

100

0.363
  comE Streptococcus pneumoniae TIGR4

35.458

100

0.363
  comE Streptococcus mitis NCTC 12261

35.458

100

0.363