Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   LOD78_RS00425 Genome accession   NZ_CP090522
Coordinates   76380..77561 (+) Length   393 a.a.
NCBI ID   WP_274505496.1    Uniprot ID   -
Organism   Streptococcus parasuis strain SS17     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 71380..82561
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LOD78_RS00410 (LOD78_00405) mutL 71911..73848 (+) 1938 WP_171989052.1 DNA mismatch repair endonuclease MutL -
  LOD78_RS00415 (LOD78_00410) ruvA 74094..74684 (+) 591 WP_171989013.1 Holliday junction branch migration protein RuvA -
  LOD78_RS00420 (LOD78_00415) - 75774..76343 (+) 570 WP_274505495.1 DNA-3-methyladenine glycosylase I -
  LOD78_RS00425 (LOD78_00420) cinA 76380..77561 (+) 1182 WP_274505496.1 competence/damage-inducible protein A Machinery gene
  LOD78_RS00430 (LOD78_00425) recA 77613..78767 (+) 1155 WP_171989010.1 recombinase RecA Machinery gene
  LOD78_RS00435 (LOD78_00430) spx 78981..79379 (+) 399 WP_024392835.1 transcriptional regulator Spx -
  LOD78_RS00440 (LOD78_00435) - 79489..79755 (+) 267 WP_274505497.1 IreB family regulatory phosphoprotein -
  LOD78_RS00445 (LOD78_00440) ruvX 79755..80174 (+) 420 WP_130554426.1 Holliday junction resolvase RuvX -
  LOD78_RS00450 (LOD78_00445) - 80186..80506 (+) 321 WP_024392832.1 DUF1292 domain-containing protein -
  LOD78_RS00455 (LOD78_00450) - 80782..81330 (+) 549 WP_174846502.1 nucleotidyltransferase family protein -
  LOD78_RS00460 (LOD78_00455) comX/sigX 81512..81982 (+) 471 WP_024392830.1 sigma-70 family RNA polymerase sigma factor Regulator

Sequence

Protein


Download         Length: 393 a.a.        Molecular weight: 42699.58 Da        Isoelectric Point: 4.3882

>NTDB_id=643159 LOD78_RS00425 WP_274505496.1 76380..77561(+) (cinA) [Streptococcus parasuis strain SS17]
MKAELIAVGTEILTGQIVNTNAQFLSEKCAELGIDVYFHTAVGDNEQRLLSVLEIASKRSDLVILCGGLGPTEDDLTKQT
LATFLQKELVADELAMAKLDRFFASRPGRVRTPNNERQAQIVEGSQALQNPAGLAVGGMIEQDGVTYIVLPGPPSELKAM
FSESLLPFLTQSQQQLYSRVLRFFGIGESQLVTVLADLIDKQTDPTLAPYAKVGEVTLRLSTKADSQEEANVRLNQLEEE
ILQRDHLRVFFYAYGDDNSLVKTVATLLEEEKQSLGILENGTGGLLQAELSLALAGQPYYSGGKIIGQLGTESGGLSEEA
SRIREELQADLGLVVSVAVKPESTVDNVLAKVYLALASTSGISKKEVDLGGYSWQYLRQLACLQALDFVRNTL

Nucleotide


Download         Length: 1182 bp        

>NTDB_id=643159 LOD78_RS00425 WP_274505496.1 76380..77561(+) (cinA) [Streptococcus parasuis strain SS17]
ATGAAAGCAGAATTAATTGCTGTTGGAACAGAAATATTGACAGGTCAAATTGTGAATACGAATGCTCAATTCTTGTCAGA
AAAATGTGCAGAGCTAGGTATCGATGTATACTTCCACACTGCTGTAGGTGATAATGAACAGCGACTATTGTCTGTACTTG
AAATTGCAAGTAAACGAAGTGATCTGGTCATTTTATGTGGTGGTTTAGGTCCTACTGAAGACGACTTGACTAAGCAAACT
TTAGCGACATTTTTGCAAAAAGAGTTGGTTGCTGACGAACTAGCGATGGCAAAATTAGACCGTTTTTTTGCCAGTCGACC
AGGTCGTGTTCGCACACCTAATAATGAGCGTCAAGCACAGATTGTGGAGGGAAGTCAGGCGCTACAGAACCCAGCTGGTT
TAGCTGTAGGTGGTATGATTGAGCAAGATGGTGTGACCTATATTGTTTTGCCTGGCCCACCAAGTGAACTCAAGGCCATG
TTTTCTGAGAGTCTGTTACCTTTTTTGACTCAATCTCAGCAACAACTTTACTCGCGTGTCCTACGCTTTTTTGGAATAGG
TGAAAGCCAGTTGGTGACTGTTTTAGCGGATTTGATTGACAAGCAGACAGACCCGACTCTTGCGCCTTATGCAAAAGTTG
GAGAGGTGACGCTTCGTTTGTCTACGAAGGCAGATAGCCAGGAAGAAGCGAACGTGCGTTTGAATCAGTTGGAAGAAGAG
ATATTGCAACGTGACCATTTGAGAGTTTTTTTCTATGCATATGGGGATGATAATAGTTTGGTTAAAACCGTAGCGACTCT
TTTAGAGGAAGAGAAACAATCTTTGGGCATCCTAGAGAATGGAACAGGTGGTTTATTACAAGCAGAATTGAGTCTGGCTT
TGGCTGGTCAGCCGTATTATAGTGGAGGAAAAATCATCGGTCAGCTAGGGACAGAATCGGGCGGGCTATCAGAAGAAGCA
AGTCGCATTCGGGAGGAACTACAAGCTGATTTAGGGCTAGTTGTGTCGGTGGCAGTCAAACCAGAATCAACAGTAGACAA
CGTACTTGCTAAAGTATATCTAGCCTTGGCCAGTACCTCGGGTATTTCCAAAAAAGAGGTAGATTTAGGAGGTTATTCAT
GGCAATACCTTCGTCAACTTGCTTGTTTACAGGCGTTAGATTTTGTACGAAACACTTTGTGA

Domains

Predicted by InterproScan.

Damage-inducible protein CinA KH domain (CinA_KH)

(178-244)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-170)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus suis isolate S10

87.023

100

0.87
  cinA Streptococcus mitis SK321

55.529

100

0.588
  cinA Streptococcus mitis NCTC 12261

55.288

100

0.585
  cinA Streptococcus pneumoniae TIGR4

55.048

100

0.583
  cinA Streptococcus pneumoniae Rx1

55.048

100

0.583
  cinA Streptococcus pneumoniae R6

55.048

100

0.583
  cinA Streptococcus pneumoniae D39

54.808

100

0.58
  cinA Streptococcus mutans UA159

54.988

100

0.575
  cinA Bacillus subtilis subsp. subtilis str. 168

47.213

77.608

0.366